Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 626-01-7, formula is C6H6IN, Name is 3-Iodoaniline.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. Quality Control of 626-01-7.
Saul, Sirle;Huang, Pei-Tzu;Einav, Shirit;Asquith, Christopher R. M. research published 《 Identification and evaluation of 4-anilinoquin(az)olines as potent inhibitors of both dengue virus (DENV) and Venezuelan equine encephalitis virus (VEEV)》, the research content is summarized as follows. There is an urgent need for novel strategies for the treatment of emerging arthropod-borne viral infections, including those caused by dengue virus (DENV) and Venezuelan equine encephalitis virus (VEEV). We prepared and screened focused libraries of 4-anilinoquinolines and 4-anilinoquinazolines for antiviral activity and identified three potent compounds N-(2,5-dimethoxyphenyl)-6-(trifluoromethyl)quinolin-4-amine (10, I) inhibited DENV infection with an EC50 = 0.25μM, N-(3,4-dichlorophenyl)-6-(trifluoromethyl)quinolin-4-amine (27, II) inhibited VEEV with an EC50 = 0.50μM, while N-(3-ethynyl-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine (54, III) inhibited VEEV with an EC50 = 0.60μM. These series of compounds demonstrated nearly no toxicity with CC50 values greater than 10μM in all cases. These promising results provide a future prospective to develop a clin. compound against these emerging viral threats.
626-01-7, 3-Iodoaniline is a useful research compound. Its molecular formula is C6H6IN and its molecular weight is 219.02 g/mol. The purity is usually 95%.
3-Iodoaniline is a fatty acid that is used in analytical methods to measure the concentration of human serum in blood. It can be used to estimate the population growth rate, with a half-life of about 13 hours. 3-Iodoaniline reacts with hydrogen bond and proton to form a reaction solution, which can be catalyzed by palladium-catalyzed coupling and suzuki coupling reactions. The activation energies for these reactions are typically in the range of 4-8 kcal/mol. The chemical ionization technique is a type of mass spectrometry that is used to determine kinetic data for this compound. Hydrochloric acid can be added as an acid catalyst to increase the rate of reaction and generate more accurate kinetic data., Quality Control of 626-01-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com