Microwave assisted domino Heck cyclization and alkynylation: synthesis of alkyne substituted dihydrobenzofurans was written by Karu, Ramesh;Gedu, Satyanarayana. And the article was included in Green Chemistry in 2018.Quality Control of 4-Bromo-2-iodophenol This article mentions the following:
Microwave assisted domino intramol. Heck and Sonogashira coupling for the efficient synthesis of alkyne substituted dihydrobenzofurans is presented. Interestingly, the strategy showed broad substrate scope and was successful with protecting group free functionalities of acetylenes. Gratifyingly, all products were obtained, in excellent to near quant. yields, in a short span of time. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-iodophenol (cas: 207115-22-8Quality Control of 4-Bromo-2-iodophenol).
4-Bromo-2-iodophenol (cas: 207115-22-8) belongs to iodide derivatives. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Quality Control of 4-Bromo-2-iodophenol
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com