The author of 《Synthesis of α-heterosubstituted ketones through sulfur mediated difunctionalization of internal alkynes》 were Zhang, Zhong; Luo, Yuzheng; Du, Hongguang; Xu, Jiaxi; Li, Pingfan. And the article was published in Chemical Science in 2019. Computed Properties of C6H4ClI The author mentioned the following in the article:
Synthesis of α-heterosubstituted ketones was achieved through sulfur mediated difunctionalization of internal alkynes in one-pot. The reaction design involved Ph substituted internal alkyne attacking triflic anhydride activated di-Ph sulfoxide to give a sulfonium vinyl triflate intermediate hydrolysis to give an α-sulfonium ketone and then substitution with various nucleophiles. This method provided a unified route to accessed α-amino ketones, α-acyloxy ketones, α-thio ketones, α-halo ketones, α-hydroxy ketones and related heterocyclic structures in a rapid fashion. The results came from multiple reactions, including the reaction of 1-Chloro-3-iodobenzene(cas: 625-99-0Computed Properties of C6H4ClI)
1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine.Computed Properties of C6H4ClI In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com