Tag: M.W=200-250

Metzger, Juergen O. published the artcileRadical additions of activated haloalkanes to alkenes initiated by electron transfer from copper in solvent-free systems, Product Details of C5H9IO2, the publication is Angewandte Chemie, International Edition in English (1995), 34(8), 902-4, database is CAplus.

The solventless first radical addition of alkyl α-iodocarboxylates or α-iodoalkanenitriles to alkenes over copper metal involves an electron transfer initiated mechanism. The synthetic utility of this method is discussed.

Angewandte Chemie, International Edition in English published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Product Details of C5H9IO2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Metzger, Jurgen O. published the artcileRadical additions of alkyl 2-haloalkanoates and 2-haloalkanenitriles to alkenes initiated by electron transfer from copper in solvent-free systems, COA of Formula: C5H9IO2, the publication is Liebigs Annalen/Recueil (1997), 2303-2313, database is CAplus.

Alkyl 2-iodoalkanoates and 2-iodoalkanenitriles were added with Cu powder to the 1-alkenes RCH₂CH:CH₂ [R = (CH₂)₇CO₂Me, (CH₂)₄Me, OH, C(CO₂Et)₂CH₂CH:CH₂] and to the alkenes (Z)-R(CH₂)₂CH:CH(CH₂)₂R¹ [R = (CH₂)₅Me, R¹ = (CH₂)₅CO₂Me; R = (CH₂)₅Me, R¹ = (CH₂)₉CO₂Me; R = (CH₂)₈Me, R¹ = (CH₂)₂CO₂Me; RR¹ = bond] to give γ-lactones and 4-iodoalkanenitriles, resp., in very good yields. No solvent was used. The reaction is a free-radical addition initiated by electron transfer from Cu to the activated iodoalkane. Yields were lower using the resp. bromo compounds In-situ formation of the iodo compounds by addition of stoichiometric amounts of NaI to the reaction mixture gave improved yields. In the case of bromomalonates, the addition of NaI proved to be unnecessary. The diastereoselectivity of the addition reaction by relative 1,3-asym. induction was rationalized by consideration of the steric interactions of the substituents in the transition state which is formed in the process of I transfer to the chiral adduct radical.

Liebigs Annalen/Recueil published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, COA of Formula: C5H9IO2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Das, Sanju published the artcileSynthesis of Polysubstituted Quinolines from α-2-Aminoaryl Alcohols Via Nickel-Catalyzed Dehydrogenative Coupling, Quality Control of 53279-83-7, the publication is Journal of Organic Chemistry (2018), 83(4), 2309-2316, database is CAplus and MEDLINE.

This study reports a nickel-catalyzed sustainable synthesis of polysubstituted quinolines, e.g. I, from α-2-aminoaryl alcs. by a sequential dehydrogenation and condensation process that offers the advantages of a low catalyst loading and wide substrate scope. In contrast to earlier reported methods, this strategy allows the use of both primary as well as secondary α-2-aminoaryl alcs. in combination with either ketones or secondary alcs. for desired product formation. Using this methodol., 30 substituted quinoline derivatives were synthesized with up to 93% isolated yields.

Journal of Organic Chemistry published new progress about 53279-83-7. 53279-83-7 belongs to iodides-buliding-blocks, auxiliary class Iodide,Amine,Benzene,Alcohol, name is (2-Amino-5-iodophenyl)methanol, and the molecular formula is C7H8INO, Quality Control of 53279-83-7.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Radwan, Ahmed S. published the artcileSynthesis, characterization, and self-assembly of fluorescent fluorine-containing liquid crystals, COA of Formula: C6H13I, the publication is Luminescence (2021), 36(7), 1751-1760, database is CAplus and MEDLINE.

In the current work, the synthesis, self-assembly, and mesogenic properties of new perfluorinated para-terphenyls bearing various para-substituted alkoxy and thioalkoxy chains was described. The terphenyl core was prepared using Cu(I) (or Cu(I)/phenanthroline)-catalyzed decarboxylative carbon-carbon (or carbon-oxygen [sulfur]) cross-coupling from the analogous aromatic iodide and fluorobenzoate potassium salt. The mol. structures of the prepared perfluorinated terphenyls were demonstrated with ¹H, ¹³C, and ¹⁹F NMR, as well as FT-IR and X-ray crystallog. The liquid crystalline properties and mesogenic phases were characterized with differential scanning calorimetry and high-resolution polarized optical microscope. Both UV-visible absorbance and emission spectra demonstrated solvatochromism. Supramol. self-assembly of the generated perfluorinated para-terphenyls was monitored by van der Waals and π-π stacking interaction forces. The creation of nanofibrous architectures was monitored by SEM.

Luminescence published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, COA of Formula: C6H13I.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wang, Fei published the artcileTransition-metal- and phosphorus-free electrophilic trifluoromethylthiolation of indoles with sodium trifluoromethanesulfinate in ionic liquids, Recommanded Product: 1-Iodohexane, the publication is Tetrahedron Letters (2021), 153015, database is CAplus.

An acid-promoted protocol has been developed to achieve the transition-metal- and phosphorus-free electrophilic trifluoromethylthiolation of indoles I (R = H, 4-Me, 5-benzyloxy, 6-F, etc.; R¹ = H, Me, Et; R² = H, Ph) using sodium trifluoromethanesulfinate in an imidazolium-based ionic liquid ([Hmim]Br) to obtain subtd. ((trifluoromethyl)thio)-1H-indole derivatives II. The [Hmim]Br not only acts as a recyclable solvent, but also as the reductant in this transformation. The advantages of this chem. include simple operation, use of a recyclable solvent, avoidance of transition-metal and phosphorus, and gram-scale synthesis.

Tetrahedron Letters published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C9H9F5Si, Recommanded Product: 1-Iodohexane.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Ting-Ting published the artcileElectrochemical Alkoxyhalogenation of Alkenes with Organohalides as the Halide Sources via Dehalogenation, Quality Control of 31253-08-4, the publication is Organic Letters (2020), 22(18), 7250-7254, database is CAplus and MEDLINE.

A general, ideal atom use electrochem. technol. to enable alkene alkoxyhalogenation and organohalide dehalogenation in one pot is presented. This technol. is highlighted by convergent strategy integrating several reactions, such as alkene alkoxyhalogenation, organohalide dehalogenation, and dehalogenation deuteration. Exptl. data suggest that alkenes have the lowest oxidation potential, which lead to anodic conversion of the C=C bond to the radical cation intermediates, and cathodic transformations of organohalides, including alkyl and aryl halides, as the nucleophilic halogen sources.

Organic Letters published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C7H7BClFO3, Quality Control of 31253-08-4.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Metzger, Juergen O. published the artcileRadical additions of activated haloalkanes to alkenes initiated by electron transfer from copper in solvent-free systems, Product Details of C5H9IO2, the publication is Angewandte Chemie, International Edition in English (1995), 34(8), 902-4, database is CAplus.

The solventless first radical addition of alkyl α-iodocarboxylates or α-iodoalkanenitriles to alkenes over copper metal involves an electron transfer initiated mechanism. The synthetic utility of this method is discussed.

Angewandte Chemie, International Edition in English published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Product Details of C5H9IO2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Metzger, Jurgen O. published the artcileRadical additions of alkyl 2-haloalkanoates and 2-haloalkanenitriles to alkenes initiated by electron transfer from copper in solvent-free systems, COA of Formula: C5H9IO2, the publication is Liebigs Annalen/Recueil (1997), 2303-2313, database is CAplus.

Alkyl 2-iodoalkanoates and 2-iodoalkanenitriles were added with Cu powder to the 1-alkenes RCH₂CH:CH₂ [R = (CH₂)₇CO₂Me, (CH₂)₄Me, OH, C(CO₂Et)₂CH₂CH:CH₂] and to the alkenes (Z)-R(CH₂)₂CH:CH(CH₂)₂R¹ [R = (CH₂)₅Me, R¹ = (CH₂)₅CO₂Me; R = (CH₂)₅Me, R¹ = (CH₂)₉CO₂Me; R = (CH₂)₈Me, R¹ = (CH₂)₂CO₂Me; RR¹ = bond] to give γ-lactones and 4-iodoalkanenitriles, resp., in very good yields. No solvent was used. The reaction is a free-radical addition initiated by electron transfer from Cu to the activated iodoalkane. Yields were lower using the resp. bromo compounds In-situ formation of the iodo compounds by addition of stoichiometric amounts of NaI to the reaction mixture gave improved yields. In the case of bromomalonates, the addition of NaI proved to be unnecessary. The diastereoselectivity of the addition reaction by relative 1,3-asym. induction was rationalized by consideration of the steric interactions of the substituents in the transition state which is formed in the process of I transfer to the chiral adduct radical.

Liebigs Annalen/Recueil published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, COA of Formula: C5H9IO2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Pan, Zhangjin published the artcilePalladium/TY-Phos-Catalyzed Asymmetric Intermolecular α-Arylation of Aldehydes with Aryl Bromides, Product Details of C6H13I, the publication is Angewandte Chemie, International Edition (2021), 60(34), 18542-18546, database is CAplus and MEDLINE.

Herein, an efficient Pd-catalyzed asym. intermol. α-arylation reaction of α-alkyl-α-aryl disubstituted aldehydes with aryl bromides, which provided a rapid access to chiral aldehydes bearing an α-all-carbon quaternary stereocenter in moderate to good yields with good er in most cases was reported. In addition, a pair of enantiomers could be easily prepared with the use of the same ligand by exchanging the aryl groups of aldehyde and aryl bromide.

Angewandte Chemie, International Edition published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Product Details of C6H13I.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Deng, Weili published the artcileIron-Catalyzed Carboiodination of Alkynes, HPLC of Formula: 31253-08-4, the publication is Synthesis (2018), 50(15), 2974-2980, database is CAplus.

An iron-catalyzed carboiodination of alkynes/aliphatic alkenes with alkyl iodides at room temperature was developed to afford vinyl iodides I [R¹ = Ac, CO₂Et, Ph, etc.; R² = CH₂CN, CF₂CO₂Et, cyclohexyl, etc.] and secondary alkyl iodides II [R³ = n-hexyl, Bn, 4-FC₆H₄CH₂, CH₂CH₂Ph; R⁴ = CF₂CF₃, CF₂CO₂Et, FCH(CF₃)₂] resp. This method could provided synthetically useful vinyl iodides with general alkyl chains, fluoroalkyl group, ester and cyano group. Conjugated alkynes or unconjugated alkynes were both suitable for this transformation. A radical pathway was proposed for the mechanism and acetyl tert-Bu peroxide was selected as the radical initiator. Alkenes could also be applied to this chem. and produce more complex alkyl iodides.

Synthesis published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, HPLC of Formula: 31253-08-4.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com