Utilization of Copper-Catalyzed Carboarylation-Ring Closure for the Synthesis of New Oxazoline Derivatives was written by Sinai, Adam;Vangel, Dora;Gati, Tamas;Bombicz, Petra;Novak, Zoltan. And the article was included in Organic Letters in 2015.Category: iodides-buliding-blocks The following contents are mentioned in the article:
A copper-catalyzed carboarylation-ring closure strategy was used for the modular synthesis of oxazolines via the reaction of 1-aryl- and 1-alkylpropargylamides and diaryliodonium salts. The novel approach enables the efficient, modular synthesis of oxazoline derivatives bearing fully substituted exo double bonds. E.g., in presence of CuCl in EtOAc at 50 °C, carboarylation-ring closure of N-(3-(2-methylphenyl)prop-2-ynyl)pivalamide with mesityl(phenyl)iodonium trifluoromethanesulfonate gave 76.0% (E)-2-tert-butyl-5-(phenyl(o-tolyl)methylene)-4,5-dihydrooxazole (I). This study involved multiple reactions and reactants, such as Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4Category: iodides-buliding-blocks).
Mesityl(p-tolyl)iodonium trifluoromethanesulfonate (cas: 1204518-02-4) belongs to iodide derivatives. Indole, first isolated in 1866, and it is commonly synthesized from phenylhydrazine and pyruvic acid, although several other procedures have been discovered. Indole plays a fundamental role for QS in E. coli, being one of the signal molecules responsible for the transcription of a variety of genes (gabT, and tnaB ASTD). Category: iodides-buliding-blocks
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com