In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. Application In Synthesis of 5029-67-4.
Sardarian, A. R.;Kazemnejadi, M.;Esmaeilpour, M. research published 《 Functionalization of superparamagnetic Fe3O4@SiO2 nanoparticles with a Cu(II) binuclear Schiff base complex as an efficient and reusable nanomagnetic catalyst for N-arylation of α-amino acids and nitrogen-containing heterocycles with aryl halides》, the research content is summarized as follows. Fe3O4@SiO2 nanoparticles was functionalized with a binuclear Schiff base Cu(II)-complex (Fe3O4@SiO2/Schiff base-Cu(II) NPs) and used as an effective magnetic hetereogeneous nanocatalyst for the N-arylation of α-amino acids and nitrogen-containig heterocycles. The catalyst, Fe3O4@SiO2/Schiff base-Cu(II) NPs was characterized by Fourier transform IR (FTIR) and UV-visible (UV-vis) analyses step by step. The structure of Fe3O4 nanoparticles was checked by X-ray diffraction (XRD) technique. Furthermore, the magnetic properties of the nanocatalyst were investigated by vibrating sample magnetometer (VSM) anal. Loading content as well as leaching amounts of copper supported by the catalyst was measured by inductive coupled plasma (ICP) anal. Also, thermal studies of the nanocatalyst was studied by thermal gravimetric anal. (TGA) instrument. XPS anal. of the catalyst revealed that the copper sites are in +2 oxidation state. The Fe3O4@SiO2/Schiff base-Cu(II) complex was found to be an effective catalyst for C-N cross-coupling reactions, which high to excellent yields were achieved for α-amino acids as well as N-hetereocyclic compounds Easy recoverability of the catalyst by an external magnet, reusability up to eight runs without significant loss of activity, and its well stability during the reaction are among the other highlights of this catalyst.
5029-67-4, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., Application In Synthesis of 5029-67-4
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com