Tag: M.W=200-250

Abdullah, Mahmood M. S. published the artcileNew Amphiphilic Ionic Liquids for the Demulsification of Water-in-Heavy Crude Oil Emulsion, Safety of 1-Iodohexane, the publication is Molecules (2022), 27(10), 3238, database is CAplus and MEDLINE.

This work aimed to use abietic acid (AA), as a widely available natural product, as a precursor for the synthesis of two new amphiphilic ionic liquids (AILs) and apply them as effective demulsifiers for water-in-crude oil (W/O) emulsions. AA was esterified using tetraethylene glycol (TEG) in the presence of p-toluene sulfonic acid (PTSA) as a catalyst obtaining the corresponding ester (AATG). AATG was reacted with 1-vinylimidazole (VIM) throughout the Diels-Alder reaction, forming the corresponding adduct (ATI). Following this, ATI was quaternized using alkyl iodides, Et iodide (EI) and hexyl iodide (HI) to obtain the corresponding AILs, ATEI-IL and ATHI-IL, resp. The chem. structure, surface activity, thermal stability and relative solubility number (RSN) were investigated using different techniques. The efficiency of ATEI-IL and ATHI-IL to demulsify W/O emulsions in different crude oil: brine volumetric ratios were evaluated. ATEI-IL and ATHI-IL achieved promising results as demulsifiers. Their demulsification efficiency increased as the brine ratios decreased where their efficiency reached 100% at the crude oil: brine ratio (90:10), even at low concentrations

Molecules published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Safety of 1-Iodohexane.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Liu, Shengqin published the artcileHighly selective production of propionic acid from lactic acid catalyzed by NaI, Product Details of C5H9IO2, the publication is Green Chemistry (2020), 22(21), 7468-7475, database is CAplus.

Propionic acid (PA), a valuable chem. widely used in the food and feed industry, is currently produced by the petrochem. industry. Selective production of PA from bio-based lactic acid (LA) is difficult due to the high activation energy of the hydroxyl group at the α position of the carboxyl group. Herein, a metal-free catalytic system for the highly selective transformation of bio-based LA to PA, which was used as the solvent to simplify the separation step, is reported using NaI as the catalyst. Under the optimal reaction conditions, a > 99% yield of PA can be obtained from LA. A heat-induced radical-activated hydrogen mechanism was proposed based on the kinetic study and intermediate capture. The metal-free system can be reused five times without any loss in activity, and the PA product is easily separated In addition, a two-step method using cellulose as the raw material to produce PA was conducted. This strategy offers a green and efficient approach to synthesize PA from biomass resources.

Green Chemistry published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Product Details of C5H9IO2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chen, Chia-Yuan published the artcileTerpyridyl ruthenium complexes functionalized with conjugated heterocycles for panchromatic dye-sensitized solar cells, COA of Formula: C6H13I, the publication is ACS Applied Energy Materials (2021), 4(12), 13461-13470, database is CAplus.

Photosensitizer, a key component of dye-sensitized solar cells (DSCs), significantly affects the power conversion efficiency (PCE) of the devices. In this study, three terpyridyl (tpy) ruthenium complex dyes incorporating hexyl-substituted pyrrole (CYC-36), 4-methylthiazole (CYC-39), and thieno[3,2-b]pyrrole (CYC-41) were designed and their photovoltaic performance was examined To the best of our knowledge, this study introduced these heterocyclic conjugated rings to functionalize the tpy-coordinated ruthenium complexes and discovered that 4-methylthiazole in the anchoring ligand of CYC-39 simultaneously enhanced the lighting-harvesting capability of the dye mol., increased dye-loading in TiO₂ photoanode, and reduced the charge recombination in the cells. The multifunction of 4-methylthiazole moiety is ascribed to not only the aromaticity and electron-withdrawing nature but also the formation of a moderate dihedral angle between the thiazole ring and the tpy core. Consequently, the DSC device sensitized with CYC-39 yields not only a panchromatic response up to 900 nm but also a good PCE of 9.0%.

ACS Applied Energy Materials published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, COA of Formula: C6H13I.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zappi, Enrique V. published the artcileCombinations of iodine trichloride with pyridine, quinoline and trimethylamine, Synthetic Route of 6443-90-9, the publication is Anales de la Asociacion Quimica Argentina (1921-2001) (1939), 102-26, database is CAplus.

Chloroiodides and trichloroiodides of pyridine, quinoline and NMe₃, and their hydrates have, as regards a given group, the curious property of changing from one to the other by simple chem. reactions and appear to be not true complexes formed about the same central atom, but addition compounds of ICl and ICl₃ with tertiary anhydrous bases, which, by the action of acids or H₂O, are converted into true salts of the NH₄ type with HICl₂ and HICl₄.

Anales de la Asociacion Quimica Argentina (1921-2001) published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C12H15BF2O2, Synthetic Route of 6443-90-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Gomes, Vanessa S. D. published the artcileSquaraine Dyes Derived from Indolenine and Benzo[e]indole as Potential Fluorescent Probes for HSA Detection and Antifungal Agents, Application of 1-Iodohexane, the publication is Photochemistry and Photobiology, database is CAplus and MEDLINE.

Four squaraine dyes derived from 2,3,3-trimethylindolenine and 1,1,2-trimethyl-1H-benzo[e]indole with different combinations of barbituric groups attach to the central ring, having ester groups and alkyl chains in the nitrogen atoms of heterocyclic rings were synthesized. These dyes were fully characterized, and their photophys. behavior was studied in ethanol and phosphate-buffered solution Absorption and emission bands between 631 and 712 nm were detected, with the formation of aggregates in aqueous media, which is typical of this class of dyes. Tests carried out with 1,3-diphenylisobenzofuran allowed us to verify the ability of the dyes to produce singlet oxygen. The interaction of synthesized dyes with human serum albumin (HSA) was also evaluated, being demonstrated a linear correlation between fluorescence intensity and protein concentration The antifungal potential of the dyes against the yeast Saccharomyces cerevisiae was evaluated using a broth microdilution assay. In order to test the photosensitizing capacity of the synthesized dyes, tests were carried out in the dark and with irradiation, using a custom-built light-emitting diode that emits close to the absorption wavelength of the studied dyes. The results showed that the interaction of dyes with HSA and the antifungal activity depends on the different structural modifications of the dyes.

Photochemistry and Photobiology published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Application of 1-Iodohexane.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Polo-Cuadrado, Efrain published the artcileSingle crystal structure, thermal stability and theoretical studies of ethyl 4-(4-(dimethylamino)phenyl)-3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate, Synthetic Route of 638-45-9, the publication is Journal of Molecular Structure (2022), 132826, database is CAplus.

Et 4-(4-(dimethylamino)phenyl)-3,6-dimethyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (5) was synthesized according to our previously reported procedure in a 92% yield and crystallized by a slow evaporation technique. This report describes the in-depth structural anal. thereof. The structural characterization and purity of the title compound were determined by UV-vis, FT-IR, ¹H NMR, and ¹³C NMR spectroscopy, high-resolution mass spectrometry (HRMS), thermogravimetric anal. (TG/DTG), and its 3D-structure was confirmed by single-crystal X-ray diffraction. The synthesized title mol. crystallized in the triclinic space group P-1, Z = 2. In the crystal packing, the cohesion among the different mols. is assured by one C-H···O hydrogen bond interaction. Hirshfeld surface anal. indicated that H···H bond interactions are the primary contributors to the intermol. stabilization in the crystal.

Journal of Molecular Structure published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Synthetic Route of 638-45-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Meissner, Stefanie A. published the artcileNanoscale π-conjugated ladders, Formula: C6H13I, the publication is Nature Communications (2021), 12(1), 6614, database is CAplus and MEDLINE.

It is challenging to increase the rigidity of a macromol. while maintaining solubility Established strategies rely on templating by dendrons, or by encapsulation in macrocycles, and exploit supramol. arrangements with limited robustness. Covalently bonded structures have entailed intramol. coupling of units to resemble the structure of an alternating tread ladder with rungs composed of a covalent bond. We introduce a versatile concept of rigidification in which two rigid-rod polymer chains are repeatedly covalently associated along their contour by stiff mol. connectors. This approach yields almost perfect ladder structures with two well-defined π-conjugated rails and discretely spaced nanoscale rungs, easily visualized by scanning tunnelling microscopy. The enhancement of mol. rigidity is confirmed by the fluorescence depolarization dynamics and complemented by mol.-dynamics simulations. The covalent templating of the rods leads to self-rigidification that gives rise to intramol. electronic coupling, enhancing excitonic coherence. The mols. are characterized by unprecedented excitonic mobility, giving rise to excitonic interactions on length scales exceeding 100 nm. Such interactions lead to deterministic single-photon emission from these giant rigid macromols., with potential implications for energy conversion in optoelectronic devices.

Nature Communications published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Formula: C6H13I.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Grunwald, Marco Andre published the artcileMesomorphic properties of cyanobiphenyl dimers with a substituted central malonate unit: overruling effect of fluorination, Formula: C6H13I, the publication is Liquid Crystals (2022), 49(10), 1347-1358, database is CAplus.

Two series of C2-substituted dimers carrying a central C2-hexyl- or C2-nonafluorohexyl malonate and two cyanobiphenyls attached via alkoxy spacers of various lengths I [R = hexyl, nonafluorohexyl; n = 6, 7, 8, etc.] were synthesized, and the mesomorphic properties were studied by differential scanning calorimetry, polarising optical microscopyand X-ray diffraction (wide-angle and small-angle X-ray scattering). The C2-substituent dimers together with the spacer lengths had a pronounced influence on the phase behavior. In case of C2-hexyl-substituted dimers, shorter spacers favored N phases (n = 6-9), while longer spacers favored SmA phases (n �9). In addition, decreased clearing temperatures were observed In contrast, C2-nonafluorohexyl-substituted dimers suppressed N phases and displayed only SmA phases. Moreover, clearing temperatures and phase stabilities considerably increased. Based on the exptl. determined layer thickness, a packing model for the SmA phases was proposed, where C2-substituted dimers displaced mesophases with mols. in a Y-conformation. As a result, less stable mesophases for C2-hexyl-substituted dimers due to weakened intermol. interactions and more stable mesophases for C2-nonafluorohexyl-substituted dimers due to the fluorophobic effect and nanosegregation were obtained.

Liquid Crystals published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Formula: C6H13I.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wang, Chen-Gang published the artcileMetal-Free Fast Azidation by Using Tetrabutylammonium Azide: Effective Synthesis of Alkyl Azides and Well-Defined Azido-End Polymethacrylates, Safety of Ethyl 2-Iodopropionate, the publication is Chemistry – A European Journal (2019), 25(56), 13025-13029, database is CAplus and MEDLINE.

An effective method to synthesize azido-end polymethacrylates from tetrabutylammonium azide (BNN₃) in a nonpolar solvent (toluene) was developed. Several low-mass alkyl halides were reacted with BNN₃ in toluene as model reactions and the rate constants of these reactions were determined, to confirm fast BNN₃ azidation for tertiary and secondary halides. The end-group transformation of halide-end polymethacrylates was effective and nearly quant. Notably, the combination of organocatalyzed living (or reversible deactivation) radical polymerization and BNN₃ azidation enabled the metal-free synthesis of azido-end polymethacrylates, including single-azido-end and multi-azido-end functional homopolymers and block copolymers. The rapid and quant. reaction without the requirement for a large excess of BNN₃, metal-free and polar-solvent-free nature, and broad polymer scope are attractive features of this azidation.

Chemistry – A European Journal published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C8H14O2, Safety of Ethyl 2-Iodopropionate.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Boezio, Alessandro A. published the artcileDiscovery of (R)-6-(1-(8-Fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one (AMG 337), a Potent and Selective Inhibitor of MET with High Unbound Target Coverage and Robust In Vivo Antitumor Activity, COA of Formula: C5H9IO2, the publication is Journal of Medicinal Chemistry (2016), 59(6), 2328-2342, database is CAplus and MEDLINE.

Deregulation of the receptor tyrosine kinase mesenchymal epithelial transition factor (MET) has been implicated in several human cancers and is an attractive target for small mol. drug discovery. Herein, we report the discovery of compound 23 (AMG 337), which demonstrates nanomolar inhibition of MET kinase activity, desirable preclin. pharmacokinetics, significant inhibition of MET phosphorylation in mice, and robust tumor growth inhibition in a MET-dependent mouse efficacy model.

Journal of Medicinal Chemistry published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, COA of Formula: C5H9IO2.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com