Month: March 2021

In an article, author is SLAVIK, J, once mentioned the application of 619-58-9, Name is 4-Iodobenzoic acid, molecular formula is C7H5IO2, molecular weight is 248.02, MDL number is MFCD00002533, category is iodides-buliding-blocks. Now introduce a scientific discovery about this category, SDS of cas: 619-58-9.

QUATERNARY ALKALOIDS FROM THALICTRUM-MINUS SUBSP ELATUM (JACQ) STOY ET STEFANOV

Quaternary alkaloids berberine (chloride, 0.18%), and, after transformation into the iodides, magnoflorine (iodide, 1.06%), jatrorrhizine (iodide, 0.066%), thalphenine (iodide, 0.040%) and thalifendine (iodide, 0.021%) were isolated, after separation of the tertiary bases (0.38%), from the root of Thalicrum minus subsp. elatum (JACQ.) STOJ. et STEFANOV of Czechoslovak origin (1.8% alkaloid content). The aerial parts (0.013% alkaloids) in their quaternary fraction contain only negligible amounts of magnoflorine, berberine, and coptisine (which is the first time coptisine was found in the Thalictrum genus).

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The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Name: 4-Iodobenzonitrile, 3058-39-7, Name is 4-Iodobenzonitrile, SMILES is N#CC1=CC=C(I)C=C1, in an article , author is Ishii, Jun, once mentioned of 3058-39-7.

Congenital goitrous hypothyroidism is caused by dysfunction of the iodide transporter SLC26A7

Iodide transport and storage in the thyroid follicles is crucial for thyroid hormone synthesis. Pendrin, the iodide exporter that transports iodide to thyroid follicles, is responsible for Pendred syndrome, a disorder characterized by congenital hypothyroidism and hearing loss. However, thyroid hormone levels are basically normal in patients with Pendred syndrome, indicating the presence of another unknown iodide transporter. Here, we show that SLC26A7 is a novel iodide transporter in the thyroid. We observe that SLC26A7 is specifically expressed in normal thyroid tissues and demonstrate its function in iodide transport. Using whole-exome sequencing, we also find a homozygous nonsense mutation in SLC26A7 (c.1498 C > T; p.Gln500Ter) in two siblings with congenital goitrous hypothyroidism. The mutated SLC26A7 protein shows an abnormal cytoplasmic localisation and lacks the iodide transport function. These results reveal that SLC26A7 functions as a novel iodide transporter in the thyroid and its dysfunction affects thyroid hormonogenesis in humans and causes congenital goitrous hypothyroidism.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 3058-39-7, you can contact me at any time and look forward to more communication. Name: 4-Iodobenzonitrile.

Related Products of 88-67-5, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 88-67-5, Name is 2-Iodobenzoic acid, SMILES is O=C(O)C1=CC=CC=C1I, belongs to iodides-buliding-blocks compound. In a article, author is Wlassics, Ivan, introduce new discover of the category.

COUPLING REACTIONS OF CHLOROFLUORO AND PERFLUOROALKYL IODIDES

Coupling reactions of chlorofluoro- and perfluoroalkyl iodides R(f)-I with R(f) = ClCF(2)CFCl-(CF(2))(3)CF(2)-, ClCF(2)CFClO(CF(2))(3)CF(2)-, ClCF(2)CFCl-, (CF(3))(2)CF-, (CF(3))(2)CFCF(2)CF(2)- in the presence of a zinc/solvent system give dimers in good yields. Both homodimerizations (one iodide) and heterodimerizations (two different iodides) have been studied. The effect of temperature and solvent is shown. The zinc mediated dechlorination of vicinal chlorine atoms in the dimers afforded terminal alkenes and dienes.

Related Products of 88-67-5, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 88-67-5 is helpful to your research.

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Category: iodides-buliding-blocks, 88-67-5, Name is 2-Iodobenzoic acid, molecular formula is C7H5IO2, belongs to iodides-buliding-blocks compound. In a document, author is Ozawa, Hironobu, introduce the new discover.

Effects of the Alkyl Chain Length of Imidazolium Iodide in the Electrolyte Solution on the Performance of Black-Dye-Based Dye-Sensitized Solar Cells

Five kinds of electrolyte solutions containing the imidazolium iodide with a different alkyl chain length (DMImI, EMImI, MPImI, DMPImI and HMImI; DMImI = 1,3-dimethylimidazolium iodide, EMImI = 1-ethyl-3- methylimidazolium iodide, MPImI = 1-methyl-3-n-propylimidazolium iodide, DMPImI = 1,2-dimethyl-3- n-propylimidazolium iodide, HMImI = 1-n-hexyl-3-methylimidazolium iodide) have been prepared to investigate the effects of the alkyl chain length of the imidazolium iodide on the performance of dyesensitized solar cells (DSCs) with Black dye and D131. The photocurrent density (Jsc) increased and the fill factor (FF) decreased with increasing the alkyl chain length of the imidazolium iodide. Electrochemical impedance spectroscopic measurements of the DSCs revealed that the conduction band energy of TiO2 shifted to the positive direction and the diffusion resistance of the redox couple in the electrolyte solution increased with increasing the alkyl chain length of the imidazolium iodide. Therefore, the observed increment of the Jsc value seems to be attributed mainly to the conduction band energy shift of TiO2, and the observed decrement of the FF value would be caused by increasing the diffusion resistance of the redox couple in the electrolyte solution. The conversion efficiency of the DSCs was found to depend on the ion conductivity of the electrolyte solution, which is closely related to the alkyl chain length of the imidazolium iodide. This study demonstrated that the conversion efficiency could be improved by using EMImI instead of the conventional imidazolium iodide (DMPImI) due to the larger ion conductivity with a slightly higher conduction band energy of TiO2. (C) 2014 Elsevier Ltd. All rights reserved.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 88-67-5. Category: iodides-buliding-blocks.

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 2043-57-4, Name is 1,1,1,2,2,3,3,4,4,5,5,6,6-Tridecafluoro-8-iodooctane, SMILES is ICCC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F, in an article , author is Amachi, S, once mentioned of 2043-57-4, SDS of cas: 2043-57-4.

Active transport and accumulation of iodide by newly isolated marine bacteria

Iodide (I-)-accumulating bacteria were isolated from marine sediment by an autoradiographic method with radioactive (125)1-. When they were grown in a liquid medium containing 0.1 muM iodide, 79 to 89% of the iodide was removed from the medium, and a corresponding amount of iodide was detected in the cells. Phylogenetic analysis based on 16S rRNA gene sequences indicated that iodide-accumulating bacteria were closely related to Flexibacter aggregans NBRC15975 and Arenibacter troitsensis, members of the family Flavobacteriaceae. When one of the strains, strain C-21, was cultured with 0.1 muM iodide, the maximum iodide content and the maximum concentration factor for iodide were 220 +/-3.6 (mean +/- standard deviation) pmol of iodide per mg of dry cells and 5.5 x 10(3), respectively. In the presence of much higher concentrations of iodide (1 muM to 1 mM), increased iodide content but decreased concentration factor for iodide were observed. An iodide transport assay was carried out to monitor the uptake and accumulation of iodide in washed cell suspensions of iodide-accumulating bacteria. The uptake of iodide was observed only in the presence of glucose and showed substrate saturation kinetics, with an apparent affinity constant for transport and a maximum velocity of 0.073 p,M and 0.55 ptnol min(-1) mg of dry cells(-1), respectively. The other dominant species of iodine in terrestrial and marine environments, iodate (10(3)(-)), was not transported.

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Chemistry is an experimental science, SDS of cas: 460-37-7, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 460-37-7, Name is 1,1,1-Trifluoro-3-iodopropane, molecular formula is C3H4F3I, belongs to iodides-buliding-blocks compound. In a document, author is HASSAN, SSM.

SEQUENTIAL FLOW-INJECTION POTENTIOMETRIC DETERMINATION OF IODIDE AND IODINE IN POVIDONE-IODINE PHARMACEUTICALS

A potentiometric sensor-based flow-injection system for determining iodide is described. The system utilizes a flow-through sandwich cell and incorporates iron (II)-tris bathophenanthroline iodide ion pair complex as an exchange site in a PVC matrix membrane. The sensor displays a fast response for 10(-1) to 10(-6) M iodide ion with an anionic slope of 59.1 +/- 0.3 mV/concentration decade over the pH range 1 to 11. The experimental setup offers a precise, sensitive, selective and high sample throughput technique for determining iodide and iodine over a wide range of concentration. The limit of detection is 0.5 ppm iodide in a 20 muL sample. The average recovery is 99.8%, and the mean standard deviation is 0.5%. Sequential flow-injection determination of iodide and iodine in some pharmaceutical preparations containing povidone iodine is performed by sample injection in a sodium sulfate-ascorbic acid stream and monitoring of the total iodide equivalent to I- and I2. This is followed by injection of a second sample in an alkaline resorcinol stream and measuring of the iodide equivalent to I- and 1/2 I2. Iodine and iodide concentrations are calculated from the consecutive signals. The method gives results in good agreement with those obtained by the United States Pharmacopeia.

Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law. In my other articles, you can also check out more blogs about 460-37-7. SDS of cas: 460-37-7.

Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Category: iodides-buliding-blocks, 76801-93-9, Name is 5-Amino-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide, molecular formula is C14H18I3N3O6, belongs to iodides-buliding-blocks compound. In a document, author is KOH, T, introduce the new discover.

DETERMINATION OF MICRO-AMOUNTS OF IODIDE IN GEOTHERMAL WATER USING AN ION-SELECTIVE ELECTRODE

Iodide in various geothermal water samples was determined simply and rapidly with an iodide ion selective electrode. Two procedures were investigated for the determination of iodide. The first method is a direct method in which the iodide content in the geothermal water samples was directly measured with the iodide electrode after the addition of sodium hydrogen sulfite, a definite amount of iodide and ionic strength adjustment buffer. The other is a solvent extraction method in which iodide in the samples oxidized in advance by hydrogen peroxide was extracted into carbon tetrachloride. The iodide back-extracted into an aqueous sulfite solution was measured with the iodide electrode. Both procedures were successfully applied to the determination of iodide in the concentration below 1 ppm in various geothermal water samples with a relative standard deviation of 1.8%, and the results obtained by the proposed method were in good agreement with those by the spectrophotometric method using Methylene Blue.

A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 76801-93-9. Category: iodides-buliding-blocks.

Related Products of 460-37-7, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 460-37-7, Name is 1,1,1-Trifluoro-3-iodopropane, SMILES is ICCC(F)(F)F, belongs to iodides-buliding-blocks compound. In a article, author is Bizhanova, Aigerim, introduce new discover of the category.

Minireview: The Sodium-Iodide Symporter NIS and Pendrin in Iodide Homeostasis of the Thyroid

Thyroid hormones are essential for normal development and metabolism. Thyroid hormone biosynthesis requires iodide uptake into the thyrocytes and efflux into the follicular lumen, where it is organified on selected tyrosyls of thyroglobulin. Uptake of iodide into the thyrocytes is mediated by an intrinsic membrane glycoprotein, the sodium-iodide symporter (NIS), which actively cotransports two sodium cations per each iodide anion. NIS-mediated transport of iodide is driven by the electrochemical sodium gradient generated by the Na+/K+-ATPase. NIS is expressed in the thyroid, the salivary glands, gastric mucosa, and the lactating mammary gland. TSH and iodide regulate iodide accumulation by modulating NIS activity via transcriptional and posttranscriptional mechanisms. Biallelic mutations in the NIS gene lead to a congenital iodide transport defect, an autosomal recessive condition characterized by hypothyroidism, goiter, low thyroid iodide uptake, and a low saliva/plasma iodide ratio. Pendrin is an anion transporter that is predominantly expressed in the inner ear, the thyroid, and the kidney. Biallelic mutations in the SLC26A4 gene lead to Pendred syndrome, an autosomal recessive disorder characterized by sensorineural deafness, goiter, and impaired iodide organification. In thyroid follicular cells, pendrin is expressed at the apical membrane. Functional in vitro data and the impaired iodide organification observed in patients with Pendred syndrome support a role of pendrin as an apical iodide transporter. (Endocrinology 150: 1084-1090, 2009)

Related Products of 460-37-7, One of the oldest and most widely used commercial enzyme inhibitors is aspirin, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 460-37-7.

Application of 619-58-9, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 619-58-9, Name is 4-Iodobenzoic acid, SMILES is O=C(O)C1=CC=C(I)C=C1, belongs to iodides-buliding-blocks compound. In a article, author is IWATA, K, introduce new discover of the category.

SPONTANEOUS RAMAN-SPECTRA OF THE CYANINE DYE DODCI AND ITS 6 ANALOGS USING TITANIUM-SAPPHIRE LASER EXCITATION

The infrared and spontaneous Raman spectra of the cyanine dye 3,3-diethyloxadicarbocyanine iodide (DODCI) and its six analogues, 3,3′-diethylthiacarbocyanine iodide (DTCI), 3,3′-diethyl-9-methylthiacarbocyanine iodide (MDTCI), 3,3′-diethylthiadicarbocyanine iodide (DTDCI), 3,3′-diethylselenacarbocyanine iodide (DSCI), 3,3′-diethyloxacarbocyanine iodide (DOCI), and 3,3′-diethyloxatricarbocyanine iodide (DOTCI), have been measured. A Raman spectrometer consisting of a Ti:sapphire laser and a CCD detector was found to be advantageous in avoiding the strong fluorescence of these cyanine dyes. The spectra have been compared, and several of the vibrational bands have been assigned. The locations of the CC and CN stretching vibrations suggest considerably weakened bond alternations for these molecules in solution.

Application of 619-58-9, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 619-58-9 is helpful to your research.

619-58-9, Name is 4-Iodobenzoic acid, molecular formula is C7H5IO2, belongs to iodides-buliding-blocks compound, is a common compound. In a patnet, author is Schroder-van der Elst, JP, once mentioned the new application about 619-58-9, Product Details of 619-58-9.

Dietary flavonoids and iodine metabolism

Flavonoids have inhibiting effects on the proliferation of cancer cells, including thyroidal ones. In the treatment of thyroid cancer the uptake of iodide is essential. Flavonoids are known to interfere with iodide organification ill vitro, and to cause goiter. The influence of flavonoids on iodine metabolism was studied in a human thyroid cancer cell line (FTC-133) transfected with the human sodium/iodide transporter (NIS). All flavonoids inhibited growth, and iodide uptake was decreased in most cells. NIS mRNA expression was affected during the early hours after treatment, indicating that these flavonoids can act on NIS. Pendrin mRNA expression did not change after treatment. Only myricetin increased iodide uptake. Apeginin, luteolin, kaempferol and F21388 increased the efflux of iodide, leading to a decreased retention of iodide. Instead myricetin increased the retention of iodide; this could be of use in the radioiodide treatment of thyroid cancer.

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