Synthetic Route of 2468-56-6,Some common heterocyclic compound, 2468-56-6, name is 6-Iodohex-1-yne, molecular formula is C6H9I, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
2-Amino-oct-7-ynoic acid methyl ester hydrochloride was synthesised using the same methods previously reported for the synthesis of 2-Amino-pent-4-ynoic acid methyl ester hydrochloride (Kotha et al., Tetrahedron 2002, 58, 9203-9208). 1H NMR (300 MHz, D2O) delta 4.16 (t, 1H), delta 3.84 (s, 3H), delta 2.35 (t, 1H), delta 2.24 (m, 2H), delta 1.95 (m, 2H), delta 1.52 (m, 4H) ppm; 13C NMR (75 MHz, D2O) delta 170.9, 85.6, 69.6, 53.6, 52.9, 29.3, 27.0, 23.4, 17.3 ppm; HRMS (ESI) calcd for C9H15NO2 (M+) 170.1176, found 170.1171.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 6-Iodohex-1-yne, its application will become more common.
Reference:
Patent; North Carolina State University; US2009/263438; (2009); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com