In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. Name: 3-Iodopyridine.
Paul, Sudeep;Joy, Bony P.;Sasikala, Geethu;Raghuthaman, Advaya G.;Gudimetla, Vittal B. research published 《 Copper-NHC Based Ullmann Catalysis In Water For Selective N-Arylation Of 3-Aminophenols》, the research content is summarized as follows. This work elucidated synthesis of diarylamines RNHR1 [R = 3-OH, 2-Me-3-OH, 4-Me-3-OH; R1 = Ph, 4-OMe, pyridin-2-yl, etc.] via chemoselective N-arylation of 3-aminophenols and aryl iodides using 1,3-bis-[2-hydroxyphenyl] imidazolium chloride (IHPHCl) and copper iodide as catalyst (1 mol %) in aqueous medium. Presence of chelating group (-OH) on IHPHCl enhanced N-selectivity. Overall this was a simple and green method for selective N-arylation of 3-aminophenols with good substrate scope and yields (60-88%).
Name: 3-Iodopyridine, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.
3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.
3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com