In 2019,Organic & Biomolecular Chemistry included an article by Li, Tongyu; Liu, Chang; Wu, Shaonan; Chen, Chen; Zhu, Bolin. Category: iodides-buliding-blocks. The article was titled 《Rhodium(III)-catalyzed unreactive C(sp3)-H alkenylation of N-alkyl-1H-pyrazoles with alkynes》. The information in the text is summarized as follows:
The first example of pyrazole-directed rhodium(III)-catalyzed unreactive C(sp3)-H alkenylation with alkynes has been described, which showed a relatively broad substrate scope with good functional group compatibility. Moreover, authors demonstrated that the transitive coordinating center pyrazole could be easily removed under mild conditions. In addition to this study using 1-Chloro-3-iodobenzene, there are many other studies that have used 1-Chloro-3-iodobenzene(cas: 625-99-0Category: iodides-buliding-blocks) was used in this study.
1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Category: iodides-buliding-blocks Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com