Ligand-enabled β-C-H arylation of α-amino acids without installing exogenous directing groups was written by Chen, Gang;Zhuang, Zhe;Li, Gen-Cheng;Saint-Denis, Tyler G.;Hsiao, Yi;Joe, Candice L.;Yu, Jin-Quan. And the article was included in Angewandte Chemie, International Edition in 2017.Application In Synthesis of 4-Iodo-1,2-dimethoxybenzene This article mentions the following:
Herein we report acid-directed β-C(sp3)-H arylation of α-amino acids enabled by pyridine-type ligands. This reaction does not require the installation of an exogenous directing group, is scalable, and enables the preparation of Fmoc-protected (Fmoc = 9-fluorenylmethoxycarbonyl) unnatural amino acids in three steps. The pyridine-type ligands are crucial for the development of this new C(sp3)-H arylation. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Application In Synthesis of 4-Iodo-1,2-dimethoxybenzene).
4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Application In Synthesis of 4-Iodo-1,2-dimethoxybenzene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com