In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. COA of Formula: C5H4IN.
Li, Zhaojie;Shen, Jie;Jiang, Qing;Shen, Sheng;Zhou, Jing;Zeng, Huaqiang research published 《 Directionally Aligned Crown Ethers as Superactive Organocatalysts for Transition-metal Ion-free Arylation of Unactivated Arenes》, the research content is summarized as follows. When one-dimensionally aligned to the same side, multiple non-covalently associated crown ether groups could act as a whole to yield a higher catalytic activity than an individual poorly active crown ether group, delivering the lowest catalyst loading of 1-2 mol among all hitherto known organocatalysts for catalyzing direct arylation of inactivated arenes such as benzene, 1,4-difluorobenzene, pyridine and pyrazine with iodoarenes ArI (Ar = Ph, naphthalen-2-yl, thiophen-3-yl, etc.).
COA of Formula: C5H4IN, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.
3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.
3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com