Difluorocarbene-Based Cyanation of Aryl Iodides was written by Zhang, Yin-Xiang;Xiao, Xuan;Fu, Zhi-Hong;Lin, Jin-Hong;Guo, Yu;Yao, Xu;Cao, Yu-Cai;Du, Ruo-Bing;Zheng, Xing;Xiao, Ji-Chang. And the article was included in Synlett in 2020.Quality Control of 3-Iodobenzo[b]thiophene This article mentions the following:
Herein, a difluorocarbene-based cyanation of aryl iodides promoted by a cheap copper source, Cu(NO3)2ยท2.5H2O, under an air atm is reported. Difluoromethylene phosphobetaine (Ph3P+CF2CO2–), an easily available and shelf-stable difluorocarbene reagent, and NaNH2 are used as the carbon source and the nitrogen source for the nitrile group, resp. The cyanation protocol is attractive because no toxic reagent is used and performing the reactions under an air atm. is operationally convenient. In the experiment, the researchers used many compounds, for example, 3-Iodobenzo[b]thiophene (cas: 36748-88-6Quality Control of 3-Iodobenzo[b]thiophene).
3-Iodobenzo[b]thiophene (cas: 36748-88-6) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Quality Control of 3-Iodobenzo[b]thiophene
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com