Transition metal-free, chemoselective arylation of thioamides yielding aryl thioimidates or N-aryl thioamides was written by Villo, Piret;Kervefors, Gabriella;Olofsson, Berit. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2018.Reference of 139139-80-3 The following contents are mentioned in the article:
A transition metal-free efficient method was developed for the synthesis of aryl thioimidates I [R = n-hexyl, Boc, Bn; R1 = i-Pr, c-hexyl, Ph, etc.; Ar = Ph, 4-MeC6H4, 3-pyridyl, etc.] in good to excellent yields via chemoselective S-arylation of thioamides with diaryliodonium salts under basic conditions. Reactions with thiolactams delivered N-aryl thioamides, e.g., II in good yields at room temperature Equimolar amounts of thioamide, base and diaryliodonium salt were sufficient to obtain a diverse selection of products within short reaction times. This study involved multiple reactions and reactants, such as Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3Reference of 139139-80-3).
Bis(2,4,6-trimethylphenyl)iodonium triflate (cas: 139139-80-3) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. Due to this activity, the indole ring system has become an important component or intermediate in the synthesis of heterocycles.Reference of 139139-80-3
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com