Tag: M.W=200-250

Schaedel, Nicole published the artcileSynthesis of imidazole and histidine-derived cross-linkers as analogs of GOLD and Desmosine, Application of 1-Iodohexane, the publication is Synthesis (2021), 53(13), 2260-2268, database is CAplus.

Amino acid derivatives with a central cationic heterocyclic core (e.g., imidazolium) are biol. relevant cross-linkers of proteins and advanced glycation end (AGE) products. Here, imidazolium-containing cross-linkers were synthesized from imidazole or histidine by N-alkylation employing aspartate- and glutamate-derived mesylates as key step. Biol. investigations were carried out to probe the biocompatibility of these compounds

Synthesis published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Application of 1-Iodohexane.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Li, Xiaoya published the artcileNonionic nontoxic antimicrobial polymers: indole-grafted poly(vinyl alcohol) with pendant alkyl or ether groups, Product Details of C6H13I, the publication is Polymer Chemistry (2022), 13(16), 2307-2319, database is CAplus.

A series of new nonionic antimicrobial polymers with a biodegradable polyvinyl alc. (PVA) backbone grafted with indole units and different hydrophobic alkyl or ether groups were synthesized by facile esterification. The chem. structures and thermal properties of the obtained polymers were characterized by GPC, NMR, FTIR, WAXD, TGA and DSC analyses. All these nonionic polymers showed a significant antibacterial effect similar to gentamicin against 9 food and human pathogenic bacteria according to the disk diffusion assay. The presence of alkyl or ether groups in most cases did not significantly affect the antibacterial effect compared to the polymer with unsubstituted indole units (with N-H moieties). The impacts of the OH conversion and mol. weight of the obtained polymers on their antimicrobial and anti-quorum sensing effects were also preliminarily investigated. Finally, the obtained indole-grafted PVAs were subjected to MTT assay using a mammalian cell line and hemolysis investigations, and the results showed excellent biocompatibility, particularly for those with ether substituents.

Polymer Chemistry published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Product Details of C6H13I.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Piccialli, Vincenzo published the artcileBromination and iodination of donor-acceptor cyclopropanes. Evidence for an ET mechanism, Formula: C5H5ClIN, the publication is Tetrahedron Letters (2002), 43(45), 8067-8070, database is CAplus.

Et 2,2-dimethoxycyclopropanecarboxylates 1a-d react easily with Br₂ and I₂ in CCl₄ or CH₂Cl₂ leading, in high yields, to 1-ethyl- or 4-methyl-2-halobutanedioates 2 and 3, resp. Bromination in the presence of pyridine, NBS, tri-Me phosphate, and iodination with ICl and ICl/pyridine was also performed. A common SET mechanism may be proposed for both halogenations; depending on the reaction conditions, bromination can also occur via acid-catalyzed or S_E2 routes. The reaction of the 2-ethoxy analogs cis-12 and trans-12 with the same halogens proceeds in a similar manner, giving 3-formyl-2-halo esters along with the corresponding diethylacetals as main products. Iodination of 12 with the catalytic system NaI/m-CPBA/18-crown-6 also was studied.

Tetrahedron Letters published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, Formula: C5H5ClIN.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Fialkov, Ya. A. published the artcileComplex formation by trihydroxyglutaric acid with some metals. I. Complex formation of trihydroxyglutaric acid with trivalent iron, SDS of cas: 6443-90-9, the publication is Zhurnal Neorganicheskoi Khimii (1956), 2504-16, database is CAplus.

Optically inactive trihydroxyglutaric acid (I) reacts with aqueous Fe(NO₃)₃ to form a Fe-bearing anion. From experiments carried out at low pH values (<2) and from equilibrium studies of Fe sal⁺ (where sal is the bivalent salicylate radical) with I at pH = 3, and of Fe sal₂^– with the disodium salt of I (at pH = 6), optical d. and elec.-cond data were obtained which supported the hypothesis of a complex in which the Fe:I ratio was 1:1. At low pH values the principal species is H[FeC₅H₄O₇]. At pH = 6, the anion [FeC₅H₄O₇]^– is characteristic, whereas at pH = 10, the anion becomes [FeC₅H₃O₇]^—. The equilibrium constant for the reaction [FeC₅H₄O₇]^– + 2H⁺ â†?C₅H₆O₇^— + Fe⁺⁺⁺ is 0.12. At about pH = 6, the trihydroxyglutarate complex of Fe⁺⁺⁺ is probably more stable than is the corresponding tartrate complex.

Zhurnal Neorganicheskoi Khimii published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, SDS of cas: 6443-90-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Saiter, Jeremy published the artcileDirect Trifluoromethoxylation without OCF₃-Carrier through In Situ Generation of Fluorophosgene, Formula: C5H9IO2, the publication is European Journal of Organic Chemistry (2021), 2021(22), 3139-3147, database is CAplus.

The method represented the preparation of a range of trifluoromethoxylated structures R-OCF₃ [R = undecanyl, (CH₂)₂Ph, 4-BrC₆H₄CH₂, etc.] with no use of an intermediate trifluoromethoxylating reagent, but in situ construction and use of the F₃CO anion as a salt, avoiding the presence of a useless side-product resulting from activation of an OCF₃ carrier.

European Journal of Organic Chemistry published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Formula: C5H9IO2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Bowmaker, G. A. published the artcileNuclear quadrupole resonance of charge-transfer complexes. II. Amine-halogen complexes, COA of Formula: C5H5ClIN, the publication is Australian Journal of Chemistry (1969), 22(10), 2047-59, database is CAplus.

Nuclear quadrupole resonance frequencies have been measured for some of the halogen nuclei in a number of crystalline charge-transfer complexes of amines with bromide, I, IBr, and ICl. From these measurements it has been possible to calculate approx. charge distributions for the Br, IBr, and ICl complexes of 3,5-dibromopyridine. The results correlate well with a three-center delocalized L.C.A.O.-M.O. bonding theory. The correlation of this M.O. description with Mulliken’s charge-transfer bonding scheme for n-σ complexes is discussed. This approach indicates the importance of considering an “ionic” structure (which does not involve transfer of charge from the donor to the acceptor) in the electronic ground state of these complexes.

Australian Journal of Chemistry published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, COA of Formula: C5H5ClIN.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Maeda, Yoshiaki published the artcilePractical Asymmetric Synthesis of Chiral Sulfoximines via Sulfur-Selective Alkylation, Safety of 1-Iodohexane, the publication is Journal of Organic Chemistry, database is CAplus and MEDLINE.

Herein, an asym. synthesis of chiral sulfoximines RS(=NPiv)(O)C(CH₃)₃ (R = Me, i-Bu, 4-(1,3-dioxolan-2-yl)butyl, etc.) through a stereospecific S-alkylation of readily accessible 2,2-dimethyl-N-[(S)-2-methylpropane-2-sulfinyl]propanamide under practical conditions was demonstrated. A key to establishing the practical conditions was the identification of the intermediate structure in the previously reported S-alkylation by X-ray crystallog. anal.

Journal of Organic Chemistry published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Safety of 1-Iodohexane.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhang, Jianbo published the artcileSynthesis of 2-Quinolinones through Palladium(II) Acetate Catalyzed Cyclization of N-(2-Formylaryl)alkynamides, Name: (2-Amino-5-iodophenyl)methanol, the publication is Synlett (2015), 26(12), 1744-1748, database is CAplus.

A Pd(OAc)₂-catalyzed cyclization of N-(2-formylaryl)alkynamides initiated by the oxypalladation of alkynes was developed. The method provides a new approach for the efficient and atom-economical synthesis of 2-quinolinone derivatives

Synlett published new progress about 53279-83-7. 53279-83-7 belongs to iodides-buliding-blocks, auxiliary class Iodide,Amine,Benzene,Alcohol, name is (2-Amino-5-iodophenyl)methanol, and the molecular formula is C15H14O3, Name: (2-Amino-5-iodophenyl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Fleming, H. Creswell published the artcileNuclear quadrupole resonance investigation of iodine monochloride complexed with pyridines, Synthetic Route of 6443-90-9, the publication is Journal of the American Chemical Society (1971), 93(20), 5030-4, database is CAplus.

The 35Cl and 127I nuclear quadrupole resonance absorption frequencies of pyridine-ICl and 4-methylpyridine-ICI was measured as a function of temperature Their resp. values at 273.2°K are 21.136 ± 0.01, 21.175 ± 0.01, 464.28 ± 0.04, and 462.76 ± 0.04 MHz. Their temperature coefficients were +2.2, +2.5, – 28, and – 24 kHz/°K. Application of the Townes and Dailey theory with neglect of s hydridization at the halogen atoms results in the following charge ds. in each complex: pyridine (or 4-methylpyridine) +0.26; I +0.35; and Cl – 0.61 electron. A valence-bond interpretation indicates a 57% contribution of the “nobond” wave function to the ground state. A representation in which the charge-transfer and electrostatic wave functions are explicitly included contains a maximum of 26% charge-transfer character in the ground-state wave function. Classical electrostatic forces thus appear to play a dominant role in the stabilization of these complexes. The charge-transfer contributions are nonnegligible, but a representation of the complex structure based completely on the chargetransfer model is likely to give misleading results.

Journal of the American Chemical Society published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, Synthetic Route of 6443-90-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Gunaratna, Medha J. published the artcileSynthesis of probe molecules, 6-(dimethylamino)-2-phenylisoindolin-1-ones, for mechanistic studies of firefly luciferase inhibition, Application of (2-Amino-5-iodophenyl)methanol, the publication is Heterocycles (2021), 103(1), 231-248, database is CAplus and MEDLINE.

In order to probe firefly luciferase inhibition’s mechanism, we synthesized two probe mols. I and II, mimicking F-53. Mol. I contains an azido-appended side chain in the aromatic ring of F-53, while 2 possesses an azido and a carboxylic acid group appended side chains. Both synthetic schemes are readily amenable to large-scale syntheses. Mol. I was made from 2-allylaniline, which was derived from a thermal-induced aromatic-Claisen rearrangement of N-allylaniline. The azido-appended side chain of II was installed from a Horner-Wadsworth-Emmons reaction and the carboxylic acid side chain from a Sonogashira reaction.

Heterocycles published new progress about 53279-83-7. 53279-83-7 belongs to iodides-buliding-blocks, auxiliary class Iodide,Amine,Benzene,Alcohol, name is (2-Amino-5-iodophenyl)methanol, and the molecular formula is C7H8INO, Application of (2-Amino-5-iodophenyl)methanol.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com