Recommanded Product: (2S)-(+)-3-Chloropropane-1,2-diol. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: (2S)-(+)-3-Chloropropane-1,2-diol, is researched, Molecular C3H7ClO2, CAS is 60827-45-4, about The antiglycolytic action of (S)-α-chlorohydrin on epididymal bovine spermatozoa in vitro. Author is Jones, A. R.; Du Toit, J. I..
(S)-α-Chlorohydrin [60827-45-4] interferes with glycolysis in bovine spermatozoa, whereas the (R)-isomer is ineffective. The action of the (S)-isomer, which involves inhibition of the reaction catalyzed by glyceraldehyde-3-phosphate dehydrogenase [9001-50-7], is not immediate but is evident only after a brief period of incubation with the spermatozoa. This inhibitory action is prevented when glycerol [56-81-5] is present, suggesting that the mechanism of action of (S)-α-chlorohydrin requires its oxidation to (S)-3-chlorolactaldehyde [86747-03-7], which is the active metabolite. Addition of (R,S)-3-chlorolactaldehyde [84709-24-0] to bovine spermatozoa caused immediate inhibition of glycolysis. The action of (S)-α-chlorohydrin in bovine spermatozoa may be similar to that observed in the spermatozoa of other species in being a 2-stage process: 1st, its oxidation to (S)-3-chlorolactaldehyde, and then inhibition of the glycolytic enzyme by this metabolite.
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Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com