Breuning, Matthias et al. published their research in Chemistry – A European Journal in 2009 | CAS: 10297-05-9

1-Chloro-4-iodobutane (cas: 10297-05-9) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Product Details of 10297-05-9

Chiral 2-endo-Substituted 9-Oxabispidines: Novel Ligands for Enantioselective Copper(II)-Catalyzed Henry Reactions was written by Breuning, Matthias;Hein, David;Steiner, Melanie;Gessner, Viktoria H.;Strohmann, Carsten. And the article was included in Chemistry – A European Journal in 2009.Product Details of 10297-05-9 This article mentions the following:

A flexible approach, applicable on a gram scale, to chiral 2-endo-substituted 9-oxabispidines I [R1 = Et, i-Pr, cyclohexyl, Ph, R2 = Me; R1R2 = (CH2)4] was developed. The key intermediate, a cis-configured 6-aminomethylmorpholine-2-carbonitrile II, was prepared from (R)-3-aminopropane-1,2-diol and 2-chloroacrylonitrile. The 2-endo substituent was introduced by Grignard addition, cyclization, and exo-selective reduction, thus furnishing the enantiomerically pure bi- and tricyclic 9-oxabispidines I in 19-59% yields. The CuCl2 complex of the tricyclic 9-oxabispidine I [R1R2 = (CH2)4], which carries an 2-endo,N-annelated piperidine ring, is an excellent catalyst for enantioselective Henry reactions of aldehydes R3CHO (R3 = i-Bu, n-octyl, Ph, 4-O2NC6H4, etc.) with nitromethane giving the S-configured β-nitro alcs. R3CH(OH)CH2NO2 in 91-98% ee (13 examples). Surprisingly, the analogous copper complexes of the bicyclic 9-oxabispidines I (R2 = Me) delivered the enantiocomplementary R-configured products in 33-57% ee. The resp. transition states were discussed. In the experiment, the researchers used many compounds, for example, 1-Chloro-4-iodobutane (cas: 10297-05-9Product Details of 10297-05-9).

1-Chloro-4-iodobutane (cas: 10297-05-9) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Product Details of 10297-05-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com