Synthesis of δ,δ-Diaryl-α-cyanoacrylamides and δ,δ-Diarylallylidiene Malononitriles by Pd(OAc)2 Catalyzed Mizoroki-Heck Reaction was written by Sengupta, Ayon;Sarkar, Piyali;Maity, Suvendu;Basu, Soumyadip;Ghosh, Prasanta;Rudra, Sonali;Mukhopadhyay, Chhanda. And the article was included in ChemistrySelect in 2021.Category: iodides-buliding-blocks This article mentions the following:
An expeditious route for the stereoselective catalytic monohydration of nitrile and ‘CN’ directed regio-stereoselctive δ-arylation of various arylallylidene malononitriles affording δ, δ-Diaryl-α-cyanoacrylamides in hydrolysis condition and δ, δ-Diarylallylidene malononitriles in anhydrous condition by Pd(OAc)2 catalyzed Mizoriki-Heck reaction was described. This provides an instantaneous formation of a library of compounds in a very short time period and simple operational process. The structure elucidation of the diastereomers was done by HMBC, HSQC, 2-D NMR experiments and X-ray single crystallog. anal. A probable reaction mechanism directed by nitriles and involvement of syn and anti π-allylic Pd-complexes was proposed that is in consonance with the exptl. findings and product distributions. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Category: iodides-buliding-blocks).
4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Iodide-containing intermediates are common in organic synthesis, because of the easy formation and cleavage of the C–I bond. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Category: iodides-buliding-blocks
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com