A Novel Approach to Access Aryl Iodides and Disulfides via Dehydrazination of Arylhydrazines and Arylsulfonylhydrazides was written by Balgotra, Shilpi;Kumar Verma, Praveen;Kour, Jaspreet;Gupta, Sorav;Vishwakarma, Ram A.;Sawant, Sanghapal D.. And the article was included in ChemistrySelect in 2018.Safety of 4-Iodo-1,2-dimethoxybenzene This article mentions the following:
The direct iodination of arylhydrazines was achieved using I2 and KOAc in excellent yields. In addition, disulfides were synthesized from arylsulfonylhydrazides in high yields using same catalytic system. The advantageous feature of the present protocol is the exclusion of transition metal catalyst from the reaction for dehydrazination. A number of labile functionalities remain intact during the reaction. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Safety of 4-Iodo-1,2-dimethoxybenzene).
4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.Safety of 4-Iodo-1,2-dimethoxybenzene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com