In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine.Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Application In Synthesis of 1120-90-7.
Meng, Qi;Zhang, Lian;Zhu, Xinhui;Teng, Qiaoqiao research published 《 Synthesis of 9-O-Arylated Berberine with a Polystyrene Resin Supported Copper(II) Catalyst》, the research content is summarized as follows. A series of polyfluorobenzene, pyridine and aniline substituted berberine derivatives I (Ar = Ph, 4-H2NC6H4, 3-pyridyl, etc.) were prepared via resin-supported Cu(II) catalyzed cross-coupling reactions of tetrahydroberberrubine with iodoarenes and subsequent I2 oxidation The best catalyst, a polyethyleneimine functionalized polystyrene supported Cu2+ (PSAPA·Cu(II)), could be reused for at least 5 runs without significant loss of catalytic activity. Comparative studies on the morphol. and porous structures of the materials suggested a catalyst with a moderate sp. surface area and larger pore diameters was more active in catalyzing the cross-coupling reactions.
1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.
3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.
3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., Application In Synthesis of 1120-90-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com