Month: January 2023

Octopolar Chromophores Based on Donor- and Acceptor-Substituted 1,3,5-Tris(phenylethynyl)benzenes: Impact of meta-Conjugation on the Molecular and Electronic Structure by Means of Spectroscopy and Theory was written by Moreno Oliva, Maria;Casado, Juan;Hennrich, Gunther;Lopez Navarrete, Juan T.. And the article was included in Journal of Physical Chemistry B in 2006.Application of 3268-21-1 This article mentions the following:

The mol. and electronic structures of all-meta-substituted phenylacetylene mesitylenes peripherally substituted with donor or acceptor (D-A) groups are studied. The impact of meta- and para-substitution patterns is also analyzed by employing Raman and optical spectroscopies in conjunction with theor. calculations Outer Ph rings display a partial quinoid character induced by two different motifs: (i) outer phenyls â†?triple bond charge transfer for the cases where these phenyls are substituted with electron-donors; (ii) double electron withdrawing effect in the mols. with the peripheral phenyls substituted with electron acceptors. A moderate tuning of the optical gap is observed in agreement with the partial blockade of π-electron conjugation exerted by the meta disposition. The orbital structure of the compounds partially preserves that of the mesitylene group showing extra-conjugation due to the addition of the arms, so that conjugation is not entirely obstructed but partially impeded in the ground electronic state (i.e., electron occupied orbitals). As for the excited states, the low-lying energy empty orbitals offer better conditions for full conjugation over the whole mol. scaffold. Interesting optical properties such as overlapping centers along the lowest energy optical excitations and enhanced optical transparency with importance for the application of these materials in optoelectronics were justified from the electronic structure. A greater degree of quinoidization, and more allowed π-electron delocalization, over the entire mol. is recognized in the case of linear phenylacetylenes substituting in para positions the central core. In the experiment, the researchers used many compounds, for example, 1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1Application of 3268-21-1).

1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Application of 3268-21-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

New Indolo[3,2-b]indole based small organic molecules for Organic Thin Film Transistors (OTFTs): A combined experimental and DFT Study was written by Puli, Venkat Swamy;Subburu, Mahesh;Bhongiri, Yadagiri;Tripathi, Anuj;Prasad, K. R. S.;Chatterjee, Anindita;Pola, Someshwar;Chetti, Prabhakar. And the article was included in Journal of Molecular Structure in 2021.Application of 220185-63-7 This article mentions the following:

Synthesis of new indolo[3,2-b]indoles in presence of Ag-doped ZnO and (Diacetoxyiodo) benzene system under visible-light were reported. All the new fused linear heterocyclic indolo[3,2-b]indole systems thoroughly characterized by spectroscopic methods like mass, UV-visible, NMR and C, H, N elemental anal. Further, their photophys. properties were carried out by combined exptl. and theor. studies. Thermogravimetric studies were carried out to confirm the thermal stability of mols. The frontier MOs of mols. were characterized with the help of cyclic voltammetry. Addnl., the compounds of series 5 were used for the fabrication of organic thin-film transistors, which indicated the hole mobilities in the range of 0.11 – 0.85 cm²/Vs and with on/off ratio 10⁵ on ODTS-SiO₂ substrate at 50°C and are also supported by DFT studies. In the experiment, the researchers used many compounds, for example, 4,5-Dichloro-2-iodoaniline (cas: 220185-63-7Application of 220185-63-7).

4,5-Dichloro-2-iodoaniline (cas: 220185-63-7) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.Application of 220185-63-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Palladium-catalyzed enantioselective C(sp²)-H arylation of ferrocenyl ketones enabled by a chiral transient directing group was written by Xu, Jiancong;Liu, Yang;Zhang, Jinling;Xu, Xiaohua;Jin, Zhong. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2018.Electric Literature of C11H14INO This article mentions the following:

Palladium-catalyzed enantioselective C(sp²)-H activation of ferrocenyl ketones is achieved through utilizing catalytic, inexpensive L-tert-leucine as a chiral transient directing group. The transformation allows rapid access to ferrocene scaffolds simultaneously possessing planar- and stereogenic central chirality, widely applied in the ferrocene-based chiral ligand families. In the experiment, the researchers used many compounds, for example, N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8Electric Literature of C11H14INO).

N,N-Diethyl-4-iodobenzamide (cas: 77350-52-8) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Electric Literature of C11H14INO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Selective PPARδ Modulators Improve Mitochondrial Function: Potential Treatment for Duchenne Muscular Dystrophy (DMD) was written by Lagu, Bharat;Kluge, Arthur F.;Tozzo, Effie;Fredenburg, Ross;Bell, Eric L.;Goddeeris, Matthew M.;Dwyer, Peter;Basinski, Andrew;Senaiar, Ramesh S.;Jaleel, Mahaboobi;Tiwari, Nirbhay Kumar;Panigrahi, Sunil K.;Krishnamurthy, Narasimha Rao;Takahashi, Taisuke;Patane, Michael A.. And the article was included in ACS Medicinal Chemistry Letters in 2018.Recommanded Product: 15813-09-9 This article mentions the following:

Arylheterocyclylmethylphenoxyalkanoic and -alkenoic acids such as I were prepared as selective activators of PPARδ for potential use in improving mitochondrial function and for treatment of Duchenne muscular dystrophy (DMD); the heterocyclyl moiety was designed to mimic the cis-amide conformation found in the crystal structure of a previously prepared PPARδ activator to the ligand binding domain of PPARδ. The activation of PPARδ, selectivities for PPARδ over PPARα and PPARγ, and pharmacokinetics (half-lives, clearance, and AUC) in mice were determined for the compounds I (MA-0204) was a potent, selective PPARδ modulator with good pharmacokinetic properties. I was tested in vivo in mice and in myoblasts isolated from a DMD patient; I altered the expression of PPARδ target genes and improved fatty acid oxidation, indicating that I may be useful for treating DMD. In the experiment, the researchers used many compounds, for example, 4,5-Diiodo-1H-imidazole (cas: 15813-09-9Recommanded Product: 15813-09-9).

4,5-Diiodo-1H-imidazole (cas: 15813-09-9) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Recommanded Product: 15813-09-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Synthesis of diaryl ethers from tyrosine derivatives was written by Crimmin, Michael J.;Brown, Allan G.. And the article was included in Tetrahedron Letters in 1990.Related Products of 2314-37-6 This article mentions the following:

Diaryl ethers of tyrosine, maintaining optical activity, have been formed through the reaction of a tyrosine derivative with an aryl iodonium salt. Thus, iodonium salt I was treated with tyrosine derivative II in refluxing DMF to give 59% ether III. In the experiment, the researchers used many compounds, for example, 3-Iodo-4-methoxybenzaldehyde (cas: 2314-37-6Related Products of 2314-37-6).

3-Iodo-4-methoxybenzaldehyde (cas: 2314-37-6) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I. This periodic order also follows the atomic radius of halogens and the length of the carbon-halogen bond.Related Products of 2314-37-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Deoxygenative Arylation of Carboxylic Acids by Aryl Migration was written by Ruzi, Rehanguli;Ma, Junyang;Yuan, Xiang-Ai;Wang, Wenliang;Wang, Shanshan;Zhang, Muliang;Dai, Jie;Xie, Jin;Zhu, Chengjian. And the article was included in Chemistry – A European Journal in 2019.Application of 20776-54-9 This article mentions the following:

An unprecedented deoxygenative arylation of aromatic carboxylic acids was achieved, allowing the construction of an enhanced library of unsym. diaryl ketones. The synergistic photoredox catalysis and phosphoranyl radical chem. allows for precise cleavage of a stronger C-O bond and formation of a weaker C-C bond by 1,5-aryl migration under mild reaction conditions. This new protocol was independent of substrate redox-potential, electronic, and substituent effects. It afforded a general and promising access to 60 examples of synthetically versatile o-amino and o-hydroxy diaryl ketones under redox-neutral conditions. Furthermore, it also brings one concise route to the total synthesis of quinolone alkaloid, (±)-yaequinolone A2, and a viridicatin derivative in satisfying yields. In the experiment, the researchers used many compounds, for example, 2-Amino-4-iodobenzoic acid (cas: 20776-54-9Application of 20776-54-9).

2-Amino-4-iodobenzoic acid (cas: 20776-54-9) belongs to iodide derivatives. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I. This periodic order also follows the atomic radius of halogens and the length of the carbon-halogen bond.Application of 20776-54-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Encapsulation of polyoxotungstate into dendrimers by ionic bonding and their use as oxidation catalyst was written by Jahier, Claire;Plault, Lauriane;Nlate, Sylvain. And the article was included in Israel Journal of Chemistry in 2009.Related Products of 10297-05-9 This article mentions the following:

A family of 36-armed dendrimers containing six internal amino groups was synthesized and used to incorporate polyoxometalates (POMs) into their structures by ionic bonding. Allyl-terminated dendrimer 17 (with oxidizable end groups) and methylphenyl-terminated dendrimer 18 (with non-oxidizable end groups) were used for these studies. It was found that the electrostatic incorporation of the tri-anionic POM [PO₄{WO(O₂)₂}₄]^3- into the methylphenyl-terminated dendrimer 18, in an acidic medium, leads to the dendritic POM hybrid 19, bearing two POM units in its structure. In contrast, attempts to encapsulate POMs into allyl-terminated dendrimer 17 gave unsatisfactory results. Indeed, the epoxidation kinetics of the 36-olefinic terminated dendrimer 17 was too slow, and the expected 36-epoxy-dendritic POM framework 20 was not obtained. Lengthening the reaction up to six hours led to the decomposition of POM species. The solubility in organic solvents of the dendritic POM hybrid 19, combined with its NMR and IR data, indicate that POM units are clearly connected to the dendritic structure. The catalytic performance of this hybrid material in the oxidation of cyclooctene shows that the properties of POM are retained. The POM-encapsulated dendrimer 19 was found to be an effective catalyst in the oxidation of cyclooctene. In the experiment, the researchers used many compounds, for example, 1-Chloro-4-iodobutane (cas: 10297-05-9Related Products of 10297-05-9).

1-Chloro-4-iodobutane (cas: 10297-05-9) belongs to iodide derivatives. Organic iodides are widely used in organic synthesis. Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Related Products of 10297-05-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Palladium Nanoparticle-Catalyzed Stereoselective Domino Synthesis of All-Carbon Tetrasubstituted Olefin Containing Oxindoles via Carbopalladation/C-H Activation was written by Parveen, Naziya;Sekar, Govindasamy. And the article was included in Journal of Organic Chemistry in 2020.SDS of cas: 5460-32-2 This article mentions the following:

The binaphthyl stabilized palladium nanoparticles (Pd-BNP) catalyzed single-step, stereoselective domino synthesis of sym. and unsym. all-carbon tetrasubstituted olefin containing oxindoles from readily accessible anilides has been developed. The Pd-BNP catalyst showed a wide range of functional group tolerance that enabled building a library of heteroaromatics This reusable Pd catalyst reflected its utility in the synthesis of biol. important AMP-activated protein kinase deprived of any metal Pd contamination. The nanocatalyst was easily recovered and reused five times without any appreciable loss in particle size or catalytic activity. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2SDS of cas: 5460-32-2).

4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.SDS of cas: 5460-32-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

TosMIC and its derivatives as versatile sulfonylating agents for the synthesis of p-toluenesulfonylarenes from aryl halides and arylboronic acids was written by Ravi Kumar, G.;Ramesh, B.;Banik, Swarnayu;Subba Reddy, B. V.. And the article was included in Tetrahedron in 2020.HPLC of Formula: 5460-32-2 This article mentions the following:

An efficient copper(II) catalyzed sulfonyation of aryl halides had been achieved using TosMIC (p-toluenesulfonylmethyl isocyanide) as a sulfonylating agent. This newly developed sulfonylation approach provided an easy access for the synthesis of diaryl sulfones I [Ar = Ph, 4-MeOC₆H₄, 2-pyridyl, etc.] from aryl bromides, iodides and boronic acids with TosMIC under neutral conditions. This method was useful for the sulfonylation of aryl boronic acids under similar conditions. This was the first report on the sulfonylation of aryl bromides, iodides and boronic acids using TosMIC. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2HPLC of Formula: 5460-32-2).

4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.HPLC of Formula: 5460-32-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

New methods of imidazole functionalization – from imidazole to marine alkaloids was written by Du, Hongwang;He, Yong;Rasapalli, Sivappa;Lovely, Carl J.. And the article was included in Synlett in 2006.Application In Synthesis of 4,5-Diiodo-1H-imidazole This article mentions the following:

The pyrrole-imidazole family of marine alkaloids, the so-called oroidin natural products, exhibits an impressive diversity of structural motifs. The majority of these natural products contain one or more imidazole moieties intricately embedded within a polycyclic framework and thus present significant challenges to extant synthetic methods. Our approach to this problem has centered on the development of methods for the elaboration of simple imidazoles. This review describes the results of these efforts leading to the development of a variety of methods, including cycloadditions, oxidative and transition-metal-catalyzed reactions (e.g., with π-allylpalladium). In the experiment, the researchers used many compounds, for example, 4,5-Diiodo-1H-imidazole (cas: 15813-09-9Application In Synthesis of 4,5-Diiodo-1H-imidazole).

4,5-Diiodo-1H-imidazole (cas: 15813-09-9) belongs to iodide derivatives. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.Application In Synthesis of 4,5-Diiodo-1H-imidazole

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com