Day, David Philip; Mora Vargas, Jorge Andres; Burtoloso, Antonio Carlos Bender published an article in 2021. The article was titled 《Direct Synthesis of α-Fluoro-α-Triazol-1-yl Ketones from Sulfoxonium Ylides: A One-Pot Approach》, and you may find the article in Journal of Organic Chemistry.SDS of cas: 1774-47-6 The information in the text is summarized as follows:
The work reported herein showcases a new route to access α-fluoro-α-triazol-1-yl ketones I [R1 = t-Bu, Ph, 2,4,6-tri-ClC6H2, etc.; R2 = t-Bu, Ph, 4-MeC6H4, etc.] from sulfoxonium ylides via α-azido-α-fluoro ketone intermediates. In a one-pot, two-step sequence, the ketosulfoxonium reactant initially underwent insertion of F+ and N3-, followed by a subsequent CuAAC reaction with arylacetylenes to install a 1,4-triazolo moiety. The approach allowed for modification to both the sulfoxonium ylide and arylacetylene reactants. Fifteen examples had been reported, with yields ranging between 22%-75%.Trimethylsulfoxonium iodide(cas: 1774-47-6SDS of cas: 1774-47-6) was used in this study.
Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.SDS of cas: 1774-47-6
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com