Safety of (2S)-(+)-3-Chloropropane-1,2-diol. The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: (2S)-(+)-3-Chloropropane-1,2-diol, is researched, Molecular C3H7ClO2, CAS is 60827-45-4, about Inhibition of fructolytic enzymes in boar spermatozoa by (S)-α-chlorohydrin and 1-chloro-3-hydroxypropanone. Author is Jones, A. R.; Bubb, W. A.; Murdoch, S. R.; Stevenson, D. A..
When boar spermatozoa were incubated with (S)-α-chlorohydrin [60827-45-4], glyceraldehyde-3-phosphate dehydrogenase (GPD) [9001-50-7] activity was inhibited. The (R)-isomer had no effect whereas (R,S)-3-chlorolactaldehyde [84709-24-0] also inhibited GDP and lactate dehydrogenase [9001-60-9]. The in vitro production of (S)-3-chlorolactaldehyde [86747-03-7], the active metabolite of (S)-α-chlorohydrin, was attempted by incubating boar spermatozoa with 1-chloro-3-hydroxypropanone [24423-98-1]. Preliminary results indicated that this compound is converted into (S)-3-chlorolactaldehyde as well as to another metabolite which is an inhibitor of other enzymes within the fructolytic pathway.
Here is just a brief introduction to this compound(60827-45-4)Safety of (2S)-(+)-3-Chloropropane-1,2-diol, more information about the compound((2S)-(+)-3-Chloropropane-1,2-diol) is in the article, you can click the link below.
Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com