Tag: 200-300

Rerkrachaneekorn, Tanawat; Tankam, Theeranon; Sukwattanasinitt, Mongkol; Wacharasindhu, Sumrit published their research in Tetrahedron Letters in 2021. The article was titled 《NaI-mediated oxidative amidation of benzyl alcohols/aromatic aldehydes to benzamides via electrochemical reaction》.Related Products of 15164-44-0 The article contains the following contents:

In this research, authors have developed a mild electrochem. process for oxidative amidation of benzyl alcs./aromatic aldehydes with cyclic amines into the corresponding benzamides. This electroorg. synthetic method proceeds using NaI as a redox mediator under ambient temperature in undivided cell, providing more than 25 examples of amide products in moderate to good yields. The benefits of this reaction include one-pot synthesis, open air condition, proceed in aqueous media and no requirement of external conducting salt, base and oxidant. In the experiment, the researchers used many compounds, for example, 4-Iodobenzaldehyde(cas: 15164-44-0Related Products of 15164-44-0)

4-Iodobenzaldehyde(cas: 15164-44-0) is used in synthesis of 4-[2-(trimethylsilyl)ethynyl]benzaldehyde, 5,15-dimesityl-10-(3-[2-(trimethylsilyl)ethynyi]phenyl}-20-(4-iodophenyl)porphyrin, and 5,15-dimesityl-10-[3,5-bis{2-[4-(N,N’-difluoroboryl-1,9-dimethyidipyrrin-5-yl)-phenyl]ethynyl}phenyl]-20-(4-iodophenyl)porphyrin.Related Products of 15164-44-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Double carbonylation of iodoarenes in the presence of a pyridinium SILP-Pd catalyst》 was written by Urban, Bela; Nagy, Eniko; Nagy, Petra; Papp, Mate; Skoda-Foldes, Rita. Recommanded Product: 591-18-4 And the article was included in Journal of Organometallic Chemistry in 2020. The article conveys some information:

The efficiency of a palladium catalyst, immobilized on a supported ionic liquid phase (SILP) with adsorbed 1-butyl-4-methylpyridinium chloride, was investigated in aminocarbonylation reactions. Double carbonylation was found to be the main reaction using different iodoarenes and aliphatic amines as substrates. Application of aniline derivatives as nucleophiles led to the exclusive formation of substituted benzamides. The stabilization effect of the adsorbed pyridinium ionic liquid was compared to that of imidazolium and phosphonium derivatives It was proved that the pyridinium SILP-palladium catalyst could be reused in at least 10 cycles. Recyclability was tested in five successive runs for all of the substrates. The results came from multiple reactions, including the reaction of 1-Bromo-3-iodobenzene(cas: 591-18-4Recommanded Product: 591-18-4)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Recommanded Product: 591-18-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Mechanochromic Luminescence from Crystals Consisting of Intermolecular Hydrogen-Bonded Sheets》 was written by Sagara, Yoshimitsu; Takahashi, Kiyonori; Nakamura, Takayoshi; Tamaoki, Nobuyuki. HPLC of Formula: 626-02-8 And the article was included in Chemistry – An Asian Journal in 2020. The article conveys some information:

Introduction of functional groups that can form intermol. hydrogen bonds into highly-emissive luminophores is a promising way to induce mechanochromic luminescence. Herein, we report that a 9,10-bis(phenylethynyl)anthracene derivative featuring two amide groups forms green-emissive crystals based on two-dimensional hydrogen-bonded mol. sheets. Mech. grinding changed the emission from green to yellow, owing to a transition from a crystalline to an amorphous phase. IR spectroscopy revealed that mech. stimuli disrupted the linear hydrogen-bonding formation. A thermal treatment recovered the original green photoluminescence. In the experimental materials used by the author, we found 3-Iodophenol(cas: 626-02-8HPLC of Formula: 626-02-8)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.HPLC of Formula: 626-02-8

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Ruthenium(II)-Catalyzed Homocoupling of Weakly Coordinating Sulfoxonium Ylides via C-H Activation/Annulations: Synthesis of Functionalized Isocoumarins》 were Zhou, Ming-Dong; Peng, Zhen; Wang, He; Wang, Zhao-Hui; Hao, Da-Jin; Li, Lei. And the article was published in Advanced Synthesis & Catalysis in 2019. Product Details of 1774-47-6 The author mentioned the following in the article:

Homocoupling of weakly coordinating sulfoxonium ylides was accomplished via a ruthenium(II) catalyzed C-H activation process. This strategy provides a convenient, efficient and step-economic method to access 3-substituted isocoumarins with good functional group tolerance. The sulfoxonium ylide acts both as the convenient aromatic substrate and the acylmethylation reagent in this transformation. Moreover, the products could be transformed into diverse valuable derivatives In the part of experimental materials, we found many familiar compounds, such as Trimethylsulfoxonium iodide(cas: 1774-47-6Product Details of 1774-47-6)

Trimethylsulfoxonium iodide(cas: 1774-47-6) reacts with sodium hydride to prepare dimethyloxosulfonium methylide, which is used as a methylene-transfer reagent in synthetic chemistry. It is used to prepare ylide, which reacts with carbonyl compounds to get epoxides. Further, it reacts with alfa,beta-unsaturated esters to get cyclopropyl esters.Product Details of 1774-47-6

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2018,Wangoli, Panyako Asman; Kinunda, Grace published 《The effect of alkyl chain tethers on the kinetics and mechanistic behaviour of bifunctional dinuclear platinum(II) complexes bearing N,N’-dipyridylamine ligands》.New Journal of Chemistry published the findings.Reference of 1,2-Diiodoethane The information in the text is summarized as follows:

In the current paper, the authors report the kinetics of bifunctional dinuclear Pt(II) complexes, viz., {1,2-bis(di-2-pyridylamino)alkane}tetraaquadiplatinum(II), alkane = (CH2)2 (PtL2), (CH2)3 (PtL3), (CH2)4 (PtL4), (CH2)5 (PtL5) and (CH2)6 (PtL6). The substitution reactions were carried out on tetraaqua complexes with thiourea nucleophiles under pseudo-first-order conditions as a function of nucleophile concentration and temperature by stopped-flow and UV-visible spectrophotometric techniques. An exptl. study was conducted with the aim of determining the influence of alkyl chains on the steric and electronic structure of dinuclear Pt(II) complexes. The reactivity of these complexes was dependent on the length of the alkylene spacer. The results obtained herein demonstrate the intriguing odd-even effects induced by the alkyl chain on the complexes. Artificial constraints imposed by the alkyl chain significantly affect their conformational structure to be either synperiplanar (syn-) or antiperiplanar (anti-) characterized by the odd and even effect. The kinetic, mechanistic and conformational behavior was influenced by the size of the alkyl chain in accordance with odd-even alterations of the spacer. Computational modeling using d. functional theory (DFT) calculations supplemented exptl. findings that structural features and the reactivity pattern of these metal complexes are governed by both steric and electronic effects arising from the flexibility and inductive nature of the alkyl spacer. The strong σ-donicity of longer alkyl chains favors sufficient accumulation of electron d. at the metal center and stabilizes a 14-electron intermediate. The study shows the HOMO-LUMO energy (ΔE) is affected by the length of the spacer. Kinetic and DFT data indicate electron donation by the alkyl spacer. The low pos. values of enthalpy of activation and significantly large neg. values of entropy of activation indicate an associative mechanism of substitution. The experimental part of the paper was very detailed, including the reaction process of 1,2-Diiodoethane(cas: 624-73-7Reference of 1,2-Diiodoethane)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Reference of 1,2-Diiodoethane

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2016,Toontom, N.; Posri, W.; Lertsiri, S.; Meenune, M. published 《Effect of drying methods on Thai dried chilli’s hotness and pungent odour characteristics and consumer liking》.International Food Research Journal published the findings.Formula: C2H4I2 The information in the text is summarized as follows:

Dried chilli is widely used for its hotness and pungent odor enhancing properties. In an attempt to get a broad overview of drying effects on hotness and pungent odor characteristics contributing to dominant features of various types of Thai dried chilli, major volatile flavor compounds responsible for perceived hotness and pungent odor of the dried chilli-(freeze (FD), hot air (HD) and sun (SD) dried samples) were identified by trained panel (n = 15) in conjunction with HS-SPME/GC-MS and LLE/GC-MS. Consumer liking of the three dried chilli was assessed on the basis of pungent odor and hotness characteristics by Thai consumers (n = 120) using 9 point-category hedonic scale. The GC-MS and trained panel data were analyzed by PLS and results show that capsaicin was the main compound responsible for the oral hotness sensation, while 1-penten-3-one compound was found to be an indicator of strong pungent odor. The FD sample presented the highest intensity of hotness characteristic (p≤0.05). The content of 1-penten-3-one in FD was also higher than that of HD and SD. Although trained panellists could not differentiate between the intensities of pungent odor of FD and HD (p>0.05), consumers had a tendency to prefer HD. This research proposes that there is substantial value to anal. such as this that integrates human sensorial perception with objective measurement. The outputs of this research can be used to provide guidance on dried chilli product development based on consumer acceptance criteria. The experimental part of the paper was very detailed, including the reaction process of 1,2-Diiodoethane(cas: 624-73-7Formula: C2H4I2)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Formula: C2H4I2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Korsager, Signe; Taaning, Rolf H.; Lindhardt, Anders T.; Skrydstrup, Troels published an article in Journal of Organic Chemistry. The title of the article was 《Reductive Carbonylation of Aryl Halides Employing a Two-Chamber Reactor: A Protocol for the Synthesis of Aryl Aldehydes Including 13C- and D-Isotope Labeling》.Safety of N-(4-Iodophenyl)cyclopropanecarboxamide The author mentioned the following in the article:

A protocol has been developed for conducting the palladium-catalyzed reductive carbonylation of aryl iodides and bromides using 9-methylfluorene-9-carbonyl chloride (COgen) as a source of externally delivered carbon monoxide in a sealed two-chamber system (COware), and potassium formate as the in situ hydride source. The method is tolerant to a wide number of functional groups positioned on the aromatic ring, and it can be exploited for the isotope labeling of the aldehyde group. Hence, reductive carbonylations run with 13COgen provide a facile access to 13C-labeled aromatic aldehydes, whereas with DCO2K, the aldehyde is specifically labeled with deuterium. Two examples of double isotopic labeling are also demonstrated. Finally, the method was applied to the specific carbon-13 labeling of the β-amyloid binding compound, florbetaben. After reading the article, we found that the author used N-(4-Iodophenyl)cyclopropanecarboxamide(cas: 23779-17-1Safety of N-(4-Iodophenyl)cyclopropanecarboxamide)

N-(4-Iodophenyl)cyclopropanecarboxamide(cas: 23779-17-1) belongs to anime. Amines characteristically form salts with acids; a hydrogen ion, H+, adds to the nitrogen. With the strong mineral acids (e.g., H2SO4, HNO3, and HCl), the reaction is vigorous. Salt formation is instantly reversed by strong bases such as NaOH. Neutral electrophiles (compounds attracted to regions of negative charge) also react with amines; alkyl halides (R′X) and analogous alkylating agents are important examples of electrophilic reagents.Safety of N-(4-Iodophenyl)cyclopropanecarboxamide

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2016,Nakayama, Yasuaki; Maeda, Yuichiro; Kotatsu, Masayuki; Sekiya, Ruriko; Ichiki, Masato; Sato, Takaaki; Chida, Noritaka published 《Enantioselective Total Synthesis of (+)-Neostenine》.Chemistry – A European Journal published the findings.Formula: C2H4I2 The information in the text is summarized as follows:

A chirality transfer approach using acyclic polyol intermediates for the synthesis of (+)-neostenine (1, I) has been developed. The sequential Overman/Claisen rearrangement of an allylic 1,2-diol was especially useful, installing two contiguous stereocenters with complete diastereoselectivity in a one-pot sequence. The SmI2-mediated cyclization and the subsequent chemoselective reduction of a lactam moiety accomplished the first enantioselective total synthesis of (+)-neostenine (1). In the experimental materials used by the author, we found 1,2-Diiodoethane(cas: 624-73-7Formula: C2H4I2)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Formula: C2H4I2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Synthesis of trifluoromethylthiolated pyridinones through the copper-mediated trifluoromethylthiolation of iodopyridinones》 were Luo, Beibei; Zhang, Yunxiao; You, Yi; Weng, Zhiqiang. And the article was published in Organic & Biomolecular Chemistry in 2016. Synthetic Route of C6H6INO The author mentioned the following in the article:

An operationally simple method for the copper-mediated trifluoromethylthiolation of iodopyridinones employing (bpy)CuSCF3 (bpy = 2,2′-bipyridine) as a trifluoromethylthiolating reagent was presented. Various types of iodopyridinones were applicable and the trifluoromethylthiolated pyridinones were obtained in moderate to excellent yields. This method tolerated a variety of protecting groups on the nitrogen atom of pyridinones. In addition, scalability of the reaction was demonstrated. The results came from multiple reactions, including the reaction of 4-Iodo-1-methylpyridin-2(1H)-one(cas: 889865-47-8Synthetic Route of C6H6INO)

4-Iodo-1-methylpyridin-2(1H)-one(cas: 889865-47-8) belongs to organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs.Synthetic Route of C6H6INO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Liu, Jing-Bo; Li, Feng-Yun; Dong, Jing-Yue; Li, Yu-Xin; Zhang, Xiu-Lan; Wang, Yuan-Hong; Xiong, Li-Xia; Li, Zheng-Ming published an article in Bioorganic & Medicinal Chemistry. The title of the article was 《Anthranilic diamides derivatives as potential ryanodine receptor modulators: Synthesis, biological evaluation and structure activity relationship》.Recommanded Product: 1-Chloro-4-iodo-2-nitrobenzene The author mentioned the following in the article:

A series of novel anthranilic diamides derivatives (7a-s) containing halogen, trifluoromethyl group and cyano group were designed, synthesized, and characterized by m.p., 1H NMR, 13C NMR and elemental analyses. The bioactivity revealed that most of them showed moderate to excellent activities against oriental armyworm (Mythimna separata) and diamondback moth (Plutella xylostella). Above all, the larvicidal activity of I against oriental armyworm was 100% and 40% at 0.25 and 0.1 mg L-1, comparable to that of the standard chlorantraniliprole (100%, 0.25 mg L-1 and 20%, 0.1 mg L-1). What is more, 7o against diamondback moth displayed 90% insecticidal activity at 0.01 mg L-1, superior to chlorantraniliprole (45%, 0.01 mg L-1). The experiments I on the American cockroach (Periplaneta Americana) heart beating rates (Dorsal vessel) and contractile force were compared with chlorantraniliprole. In addition, I could affect the calcium homeostasis in the central neurons of the third larvae of oriental armyworm, which revealed that the ryanodine receptor is the potential target of I. The d. functional theory (DFT) calculation results revealed the amide bridge, the benzene ring of anthraniloyl moiety and pyrazole ring might play an important role in the insecticidal activity through hydrophobic interactions and π-π conjugations. In the experimental materials used by the author, we found 1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3Recommanded Product: 1-Chloro-4-iodo-2-nitrobenzene)

1-Chloro-4-iodo-2-nitrobenzene(cas: 41252-95-3) belongs to organic iodides.Recommanded Product: 1-Chloro-4-iodo-2-nitrobenzene The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com