Month: November 2022

McKillop, Alexander published the artcileFurther functional-group oxidations using sodium perborate, Recommanded Product: 3-Iodo-1,2,4,5-tetramethylbenzene, the main research area is sodium perborate oxidant; aldehyde oxidation sodium perborate; iodoarene oxidation sodium perborate; nitrile aromatic oxidation hydration; azine oxidation sodium perborate; sulfur heterocycle oxidation sodium perborate.

Sodium perborate in acetic acid is an effective reagent for the oxidation of aromatic aldehydes to carboxylic acids, iodoarenes to (diacetoxyiodo)arenes, azines to N-oxides, and various types of sulfur heterocycles to S,S-dioxides. Nitriles are unaffected by the reagent in acetic acid, but undergo smooth hydration to amides when aqueous methanol is employed as solvent.

Tetrahedron published new progress about Aromatic nitriles Role: RCT (Reactant), RACT (Reactant or Reagent). 2100-25-6 belongs to class iodides-buliding-blocks, name is 3-Iodo-1,2,4,5-tetramethylbenzene, and the molecular formula is C10H13I, Recommanded Product: 3-Iodo-1,2,4,5-tetramethylbenzene.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Dong, Ziyang published the artcileDual roles of bisphosphines and epoxides: Rh-catalyzed highly chemoselective and diastereoselective (3 + 2) transannulations of 1,2,3-thiadiazoles with cyanoepoxides, Recommanded Product: Ethyl 3-(4-iodophenyl)-3-oxopropanoate, the main research area is cyanoepoxide thiadiaazole rhodium catalyst chemoselective diastereoselective regioselective cycloaddition; oxiranyl isothiazole preparation.

A highly diastereoselective and chemoselective (3 + 2) transannulation of 1,2,3-thiadiazoles with cyanoepoxides was discovered. The use of sterically larger DPEPhos allows the preparation of cis-epoxyl isothiazoles from cis-cyanoepoxides in up to 95% yields and 100 : 0 dr, while the use of sterically smaller DPPF allows the synthesis of trans-products from cis- or trans-cyanoepoxides in up to 95% yields and 100 : 0 dr. Bisphosphines and epoxides play dual roles. Bisphosphines served not only as ligands, but also as catalysts to catalyze the isomerization of cis-epoxides to trans-isomers. The diastereoselectivity was controlled by the kinetic competition between the direct transannulation of cis-cyanoepoxides and the bisphosphine-catalyzed isomerization of cis-products. The epoxy group’s large steric hindrance guarantees excellent chemoselectivity toward the (3 + 2) annulation, and its electron-withdrawing ability significantly improves the reactivity of the adjacent cyano group. To address the controversy over the organorhodium intermediates, this study suggested the resonation between Lee’s umpolung 1,3-dipoles, Bao’s cyclometalated Rh(III) complexes, and thioacyl-coordinated Rh(I) carbenes. Stereospecific access to isothiazole-fused γ-lactone was also developed.

Organic Chemistry Frontiers published new progress about [3+2] Cycloaddition reaction catalysts (chemo and stereoselective). 63131-30-6 belongs to class iodides-buliding-blocks, name is Ethyl 3-(4-iodophenyl)-3-oxopropanoate, and the molecular formula is C11H11IO3, Recommanded Product: Ethyl 3-(4-iodophenyl)-3-oxopropanoate.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Galli, Carlo published the artcileAromatic iodination: evidence of reaction intermediate and of the σ-complex character of the transition state, Related Products of iodides-buliding-blocks, the main research area is aromatic iodination mechanism reaction intermediate; transition state aromatic iodination.

The reactivity of four different procedures of aromatic iodination is compared under the same exptl. conditions, and their selectivity toward two substrates in competition, i.e., mesitylene (I) and durene (II), is evaluated. Two of these procedures, namely, S2O82-/I2 and CeIV/I2, present strong oxidizing capacity. Since the same I/II relative reactivity is obtained from the four procedures, it becomes possible to state that a common reactive intermediate, most likely the I+ ion, is generated. The use of the I/II mechanistic probe suggests the following description of the iodination reaction: electrophilic substitution at the aromatic nucleus, with a transition state properly represented in terms of a σ-complex. The radical cation of II also forms when the iodination is carried out by means of oxidizing agents, but it is solely responsible for the formation of side-chain substitution products and is not involved in the nuclear substitution process.

Journal of Organic Chemistry published new progress about Aromatic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 2100-25-6 belongs to class iodides-buliding-blocks, name is 3-Iodo-1,2,4,5-tetramethylbenzene, and the molecular formula is C10H13I, Related Products of iodides-buliding-blocks.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Kodomari, Mitsuo published the artcileDirect iodination of aromatic compounds with iodine and alumina-supported copper(II) chloride or sulfate, Category: iodides-buliding-blocks, the main research area is iodination aromatic compound iodine; copper chloride sulfate iodination aromatic compound; alumina copper chloride iodination aromatic compound.

The iodination of aromatic compounds (polymethylbenzenes, alkyl Ph ethers, and polynuclear aromatic hydrocarbons) with iodine in combination with copper(II) chloride or sulfate supported on alumina proceeds well under mild conditions to selectively give monoiodinated compounds in high yields.

Bulletin of the Chemical Society of Japan published new progress about Aromatic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 2100-25-6 belongs to class iodides-buliding-blocks, name is 3-Iodo-1,2,4,5-tetramethylbenzene, and the molecular formula is C10H13I, Category: iodides-buliding-blocks.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chaikovskii, V. K. published the artcileIodination of aromatic compounds with iodine monochloride in aqueous sulfuric acid, Application In Synthesis of 2100-25-6, the main research area is iodination aromatic compound iodine chloride; toluene iodination iodine chloride; chemoselectivity iodination aromatic compound iodine chloride; regioselectivity iodination aromatic compound iodine chloride; alkylbenzene iodination iodine chloride; durene iodination iodine chloride; anisole iodination iodine chloride; aniline iodination iodine chloride.

Iodine monochloride in aqueous sulfuric acid turned out to be a convenient and general reagent for preparative iodination of alkylbenzenes, phenol ethers, and aromatic amines. The relative selectivity and activity of iodine monochloride in aqueous solutions of sulfuric acid with various concentrations were determined using toluene as model substrate. Raising the sulfuric acid concentration results in considerable increase of the electrophilicity of ICI. Effective sulfuric acid concentrations were determined for specific substrate series. Iodine monochloride in aqueous sulfuric acid shows enhanced selectivity in the synthesis of monoiodo derivatives

Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii) published new progress about Aromatic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 2100-25-6 belongs to class iodides-buliding-blocks, name is 3-Iodo-1,2,4,5-tetramethylbenzene, and the molecular formula is C10H13I, Application In Synthesis of 2100-25-6.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bedrac, Leon published the artcileIodine(I) Reagents in Hydrochloric Acid-Catalyzed Oxidative Iodination of Aromatic Compounds by Hydrogen Peroxide and Iodine, Product Details of C10H13I, the main research area is iodine hydrochloric acid catalyzed oxidative iodination aromatic compound.

Hydrochloric acid activates the oxidative iodination of aromatic compounds with the iodine- hydrogen peroxide system through the formation of an iodine(I) compound as the iodinating reagent. Activation with hydrochloric acid is more powerful than that with sulfuric acid. The formation of dichloroiodic acid (HICl2) with various forms of hydrogen peroxide was followed using UV spectroscopy. The HICl2 was used as the iodinating reagent. In the preparative oxidative iodinaton of various aromatic compounds, hydrochloric acid was used in a catalytic amount and the iodine(I) reagent was formed in situ with 0.5 equivalent hydrogen peroxide and 0.5 equivalent mol. iodine. Two types of reactivity were observed in oxidative iodination with iodine(I) species catalyzed by hydrochloric acid: in the iodination of anisole better yields of iodination were observed with a smaller amount of hydrochloric acid, while on the contrary 4-tert-butyltoluene gave better yields of iodination upon increasing the amount of hydrochloric acid. Reactivity was further manipulated by the choice of the solvent (MeCN, trifluoroethanol, hexafluoro-2-propanol).

Advanced Synthesis & Catalysis published new progress about Aromatic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 2100-25-6 belongs to class iodides-buliding-blocks, name is 3-Iodo-1,2,4,5-tetramethylbenzene, and the molecular formula is C10H13I, Product Details of C10H13I.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Krasnokutskaya, E. A. published the artcileComparative Study of the Reactivity of Iodinating Agents in Solution and Solid Phase, Synthetic Route of 2100-25-6, the main research area is iodide aromatic preparation iodine iodine chloride iodosuccinimide iodinating agent; aromatic compound iodination solution solid phase; dibenzoylmethane iodination iodosuccinimide iodinating agent.

The results of reactions of a series of aromatic substrates with iodine, iodine(I) chloride, and N-iodosuccinimide in solution and solid phase were compared for the first time. In all cases, the general relations holding in the iodination process were similar. Iodine(I) chloride was found to chlorinate anthracene. A high efficiency of solid-phase iodination of β-diketones was demonstrated using dibenzoylmethane as an example.

Russian Journal of Organic Chemistry published new progress about Aromatic compounds Role: RCT (Reactant), RACT (Reactant or Reagent). 2100-25-6 belongs to class iodides-buliding-blocks, name is 3-Iodo-1,2,4,5-tetramethylbenzene, and the molecular formula is C10H13I, Synthetic Route of 2100-25-6.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Rao, A. Sambashiva published the artcileIsoquinolinium Dichromate and Chlorochromate as Efficient Catalysts for Oxidative Halogenation of Aromatic Compounds Under Acid-Free Conditions, COA of Formula: C6H4INO3, the main research area is bromoarene preparation green chem ultrasound; arene potassium bromide isoquinolinium dichromate chlorochromate catalyst regioselective bromination; iodoarene preparation green chem ultrasound; potassium iodide arene isoquinolinium dichromate chlorochromate catalyst regioselective iodination.

Isoquinolinium dichromate and isoquinolinium chlorochromate were found as efficient catalysts to trigger oxidative bromination and iodination of aromatic hydrocarbons with KBr/KI and KHSO4 under acid-free conditions. Reaction times reduced highly significantly under sonication, followed by corresponding mono bromo derivatives in very good yield with high regioselectivity.

Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry published new progress about Aldehydes, halo Role: SPN (Synthetic Preparation), PREP (Preparation). 21784-73-6 belongs to class iodides-buliding-blocks, name is 4-Iodo-2-nitrophenol, and the molecular formula is C6H4INO3, COA of Formula: C6H4INO3.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Yusubov, Mekhman S. published the artcilePotassium 4-Iodylbenzenesulfonate: Preparation, Structure, and Application as a Reagent for Oxidative Iodination of Arenes, HPLC of Formula: 2100-25-6, the main research area is potassium iodylbenzenesulfonate preparation arene oxidant.

A new hypervalent iodine(V) compound, potassium 4-iodylbenzenesulfonate, was prepared by the oxidation of 4-iodobenzensulfonic acid with Oxone in water. This potassium salt can be further converted into 4-iodylbenzenesulfonic acid by treatment with the acidic form of Amberlyst 15 in water. A single-crystal X-ray structure of potassium 4-iodylbenzenesulfonate revealed the presence of polymeric chains in the solid state due to a combination of numerous intra- and intermol. interactions. Potassium 4-iodylbenzenesulfonate will likely find many practical applications as a thermally stable and water-soluble hypervalent iodine-based oxidant, particularly useful as a reagent for oxidative iodination of aromatic substrates. This reagent can be effectively recovered from the reaction mixture (92 % recovery) by treatment of the aqueous layer with Oxone at 60°C for 2 h, followed by filtration of the precipitate

European Journal of Organic Chemistry published new progress about Aromatic hydrocarbons Role: RCT (Reactant), RACT (Reactant or Reagent). 2100-25-6 belongs to class iodides-buliding-blocks, name is 3-Iodo-1,2,4,5-tetramethylbenzene, and the molecular formula is C10H13I, HPLC of Formula: 2100-25-6.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Alexander, Varughese M. published the artcileSolvent-free iodination of arenes at room temperature, Recommanded Product: 3-Iodo-1,2,4,5-tetramethylbenzene, the main research area is arene solventless iodination iodine silica supported bismuth nitrate catalyst; aryl iodide preparation.

Silica supported bismuth(III)nitrate pentahydrate (BNP-SiO2) was prepared under simple co-grinding condition. The iodination of aromatic compounds using BNP-SiO2 and mol. iodine under solvent-free conditions is described. The reaction occurred in the solid state at room temperature, yielding the corresponding mono-iodo derivative in good yields. However, less activated aromatics required longer reaction time with comparatively less yield.

Synlett published new progress about Aromatic hydrocarbons Role: RCT (Reactant), RACT (Reactant or Reagent). 2100-25-6 belongs to class iodides-buliding-blocks, name is 3-Iodo-1,2,4,5-tetramethylbenzene, and the molecular formula is C10H13I, Recommanded Product: 3-Iodo-1,2,4,5-tetramethylbenzene.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com