The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: (2S)-(+)-3-Chloropropane-1,2-diol, is researched, Molecular C3H7ClO2, CAS is 60827-45-4, about Activities of various 6-chloro-6-deoxysugars and (S)α-chlorohydrin in producing spermatocoeles in rats and paralysis in mice and in inhibiting glucose metabolism in bull spermatozoa in vitro, the main research direction is contraceptive male chlorodeoxy sugar; chlorohydrin male contraceptive; toxicity male contraceptive chlorodeoxysugar.Synthetic Route of C3H7ClO2.
6-chloro-6-deoxyglucose (I) [40656-44-8], 6-chloro-6-deoxymannose [4990-81-2], 6-chloro-6-deoxyfructose [66451-66-9], 6-chloro-6-deoxyglucitol [76986-26-0], 6-chloro-6-deoxygalactose [18465-32-2], and (S)α-chlorohydrin [60827-45-4] all produced spermatoceles in the efferent ducts and epididymis of the rat and were neurotoxic in the mouse, but only α-chlorohydrin caused substantial inhibition of D-glucose [50-99-7] metabolism in bull spermatozoa in vitro. The relative potencies of the compounds in producing spermatoceles reflected their activities as reversible antifertility agents in the rat but compared to the others 6-chloro-6-deoxymannose was considerably less neurotoxic to mice than might have been anticipated from its contraceptive dose. Thus, different metabolites may be responsible for causing the antifertility and the neurotoxic effects.
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Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com