Iodides-buliding-blocks

A new type of self-supported, polymeric Ru-carbene complex for homogeneous catalysis and heterogeneous recovery: synthesis and catalytic activities for ring-closing metathesis was written by Chen, Shu-Wei;Kim, Ju Hyun;Shin, Hyunik;Lee, Sang-gi. And the article was included in Organic & Biomolecular Chemistry in 2008.Related Products of 10297-05-9 This article mentions the following:

A novel second generation Grubbs-type catalyst tethered to isopropoxystyrene has been synthesized and automatically polymerized in solution to form a self-supported polymeric Ru-carbene complex, which catalyzed ring-closing metathesis homogeneously, but was recovered heterogeneously. In the experiment, the researchers used many compounds, for example, 1-Chloro-4-iodobutane (cas: 10297-05-9Related Products of 10297-05-9).

1-Chloro-4-iodobutane (cas: 10297-05-9) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. The C–I bond is the weakest of the carbon–halogen bonds. These bond strengths correlate with the electronegativity of the halogen, decreasing in the order F > Cl > Br > I.Related Products of 10297-05-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Oxidation of Iodo- and Bromo-Substituted Polymethylbenzenes in the System PbO₂-CF₃COOH-CH₂Cl₂ was written by Sandzhieva, M. A.;Aryamova, E. S.;Sukharzhevskii, S. M.;Grinenko, E. V.;Vasilyev, A. V.. And the article was included in Russian Journal of Organic Chemistry in 2018.Formula: C10H12I2 This article mentions the following:

The oxidation of mono- and diiodo- and -bromo-substituted polymethylbenzenes (mesitylene and durene) in the system PbO₂-CF₃COOH-CH₂Cl₂ at room temperature (2-70 h) leads mainly to the formation of iodo- and bromobenzyl alcs. as result of oxidation of Me group. The reaction involves intermediate formation of haloarene radical cations. ESR study of these radical cations made it possible to determine the structure of their singly occupied MOs a₂ or b₁ and interpret their reactivity. In the experiment, the researchers used many compounds, for example, 1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1Formula: C10H12I2).

1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Formula: C10H12I2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

A Practical Way to Prepare Isobutyronitrile Amides through Reactions between Carboxylic Acids and Azobisisobutyronitrile was written by Rong, Guangwei;Liu, Defu;Yan, Hong;Chen, Jie;Zheng, Yang;Zhang, Guoqi;Mao, Jincheng. And the article was included in Advanced Synthesis & Catalysis in 2015.SDS of cas: 13420-63-8 This article mentions the following:

A practical and efficient synthesis of N-isobutyronitrile amides R¹C(O)N(R²)C(CN)(R³)R⁴ (R¹ = 2-BrC₆H₄, 4-H₃CC₆H₄CH:CH, furan-2-yl, naphthalen-1-yl, etc.; R² = H, C(O)CH(CH₃)₂, C(O)C₆H₅, C(O)CH(CH₃)CH₂CH₃; R³ = R⁴ = Me, Et) has been achieved through the direct condensation of carboxylic acids bearing variously substituted Ph rings/cinnamic acid/phenylpropiolic acid and azobisisobutyronitrile (AIBN). A radical pathway was proposed and the methodol. requires no catalysts and additives, and represents the first practical approach to a variety of valuable amides containing the isobutyronitrile structural unit. In the experiment, the researchers used many compounds, for example, 2-Chloro-6-iodobenzoic acid (cas: 13420-63-8SDS of cas: 13420-63-8).

2-Chloro-6-iodobenzoic acid (cas: 13420-63-8) belongs to iodide derivatives. Organoiodine compounds occur widely in organic chemistry, but are relatively rare in nature. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.SDS of cas: 13420-63-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Mild and Copper-Free Stereoselective Cyanation of gem-Difluoroalkenes by Using Benzyl Nitrile as a Cyanating Reagent was written by Zhang, Juan;Xu, Chengyuan;Wu, Wei;Cao, Song. And the article was included in Chemistry – A European Journal in 2016.Application In Synthesis of 4-Iodo-1,2-dimethoxybenzene This article mentions the following:

A novel copper-free highly stereoselective cyanation of gem-difluoroalkenes by using benzyl nitrile as a cyanating reagent with the assistance of tBuOLi under air atm. at room temperature was developed. A variety of versatile fluorinated alkenyl nitriles I (Ar = 4-CH₃OC₆H₄, 4-(CH₃)₂NC₆H₄, 4-CH₃C₆H₄, 3-ClC₆H₄, etc.) were obtained. The proposed mechanism involved the C-H bond oxidation, C-CN bond cleavage, and then nucleophilic vinylic substitution (SNV). In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Application In Synthesis of 4-Iodo-1,2-dimethoxybenzene).

4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Application In Synthesis of 4-Iodo-1,2-dimethoxybenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The First Modular Route to Core-Chiral Bispidine Ligands and Their Application in Enantioselective Copper(II)-Catalyzed Henry Reactions was written by Scharnagel, Dagmar;Mueller, Andreas;Prause, Felix;Eck, Martin;Goller, Jessica;Milius, Wolfgang;Breuning, Matthias. And the article was included in Chemistry – A European Journal in 2015.Category: iodides-buliding-blocks This article mentions the following:

The first modular and flexible synthesis of core-chiral bispidines e.g. I was achieved by using an “inside-out” strategy. The key intermediate, a NBoc-activated bispidine lactam, was constructed in enantiomerically pure form from a chirally modified -amino acid and 2-(acetoxymethyl)acrylonitrile in just five steps and good 48 % yield. A simple addition-reduction protocol permitted a highly endo-selective introduction of substituents and, thus, a fast and variable access to 2-endo-substituted and 2-endo,N-fused bi- and tricyclic bispidines. The new diamines were evaluated as the chiral ligands in asym. Henry reactions. Excellent enantioselectivities of up to 99 % ee and good diastereomeric ratios of up to 86:14 were reached with a copper(II) complex modified by a 2-endo,N-(3,3-dimethylpyrrolidine)-annelated bispidine. Its performance is superior to that of the well-known bispidines (-)-sparteine and the (+)-sparteine surrogate. In the experiment, the researchers used many compounds, for example, 1-Chloro-4-iodobutane (cas: 10297-05-9Category: iodides-buliding-blocks).

1-Chloro-4-iodobutane (cas: 10297-05-9) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Regioselective formation of imidazol-2-yllithium, imidazol-4-yllithium, and imidazol-5-yllithium species was written by Groziak, Michael P.;Wei, Lulin. And the article was included in Journal of Organic Chemistry in 1991.Synthetic Route of C3H2I2N2 This article mentions the following:

Representative imidazol-2-yllithium, imidazol-4-yllithium, and imidazol-5-yllithium species have been prepared via halogen-metal exchange, and the propensity of the latter two to undergo isomerization and quench by electrophilic reagents has been studied. The C2-substituted imidazol-5-yllithium species (I) is generated within 10 min at -78° from 1-[(benzyloxy)methyl]-4,5-diiodoimidazole and affords the C5-formyl product II upon reaction with DMF, but gives the isomeric C2-formyl product III if allowed to equilibrate to the imidazol-2-yllithium species IV for an addnl. 35 min at -78° before quench. The less reactive electrophile di-Et carbonate is unable to trap I and instead reacts with IV to afford tris[1-[(benzyloxy)methyl]-4-iodo-2-imidazolyl]carbinol. In contrast, 1-[(benzyloxy)methyl]-4-iodoimidazole-5-carboxaldehyde ethylene acetal metalates to give the C2-unsubstituted imidazol-4-yllithium species, which undergoes a very rapid conversion to its imidazol-2-yllithium isomer, even at -100°, giving the 2,5-dicarboxaldehyde-5-ethylene acetal or the 2-deuterio 5-carboxaldehyde ethylene acetal V upon quench with DMF or D₂O, resp. Thus, in the presence of C2 unsubstitution , C5 functionalization could be accomplished when the electrophile was sufficiently reactive, while C4 functionalization could not. Short- and long-range ¹H-¹³C heteronuclear (Hetcor) 2D NMR spectroscopic analyses were instrumental in the structural assignments of key compounds In the experiment, the researchers used many compounds, for example, 4,5-Diiodo-1H-imidazole (cas: 15813-09-9Synthetic Route of C3H2I2N2).

4,5-Diiodo-1H-imidazole (cas: 15813-09-9) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Synthetic Route of C3H2I2N2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Lewis Acid Catalyzed Tandem Polycyclization of Internal Alkynols and Vinyl Azides was written by Siyang, Hai Xiao;Ji, Xiao Yue;Wu, Xu Rui;Wu, Xin Yan;Liu, Pei Nian. And the article was included in Organic Letters in 2015.Related Products of 877264-43-2 This article mentions the following:

A novel Lewis acid catalyzed tandem cyclization reaction of internal alkynols and vinyl azides has been achieved to afford a series of products containing a pyran-based indeno[1,2-c]isochromene scaffold e. g., I, in moderate to high yields. This tandem polycyclization protocol provides a straightforward entry to construct the complex polycyclic skeleton through cycloisomerization, formal [4 + 2] cycloaddition, and an elimination process. In the experiment, the researchers used many compounds, for example, (5-Fluoro-2-iodophenyl)methanol (cas: 877264-43-2Related Products of 877264-43-2).

(5-Fluoro-2-iodophenyl)methanol (cas: 877264-43-2) belongs to iodide derivatives. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Related Products of 877264-43-2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Quantitative estimation of steric effects. III. Substituent constants and steric contributions to chemical shifts of methyl group protons in ring iodinated methylbenzenes was written by Lindberg, James G.;Leong, Ambrose. And the article was included in Journal of Magnetic Resonance (1969-1992) in 1975.Related Products of 3268-21-1 This article mentions the following:

PMR spectra were systematically analyzed for 27 methylbenzenes and corresponding ring iodinated derivatives based on toluene, o-, m-, and p-xylenes, mesitylene, durene, pentamethylbenzene, and hexamethylbenzene. Typical changes in the chemical shift of methyl group protons attributable to the presence of ortho, meta, and para iodine atoms and methyl groups were calculated. Unusually large low field shifts occurred in sterically crowded molecules. In ring periodinated compounds, PMR signals of methyl group protons occurred at lower fields up to 0.94 ppm relative to a predicted position, one of the largest steric shifts yet reported. A table is presented summarizing the generally useful substituent constant data obtained from examination of 59 methylbenzenes and ring halogenated derivatives In the experiment, the researchers used many compounds, for example, 1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1Related Products of 3268-21-1).

1,4-Diiodo-2,3,5,6-tetramethylbenzene (cas: 3268-21-1) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Organoiodine lubricants can be used with titanium, stainless steels, and other metals which tend to seize up with conventional lubricants: organoiodine lubricants can be used in turbines and spacecraft, and as a cutting oil in machining.Related Products of 3268-21-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

A practical and scalable system for heteroaryl amino acid synthesis was written by Aycock, R. A.;Vogt, D. B.;Jui, N. T.. And the article was included in Chemical Science in 2017.Product Details of 153034-88-9 This article mentions the following:

A robust system for the preparation of β-heteroaryl α-amino acid derivatives has been developed using photoredox catalysis. This system operates via regiospecific activation of halogenated pyridines (or other heterocycles) and conjugate addition to dehydroalanine derivatives to deliver a wide range of unnatural amino acids. This process was conducted with good efficiency on large scale, the application of these conditions to amino ketone synthesis is shown, and a simple protocol is given for the preparation of enantioenriched amino acid synthesis, from a number of radical precursors. In the experiment, the researchers used many compounds, for example, 2-Chloro-4-iodo-3-methylpyridine (cas: 153034-88-9Product Details of 153034-88-9).

2-Chloro-4-iodo-3-methylpyridine (cas: 153034-88-9) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. A typical method for synthesis of aromatic iodides is diazotization of primary aromatic amines followed by treatment of potassium iodide. Aliphatic alcohols are converted to alkyl iodides by treating with hydrogen iodide.Product Details of 153034-88-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Enhancing charge mobilities in selectively fluorinated oligophenyl organic semiconductors: a design approach based on experimental and computational perspectives was written by Maiti, Buddhadev;Wang, Kunlun;Bhandari, Srijana;Bunge, Scott D.;Twieg, Robert J.;Dunietz, Barry D.. And the article was included in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices in 2019.Recommanded Product: 64248-57-3 This article mentions the following:

Fluorination can be used to tune optoelectronic properties at the mol. level. A series of oligophenyls with various difluorinations of the Ph rings has been synthesized, crystalized, structurally resolved and computationally analyzed for charge mobility. We find that difluorination of the Ph rings at para positions leads to oligophenyls that are stacked in sym. overlap with significantly enhanced hole mobility as well as the highest electron mobility of the mols. considered. Other difluorinations lead to relatively shifted mol. units in the π-stacked crystal and therefore to lower mobilities. The selectively fluorinated oligophenyls were synthesized using the Suzuki-Miyaura cross coupling reaction. The structures of the products were characterized by X-ray diffraction (XRD), ¹H, ¹³C, ¹⁹F NMR spectroscopy and gas chromatog. (GC)/mass spectroscopy (MS) measurements. Computational anal. of the materials based on state-of-the-art tools are used to predict their charge transport properties in the crystal phase. In short, we establish a mol. design approach based on fluorination of oligophenyls to achieve enhanced hole mobilities and relatively high electron mobilities. In the experiment, the researchers used many compounds, for example, 1,2-Difluoro-3-iodobenzene (cas: 64248-57-3Recommanded Product: 64248-57-3).

1,2-Difluoro-3-iodobenzene (cas: 64248-57-3) belongs to iodide derivatives. Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Polyiodoorganic compounds are sometimes employed as X-ray contrast agents, in fluoroscopy, a type of medical imaging. This application exploits the X-ray absorbing ability of the heavy iodine nucleus.Recommanded Product: 64248-57-3

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com