Synthesis of hybrid acetogenins, α,β-unsaturated-γ-lactone-free nitrogen-containing heterocyclic analogues, and their cytotoxicity against human cancer cell lines was written by Kojima, Naoto;Fushimi, Tetsuya;Maezaki, Naoyoshi;Tanaka, Tetsuaki;Yamori, Takao. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2008.Related Products of 34091-51-5 This article mentions the following:
A series of α,β-unsaturated-γ-lactone-free nitrogen-containing heterocyclic analogs of solamin, a natural mono-THF acetogenin, have been synthesized and their cytotoxicity was investigated against 39 tumor cell lines. One of them, 1-methylpyrazol-5-yl derivative I, showed selective increase of cytotoxicity against NCI-H23 with 80 times higher potency than solamin. In the experiment, the researchers used many compounds, for example, 5-Iodo-1-methyl-1H-pyrazole (cas: 34091-51-5Related Products of 34091-51-5).
5-Iodo-1-methyl-1H-pyrazole (cas: 34091-51-5) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Related Products of 34091-51-5
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com