Month: March 2021

The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. 450412-29-0, Name is 1-Bromo-3-fluoro-2-iodobenzene, SMILES is FC1=CC=CC(Br)=C1I, in an article , author is Versloot, PM, once mentioned of 450412-29-0, Computed Properties of C6H3BrFI.

Effects of marginal iodine deficiency during pregnancy: iodide uptake by the maternal and fetal thyroid

Iodide uptake by the thyroid is an active process. Iodine deficiency and pregnancy are known to influence thyroid hormone metabolism. The aim of this study was to clarify the effects of iodine deficiency and pregnancy on iodide uptake by the thyroid. Radioiodide was injected intravenously into nonpregnant and 19-day pregnant rats receiving a normal or marginally iodine-deficient diet. The uptake of radioiodide by the thyroid was measured continuously for 4 h. The absolute iodide uptake by the maternal and fetal thyroid glands at 24 h was calculated by means of the urinary specific activity. Pregnancy resulted in a decrease in the absolute thyroidal iodide uptake. Marginal iodine deficiency had no effect on the absolute iodide uptake by the maternal thyroid. The decreased plasma inorganic iodide was compensated by an increase in thyroidal clearance. A similar compensation was not found for the fetus; the uptake of iodide by the fetal thyroid decreased by 50% during marginal iodine deficiency. This can lead to diminished thyroid hormone production, which will have a negative effect on fetal development, especially of the brain.

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450412-29-0, Name is 1-Bromo-3-fluoro-2-iodobenzene, molecular formula is C6H3BrFI, belongs to iodides-buliding-blocks compound, is a common compound. In a patnet, author is Steiss, JO, once mentioned the new application about 450412-29-0, Application In Synthesis of 1-Bromo-3-fluoro-2-iodobenzene.

Thyroid ultrasound and urinary iodide excretion in children and adolescents with diabetes mellitus (IDDM)

Background Date, studies on thyroid volume and urinary iodide excretion in patients with diabetes mellitus are not available. Sonographically determined parameters of the thyroid size are correlated to other anthropometrous data and the urinary iodide excretion is correlated to glucosuria, the HbA1c value and the diabetes duration. Method In this prospective study we evaluated sonographically the thyroid volume in 107 patients with type I diabetes mellitus and 112 healthy children. The urinary iodide excretion was measured photometrically by using a modified eerie ion arsenious acid method for spontaneous urinary specimen and if available for the 24 h collected urin. Results The thyroid volume depended on site and age. A positive correlation of the thyroid volume and age, body weight and height, could be demonstrated. Referring to reference data a goitre prevalence of 30% in juvenile patients with diabetes mellitus type I was detected. Interestingly, juvenile type I diabetics presented with an average urinary iodide excretion of 183,0 mu g iodide/g creatinine. Even the urinary iodide excretion of 162,5 mu g iodide confirmed this increased level. The urinary iodide excretion in 24 hours correlated with glucosuria and the HbA1c level. The healthy children presented with an average urinary iodide excretion of 42,6 mu g iodide/g creatinine. The mean value was clearly below the WHO recommendation of 150-300 mu g iodide/g creatinine. Only 2,8% of the healthy children examined exceeded the lower limit of this range. Conclusion In addition to the existing distinct under supply of iodide we assume an increased urinary iodide excretion in context with the osmotic diuresis in juvenile diabetics. Contrary to current opinion, that these data are correlated to the daily intake of iodide, which was calculated from urinary excretion rate, this thesis could not be affirmed for juvenile diabetics. Therefore it seems reasonable to frequently control thyroid volume and thyroid function in children and adolescents with diabetes mellitus.

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Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 610-97-9, Name is Methyl 2-iodobenzoate, SMILES is O=C(OC)C1=CC=CC=C1I, belongs to iodides-buliding-blocks compound. In a document, author is Campbell, L. W., introduce the new discover, COA of Formula: C8H7IO2.

Excited state electronic properties of sodium iodide and cesium iodide

We compute from first principles the dielectric function, loss function, lifetime and scattering rate of quasiparticles due to electronic losses, and secondary particle spectrum due to plasmon decay in two scintillating alkali halides, sodium iodide and cesium iodide. Particular emphasis is placed on quasiparticles within several multiples of the bandgap from the band edges. A theory for the decay spectra of plasmons and other electronic excitations in crystals is presented. Applications to Monte Carlo radiation transport codes are discussed. (C) 2013 Published by Elsevier B.V.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 610-97-9 is helpful to your research. COA of Formula: C8H7IO2.

Reactions catalyzed within inorganic and organic materials and at electrochemical interfaces commonly occur at high coverage and in condensed media, causing turnover rates to depend strongly on interfacial structure and composition, 19094-56-5, Name is 2-Chloro-5-iodobenzoic acid, SMILES is O=C(O)C1=CC(I)=CC=C1Cl, in an article , author is OBARSKI, N, once mentioned of 19094-56-5, Product Details of 19094-56-5.

DETERMINATION OF TRACE AMOUNTS OF LEAD AS IODIDE COMPLEX BY 3RD-ORDER DERIVATIVE SPECTROPHOTOMETRY

Third-order derivative spectrophotometry was used for the direct determination of trace amounts of lead as its iodide complex. Optimum conditions for the formation of the lead iodide complex as well as conditions for spectrum registration and obtaining its successive derivatives were chosen. The derivatives were calculated numerically using Savitzky-Golay method. The proposed direct method has been applied for determining lead (ca. 10(-4)%) in potassium iodide, zinc sulphate and cadmium sulphate with good precision and accuracy.

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Electric Literature of 19094-56-5, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 19094-56-5, Name is 2-Chloro-5-iodobenzoic acid, SMILES is O=C(O)C1=CC(I)=CC=C1Cl, belongs to iodides-buliding-blocks compound. In a article, author is STEWART, SK, introduce new discover of the category.

STEREOSELECTIVE SYNTHESIS OF VINYL IODIDES FROM VINYLBORONATE PINACOL ESTERS USING ICL

Polyenyl-1-boronic acids, with hindered pinacol esters, are difficult to transform into the corresponding Z or E-iodides under literature reaction conditions. However, reaction of trans-polyenyl-1-boronate pinacol esters with sodium methoxide, followed by monochloroiodide provides the corresponding E-iodides, while reaction with monochloroiodide, followed by sodium methoxide provides the corresponding Z-iodides.

Electric Literature of 19094-56-5, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 19094-56-5.

Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 76801-93-9, Name is 5-Amino-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide. In a document, author is Bhor, Malhari D., introducing its new discovery. Formula: C14H18I3N3O6.

Synthesis of alkyl iodides/nitriles from carbonyl compounds using novel ruthenium tris(2,2,6,6-tetramethyl-3,5-heptanedionate) as catalyst

Aldehydes and ketones were hydrogenated to the corresponding alcohols, which were then transformed in situ into their respective iodides and nitriles in good yields. A structurally well-defined O-containing transition metal complex, Ru (TMHD)(3), Was found to be the active catalyst for hydrogenation, inclination and cyanation reactions. It has high affinity for the transformation of benzylic alcohols to iodides and nitriles. (C) 2008 Elsevier Ltd. All rights reserved.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 76801-93-9 help many people in the next few years. Formula: C14H18I3N3O6.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 460-37-7, Name is 1,1,1-Trifluoro-3-iodopropane, molecular formula is C3H4F3I. In an article, author is Voronkov, MG,once mentioned of 460-37-7, Recommanded Product: 460-37-7.

Acyl iodides in organic synthesis: IV. Reaction of acetyl iodide with carboxylic acids

In contrast to acyl chlorides, reactions of acetyl iodide with monocarboxylic acids follow the exchange pattern to give the corresponding acyl iodides and acetic acid. The reaction attracts interest from the preparative viewpoint as a simple and convenient route to acyl iodides. Acetyl iodide reacts with phthalic acid, yielding acetic acid and phthalic anhydride, while the reaction of acetyl iodide with oxalic acid leads to formation of acetic acid, carbon(II) oxide, and molecular iodine.

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Chemistry is traditionally divided into organic and inorganic chemistry. The former is the study of compounds containing at least one carbon-hydrogen bonds. 460-37-7, Name is 1,1,1-Trifluoro-3-iodopropane, molecular formula is C3H4F3I, belongs to iodides-buliding-blocks compound, is a common compound. In a patnet, author is Nilsson, M, once mentioned the new application about 460-37-7, Product Details of 460-37-7.

Iodide handling by the thyroid epithelial cell

Iodination of thyroglobulin, the key event in the synthesis of thyroid hormone, is an extracellular process that takes place inside the thyroid follicles at the apical membrane surface that faces the follicular lumen. The supply of iodide involves two steps of TSH-regulated transport, basolateral uptake and apical efflux, that imprint the polarized phenotype of the thyroid cell. Iodide uptake is generated by the sodium/iodide symporter present in the basolateral plasma membrane. A candidate for the apical iodide-permeating mechanism is pendrin, a chloride/iodide transporting protein recently identified in the apical membrane. In physiological conditions, transepithelial iodide transport occurs without intracellular iodination, despite the presence of large amounts of thyroglobulin and thyroperoxidase inside the cells. The reason is that hydrogen peroxide, serving as electron acceptor in iodide-protein binding and normally produced at the apical cell surface, is rapidly degraded by cytosolic glutathione peroxidase once it enters the cells. Iodinated thyroglobulin in the lumen stores not only thyroid hormone but iodine incorporated in iodotyrosine residues as well. After endocytic uptake and degradation of thyroglobulin, intracellular deiodination provides a mechanism for recycling of iodide to participate in the synthesis of new thyroid hormone at the apical cell surface.

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The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Computed Properties of C14H18I3N3O6, 76801-93-9, Name is 5-Amino-N1,N3-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide, SMILES is O=C(NCC(O)CO)C1=C(I)C(N)=C(I)C(C(NCC(O)CO)=O)=C1I, in an article , author is Rillema, JA, once mentioned of 76801-93-9.

Characteristics of the prolactin stimulation of iodide uptake into mouse mammary gland explants

We have recently reported that prolactin (PRL) stimulates iodide uptake into cultured mouse mammary tissues, This effect occurs in both TCA soluble and insoluble tissue fractions, The effect of PRL apparently involves an RNA-DNA-dependent mechanism, since actinomycin D and cyclohexamide abolish the PRL stimulation of iodide uptake and its incorporation into protein, Perchlorate and thiocyanate, inhibitors of the iodide transporter, also abolish the PRL effects on iodide uptake and incorporation. Similarly, propylthiouracil and aminotriazole, inhibitors of peroxidase, abolish both effects of PRL, Finally, the extent of iodide uptake in mammary cells is suppressed by about 50% in sodium-free medium, These studies thus suggest the existence of a sodium-iodide symporter in the mammary gland which has characteristics similar to the iodide transporter in the thyroid gland-that is, It is sodium dependent and is inhibited by perchlorate and thiocyanate, The fact that both iodide transporter inhibitors and peroxidase inhibitors abolish PRL-stimulated iodide uptake and incorporation suggests that there may be a coupled mechanism involving the iodide transporter and the peroxidase enzyme.

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The reaction rate of a catalyzed reaction is faster than the reaction rate of the uncatalyzed reaction at the same temperature. Safety of 1,1,1-Trifluoro-3-iodopropane, 460-37-7, Name is 1,1,1-Trifluoro-3-iodopropane, SMILES is ICCC(F)(F)F, in an article , author is Wu, Shih-Lu, once mentioned of 460-37-7.

Histidine residue at position 226 is critical for iodide uptake activity of human sodium/iodide symporter

The sodium/iodide symporter (SLC5A5; also known as NIS), a transamembrane glycoprotein principally in the thyroid gland, is responsible for the accumulation of iodide necessary for thyroid hormones. Our previous study indicated that a novel exon 6 deletion (residues 233-280) in SLC5A5 loses the iodide uptake activity. Herein we characterized the role of His-226 in iodide transport of SLC5A5. His-226, a highly conserved extracellular residue among SLC5A5 homologs, was replaced with alanine, aspartic acid, glutamic acid, or lysine. All the SLC5A5 mutants were expressed normally in the cells and targeted correctly to the plasma membrane. However, all of the mutants displayed severe defects in iodide uptake, suggesting that His-226 was critical for iodide uptake. Kinetic analysis further showed that mutation at His-226 led to a dramatic decrease in These findings suggested that the decreased levels of iodide uptake activity of SLC5A5 mutants resulted from lower catalytic rates. In Conclusion, our-data first identified the involvement of extracellular charged amino acid residue in the iodide uptake ability of SLC5A5.

But sometimes, even after several years of basic chemistry education, it is not easy to form a clear picture on how they govern reactivity! 460-37-7, you can contact me at any time and look forward to more communication. Safety of 1,1,1-Trifluoro-3-iodopropane.