Tag: M.W=100-200

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Dalton Transactions called Lithium heterocuprates: the influence of the amido group on organoamidocuprate structures, Author is Bomparola, Roberta; Davies, Robert P.; Hornaeur, Stefan; White, Andrew J. P., which mentions a compound: 75732-01-3, SMILESS is [Cu]C1=C(C)C=C(C)C=C1C, Molecular C9H11Cu, HPLC of Formula: 75732-01-3.

Li organoamidocuprates LiCuR(NR’2) are an important class of organocopper reagents and found widespread application in conjugate addition and other bond-forming reactions. The dependence of the structures and equilibrium of these species on the steric and electronic properties of the amido group is reported in both the solid state and in solution Three different cuprate complexes were crystallog. characterized: the organoamidocuprate [Cu2Li2Mes2TMP2] (2) (TMP = 2,2,6,6-tetramethylpiperidide) which is shown to adopt a head-to-tail conformation; [Cu2Li2(N(CH2Ph)CH2CH2NMe2)4] (3) which is a homoamidocuprate and contains addnl. coordination of the Li centers from intra-mol. tertiary amine groups; and the diastereomeric organoamidocuprate [Cu2Li2Mes2(N(R-CH(Ph)Me)(CH2CF3))2] (4) which adopts a head-to-head conformation. Complex 4 is unique in being the 1st crystallog. characterized example of a head-to-head isomer of a heterocuprate, and its structure also has implications for the use of scalemic amidocuprates in asym. induced conjugate addition The solution equilibrium of all new complexes also were studied using 7Li NMR spectroscopy, and in each case the species observed in the crystal structure was shown to also be the predominant isomer in solution

Here is just a brief introduction to this compound(75732-01-3)HPLC of Formula: 75732-01-3, more information about the compound(Mesitylcopper(I)) is in the article, you can click the link below.

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Lithium heterocuprates: the influence of the amido group on organoamidocuprate structures》. Authors are Bomparola, Roberta; Davies, Robert P.; Hornaeur, Stefan; White, Andrew J. P..The article about the compound:Mesitylcopper(I)cas:75732-01-3,SMILESS:[Cu]C1=C(C)C=C(C)C=C1C).HPLC of Formula: 75732-01-3. Through the article, more information about this compound (cas:75732-01-3) is conveyed.

Li organoamidocuprates LiCuR(NR’2) are an important class of organocopper reagents and found widespread application in conjugate addition and other bond-forming reactions. The dependence of the structures and equilibrium of these species on the steric and electronic properties of the amido group is reported in both the solid state and in solution Three different cuprate complexes were crystallog. characterized: the organoamidocuprate [Cu2Li2Mes2TMP2] (2) (TMP = 2,2,6,6-tetramethylpiperidide) which is shown to adopt a head-to-tail conformation; [Cu2Li2(N(CH2Ph)CH2CH2NMe2)4] (3) which is a homoamidocuprate and contains addnl. coordination of the Li centers from intra-mol. tertiary amine groups; and the diastereomeric organoamidocuprate [Cu2Li2Mes2(N(R-CH(Ph)Me)(CH2CF3))2] (4) which adopts a head-to-head conformation. Complex 4 is unique in being the 1st crystallog. characterized example of a head-to-head isomer of a heterocuprate, and its structure also has implications for the use of scalemic amidocuprates in asym. induced conjugate addition The solution equilibrium of all new complexes also were studied using 7Li NMR spectroscopy, and in each case the species observed in the crystal structure was shown to also be the predominant isomer in solution

Here is just a brief introduction to this compound(75732-01-3)HPLC of Formula: 75732-01-3, more information about the compound(Mesitylcopper(I)) is in the article, you can click the link below.

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: 2-Methylglutaronitrile, is researched, Molecular C6H8N2, CAS is 4553-62-2, about Microbial degradation of nitrile compounds. Part III. Degradation of dinitriles by Fusarium merismoides TG-1, the main research direction is dinitrile metabolism Fusarium.Quality Control of 2-Methylglutaronitrile.

The triacrylonitrile-utilizing fungus F. merismoides TG-1 grew on a medium containing dinitriles as the N source. It degraded glutaronitrile to 4-cyanobutyric acid and diacrylonitrile to 4-cyanopentanoic acid.

Here is just a brief introduction to this compound(4553-62-2)Quality Control of 2-Methylglutaronitrile, more information about the compound(2-Methylglutaronitrile) is in the article, you can click the link below.

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 2-Methylglutaronitrile(SMILESS: N#CC(C)CCC#N,cas:4553-62-2) is researched.Synthetic Route of C34H18F16IrN4P. The article 《Influence of the medium on hydrogenation of 2-methylglutaronitrile. Selective access to 2-methylpentane diamine or β-picoline after dehydrogenation》 in relation to this compound, is published in Chemical Industries (Dekker). Let’s take a look at the latest research on this compound (cas:4553-62-2).

A conference. The 2-methylglutaronitrile (I) is obtained as a byproduct of the important adiponitrile production It, nevertheless, gives rise to interesting chem. transformations. In particular, its hydrogenation can produce 2-methylpentanediamine, a substitute for hexamethylenediamine in polyamide or polyurethane compounds The 3-methylpiperidine, also produced by hydrogenation of I, can be an interesting intermediate for β-picoline production involved in the synthesis of PP vitamin. Using Raney nickel as the catalyst, hydrogenation reactions were performed in various liquid phase compositions 2-Methylpentanediamine was obtained very selectively. The reaction product can be used itself as solvent. Addition of dry ammonia in ethanol in the place of isopropanol / KOH or NaOH medium leads to a mixture of 2-methylpentanediamine, 3-methylpiperidine and some heavy byproducts. This mixture can be cyclized and dehydrogenated to β-picoline (3-methylpyridine) on a special and very efficient Pd/SiO2 catalyst. The two processes have been patented by Rhone-Poulenc.

Here is just a brief introduction to this compound(4553-62-2)HPLC of Formula: 4553-62-2, more information about the compound(2-Methylglutaronitrile) is in the article, you can click the link below.

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Computed Properties of C3H7ClO2. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: (2S)-(+)-3-Chloropropane-1,2-diol, is researched, Molecular C3H7ClO2, CAS is 60827-45-4, about Three different types of chirality-driven crystallization within the series of uniformly substituted phenyl glycerol ethers. Author is Bredikhin, Alexander A.; Bredikhina, Zemfira A.; Novikova, Victorina G.; Pashagin, Alexander V.; Zakharychev, Dmitry V.; Gubaidullin, Aidar T..

Seven chiral aryl glycerol ethers 2-R-C6H4-O-CH2CH(OH)CH2OH (R = H, Me, Et, Allyl, n-Pr, i-Pr, tert-Bu) were synthesized in racemic and scalemic form. The IR spectra, m.ps., and enthalpies of fusion for racemic and scalemic samples of every species were measured, the entropies of enantiomers mixing in the liquid state and Gibbs free energies of a racemic compound formation were derived and binary phase diagrams were reconstructed for the whole family. Solid racemic compounds stabilities were ranked for the four substances. Spontaneous resolution was established for the registered chiral drug mephenesin and its Et analog. Metastable anomalous conglomerate, forming crystals having three independent R* and one independent S* mols. in the unit cell, is formed during solution crystallization of tert-Bu derivative; metastable phase transforms slowly into traditional racemic conglomerate.

Here is just a brief introduction to this compound(60827-45-4)Computed Properties of C3H7ClO2, more information about the compound((2S)-(+)-3-Chloropropane-1,2-diol) is in the article, you can click the link below.

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Journal of Coordination Chemistry called Unusual structurally characterized pyridine carbinoxide copper(II) coordination compounds, isolated from organic solvents, Author is Boyle, Timothy J.; Ottley, Leighanna M.; Raymond, Rebecca, which mentions a compound: 75732-01-3, SMILESS is [Cu]C1=C(C)C=C(C)C=C1C, Molecular C9H11Cu, Computed Properties of C9H11Cu.

The coordination behavior of pyridine-2-methanol (H-OPy) with copper in organic solvents was crystallog. determined Initial attempts to generate the Cu(II) OPy derivatives from an alcoholysis exchange of Cu(OCH3)2, with H-OPy in toluene, gave [Cu(μc-OPy)(OcPy)]2 (1, c indicates chelation). The square-based pyramidal geometries noted for each Cu center resulted from one OcPy and two μc-OPy ligands, generating an unusual Ci symmetry. From the reaction of H-OPy and the Cu(I) species Cu(C6H2(CH3)3-2,4,6), mononuclear Cu(II) complex Cu(OcPy)2(H-OPy)2 (2) was isolated. Compound 2 is unusual in that it adopts a square planar arrangement around the Cu metal center using two OcPy ligands; however, the metal center also coordinates with two H-OPy mols. forming an octahedral geometry. Upon dissolution in water, both 1 and 2 react to form the previously reported Cu(OcPy)2·2H2O (3). Attempts to add a Lewis base through dissolution of 1 in selected solvents (i.e., THF, pyridine, 1-methylimidazole) led to [Cu(μc-OPy)(OcPy)]2·H2O (4), which possesses a C2 symmetry. The water was believed to be extracted from the dry solvents. A Cl derivative was also solved for the Cu(II)/Cu(I) species [Cu(OPy)2]2[CuCl(H-OPy)2]2 (5) from THF dried over apparently contaminated sieves. 1-5 Were characterized by x-ray crystallog.

Here is just a brief introduction to this compound(75732-01-3)Computed Properties of C9H11Cu, more information about the compound(Mesitylcopper(I)) is in the article, you can click the link below.

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 75732-01-3, is researched, SMILESS is [Cu]C1=C(C)C=C(C)C=C1C, Molecular C9H11CuJournal, Tetrahedron called A simplified catalytic system for direct catalytic asymmetric aldol reaction of thioamides; application to an enantioselective synthesis of atorvastatin, Author is Kawato, Yuji; Iwata, Mitsutaka; Yazaki, Ryo; Kumagai, Naoya; Shibasaki, Masakatsu, the main research direction is atorvastatin enantioselective synthesis; ketoester preparation amination cyclization; hydroxyalkyl thioamide preparation lithium reagent; thioamide aldehyde aldol reaction Cu catalyst.Reference of Mesitylcopper(I).

A new catalytic system was developed for the direct catalytic asym. aldol reaction of thioamides. The new lithium-free Cu catalyst (second-generation catalyst) exhibited enhanced catalytic efficiency over the previously developed catalyst comprising [Cu(CH3CN)4]PF6/Ph-BPE/LiOAr (first-generation catalyst), which required a tedious catalyst preparation process. In the reaction with the second-generation catalyst, the intermediate Cu-aldolate functioned as a Bronsted base to generate thioamide enolate, efficiently driving the catalytic cycle. The present aldol methodol. culminated in a concise asym. synthesis of atorvastatin I (Lipitor: atorvastatin calcium), a widely prescribed HMG-CoA reductase inhibitor for lowering low-d. lipoprotein cholesterol.

Here is just a brief introduction to this compound(75732-01-3)Reference of Mesitylcopper(I), more information about the compound(Mesitylcopper(I)) is in the article, you can click the link below.

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: (2S)-(+)-3-Chloropropane-1,2-diol, is researched, Molecular C3H7ClO2, CAS is 60827-45-4, about Activities of various 6-chloro-6-deoxysugars and (S)α-chlorohydrin in producing spermatocoeles in rats and paralysis in mice and in inhibiting glucose metabolism in bull spermatozoa in vitro, the main research direction is contraceptive male chlorodeoxy sugar; chlorohydrin male contraceptive; toxicity male contraceptive chlorodeoxysugar.Synthetic Route of C3H7ClO2.

6-chloro-6-deoxyglucose (I) [40656-44-8], 6-chloro-6-deoxymannose  [4990-81-2], 6-chloro-6-deoxyfructose  [66451-66-9], 6-chloro-6-deoxyglucitol  [76986-26-0], 6-chloro-6-deoxygalactose  [18465-32-2], and (S)α-chlorohydrin  [60827-45-4] all produced spermatoceles in the efferent ducts and epididymis of the rat and were neurotoxic in the mouse, but only α-chlorohydrin caused substantial inhibition of D-glucose  [50-99-7] metabolism in bull spermatozoa in vitro. The relative potencies of the compounds in producing spermatoceles reflected their activities as reversible antifertility agents in the rat but compared to the others 6-chloro-6-deoxymannose was considerably less neurotoxic to mice than might have been anticipated from its contraceptive dose. Thus, different metabolites may be responsible for causing the antifertility and the neurotoxic effects.

Here is just a brief introduction to this compound(60827-45-4)Synthetic Route of C3H7ClO2, more information about the compound((2S)-(+)-3-Chloropropane-1,2-diol) is in the article, you can click the link below.

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Reference of Mesitylcopper(I). The mechanism of aromatic electrophilic substitution of aromatic heterocycles is consistent with that of benzene. Compound: Mesitylcopper(I), is researched, Molecular C9H11Cu, CAS is 75732-01-3, about Synthesis of novel copper-rare earth BINOLate frameworks from a hydrogen bonding DBU-H rare earth BINOLate complex. Author is Panetti, Grace B.; Robinson, Jerome R.; Carroll, Patrick J.; Gau, Michael R.; Manor, Brain C.; Walsh, Patrick J.; Schelter, Eric J..

The preparation of a novel H-bonding DBU-H+ BINOLate Rare Earth Metal complex [RE(S-binol)3·3DBU-H, where RE = La, Pr, and Eu; DBU = 1,8-Diazabicyclo(5.4.0)undec-7-ene] enabled the synthesis of the first copper-Rare Earth Metal BINOLate complex (CuDBU-REMB, Cu3RE(S-binol)3(DBU)3). CuDBU-REMB was compared to the analogous Li complex using x-ray crystallog. and Exchange NMR spectroscopy (EXSY). The results provide insight into the role of the secondary metal cation in the framework’s stabilization.

Here is just a brief introduction to this compound(75732-01-3)Reference of Mesitylcopper(I), more information about the compound(Mesitylcopper(I)) is in the article, you can click the link below.

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

COA of Formula: C9H11Cu. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: Mesitylcopper(I), is researched, Molecular C9H11Cu, CAS is 75732-01-3, about Preparation and characterization of copper(I) amides. Author is Tsuda, Tetsuo; Watanabe, Katsuhiko; Miyata, Kazuyoshi; Yamamoto, Hirotsugu; Saegusa, Takeo.

Cu(I) amides, CuNRR’, were prepared by the reaction of mesitylcopper(I) with RR’NH and characterized by chem. and thermal analyses. CuNRR’ react with CO2 in C6H6 in presence of tert-BuNC to give RR’NCO2Cu.(tert-Bu-NC)n, which with MeI give RR’NCO2Me.

Here is just a brief introduction to this compound(75732-01-3)COA of Formula: C9H11Cu, more information about the compound(Mesitylcopper(I)) is in the article, you can click the link below.

Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com