Tag: M.W=300-400

Electric Literature of 450412-29-0, The transformation of simple hydrocarbons into more complex and valuable products via catalytic C¨CH bond functionalisation has revolutionised modern synthetic chemistry. 450412-29-0, Name is 1-Bromo-3-fluoro-2-iodobenzene, SMILES is FC1=CC=CC(Br)=C1I, belongs to iodides-buliding-blocks compound. In a article, author is Chen, Guilin, introduce new discover of the category.

A simple and efficient phosphorescent probe for iodide-specific detection based on crystallization-induced phosphorescence of organic ionic crystals

It is very challenging to develop luminescent detection methods for iodide ions due to their significant fluorescence quenching of general fluorophores induced by the heavy-atom effect. Herein, we reveal a unique crystallization-induced bright phosphorescence of tetraphenylphosphonium iodide (TPP I) and develop a novel time-gated detection method for iodide ions to minimize the autofluorescence from complex biological samples. Both the involvement of heavy iodide ion and accessible ionic interaction-induced organic crystals contribute to the accomplishment of a very high phosphorescence quantum yield (0.42) for TPP I. This specific iodide-triggered bright organic phosphorescence enables the development of a novel time-gated detection method for iodide ions in the luminescence turn-on manner and further offers an opportunity to establish a facile test strip for the visual detection of iodide ions based on solid-state phosphorescence on a solid substrate. Excellent performance of this probe in imaging iodide in live cells and intriguing use in double encryption illustrate the versatile and broad application prospects of highly efficient organic ionic crystals in various areas.

Electric Literature of 450412-29-0, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 450412-29-0.

Synthetic Route of 450412-29-0, As an important bridge between the micro and macro material world, chemistry is one of the main methods and means for humans to understand and transform the material world. 450412-29-0, Name is 1-Bromo-3-fluoro-2-iodobenzene, SMILES is FC1=CC=CC(Br)=C1I, belongs to iodides-buliding-blocks compound. In a article, author is Fornaro, Laura, introduce new discover of the category.

Crystalline nanostructures of heavy metal iodides

Heavy metal iodides such as mercuric iodide and bismuth tri-iodide are among the materials with the best properties for room temperature semiconductor detection. The use of nanostructures of these compounds – recently synthesized – as precursors for nucleation of oriented layers, opens new perspectives for layer growth and, through them, the possibility of a new generation of detectors with enhanced imaging performance. The mentioned heavy metal iodides were synthesized in this work in 1-octadecene as solvent, using octadecanethiol (ODT) or trioctylphosphine (TOP) as capping agents. This is the first report of morphology and size control of mercuric iodide and bismuth tri-iodide nanostructures using capping agents. We obtained promising results for mercuric iodide with ODT and for bismuth tri-iodide with TOP, which will start a new trend in nucleation of heavy metal iodides. (C) 2014 Elsevier B.V. All rights reserved.

Synthetic Route of 450412-29-0, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 450412-29-0.

In an article, author is Mezer, E, once mentioned the application of 450412-29-0, Name is 1-Bromo-3-fluoro-2-iodobenzene, molecular formula is C6H3BrFI, molecular weight is 300.8949, MDL number is MFCD07368675, category is iodides-buliding-blocks. Now introduce a scientific discovery about this category, SDS of cas: 450412-29-0.

Echothiophate iodide induced transient hyper- and hypothyroidism

A case of hyper- and hypothyroidism induced by echothiophate iodide eye drops is presented. The thyroid dysfunction was due to excessive iodide intake from the eye drops.

Do you like my blog? If you like, you can also browse other articles about this kind. Thanks for taking the time to read the blog about 450412-29-0, SDS of cas: 450412-29-0.

Chemistry is an experimental science, COA of Formula: C6H3BrFI, and the best way to enjoy it and learn about it is performing experiments.Introducing a new discovery about 450412-29-0, Name is 1-Bromo-3-fluoro-2-iodobenzene, molecular formula is C6H3BrFI, belongs to iodides-buliding-blocks compound. In a document, author is Yuan, R.

Design of Schiff base complexes of Co(II) for the preparation of iodide-selective polymeric membrane electrodes

The response characteristics of some iodide-selective solvent polymeric membrane electrodes based on with N,N’-bis(salicylaldehyde-n-octyl) diimine cobalt(II) (Co(II)SAODI) which is a more lipophilic substitute for a previously reported iodide-carrier are described. The electrode doped with Co(II)SAODI into a plasticized poly(vinyl chloride) membrane exhibits an anti-Hofmeister selectivity pattern with high selectivity toward iodide, long lifetime and small interference from H+. Quartz crystal microgravimetric measurements and ac impedance experiments show that the excellent selectivity for iodide is related to the unique interaction between the carriers and iodide and steric effect associated with the structure of the Schiff base ligands. (C) 1999 Elsevier Science B.V. All rights reserved.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 450412-29-0, in my other articles. COA of Formula: C6H3BrFI.

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 450412-29-0, Name is 1-Bromo-3-fluoro-2-iodobenzene, SMILES is FC1=CC=CC(Br)=C1I, belongs to iodides-buliding-blocks compound. In a document, author is Zhang, L, introduce the new discover, Computed Properties of C6H3BrFI.

Iodide sensitizes genetically modified non-small cell lung cancer cells to ionizing radiation

While external ionizing radiation has been used for treating non-small cell lung cancer (NSCLC), improved efficacy of this modality would be an important advance. Ectopic expression of the sodium iodide symporter (NIS) and thyroperoxidase (TPO) genes in NSCLC cells facilitated concentration of iodide in NSCLC cells, which markedly induced apoptosis in vitro and in vivo. Preincubation of the NIS/TPO-modified NSCLC cells in iodide followed by ionizing radiation generates bystander tumoricidal effects and potently enhances tumor cell killing. This iodide-induced bystander effect is associated with enhanced gap junction intercellular communication (GJIC) activity and increased connexin-43 (Cx43) expression. Thus, iodide may serve as an enhancer to markedly improve the efficacy of radiation therapy in combined therapeutic modalities.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 450412-29-0 is helpful to your research. Computed Properties of C6H3BrFI.

Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology. 450412-29-0, Name is 1-Bromo-3-fluoro-2-iodobenzene, molecular formula is , belongs to iodides-buliding-blocks compound. In a document, author is Li, Pinhua, Category: iodides-buliding-blocks.

A novel silver iodide catalyzed Sonogashira coupling reaction

A novel and efficient Ag-catalyzed Sonogashira coupling reaction has been developed. Terminal alkynes couple with aryl iodides and aryl bromides in the presence of silver iodide, tripbenylphosphine and potassium carbonate to afford the corresponding cross-coupling products in high yields.

Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 450412-29-0, in my other articles. Category: iodides-buliding-blocks.

Reference of 450412-29-0, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 450412-29-0, Name is 1-Bromo-3-fluoro-2-iodobenzene, SMILES is FC1=CC=CC(Br)=C1I, belongs to iodides-buliding-blocks compound. In a article, author is Serrano-Nascimento, Caroline, introduce new discover of the category.

Excess iodide downregulates Na+/I- symporter gene transcription through activation of PI3K/Akt pathway

Transcriptional mechanisms associated with iodide-induced downregulation of NIS expression remain uncertain. Here, we further analyzed the transcriptional regulation of NIS gene expression by excess iodide using PCCl3 cells. NIS promoter activity was reduced in cells treated for 12-24 h with 10(-5) to 10(-3) M NaI. Site-directed mutagenesis of Pax8 and NF-kappa B cis-acting elements abrogated the iodide induced NIS transcription repression. Indeed, excess iodide (10(-3) M) excluded Pax8 from the nucleus, decreased p65 total expression and reduced their transcriptional activity. Importantly, p65-Pax8 physical interaction and binding to NIS upstream enhancer were reduced upon iodide treatment. PI3K/Akt pathway activation by iodide-induced ROS production is involved in the transcriptional repression of NIS expression. In conclusion, the results indicated that excess iodide transcriptionally represses NIS gene expression through the impairment of Pax8 and p65 transcriptional activity. Furthermore, the data presented herein described novel roles for PI3K/Akt signaling pathway and oxidative status in the thyroid autoregulatory phenomenon. 2016 Elsevier Ireland Ltd. All rights reserved.

Reference of 450412-29-0, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 450412-29-0 is helpful to your research.

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 260355-20-2, name is 1-Chloro-4-iodo-2-(trifluoromethyl)benzene, A new synthetic method of this compound is introduced below., Recommanded Product: 260355-20-2

Dissolving 1-chloro-4-iodo-2-trifluoromethylbenzene (10 mmol) obtained in Reaction 1.220 ml of toluene,Isoxazole-4-amine is added sequentially to the system(12mmol),Palladium acetate (0.5 mmol),2,2′-bis(diphenylphosphino)-1,1′-binaphthyl(12 mmol), 3 ml of triethylamine, after stirring for 10 minutes, add 10 ml of cesium carbonate (10 mmol)The aqueous solution is heated to 50 C for 4 hours. After the reaction is completed, 20 ml of water is added to the system.Stir for 20 minutes, dispense,The organic phase is dried over anhydrous sodium sulfate. Concentrated, flash column chromatography,2.2 g of yellow N-(4-chloro-3-trifluoromethylphenyl)-isoxazole-4-amine powder was obtained with a yield of 84%.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; Zhang Ruwei; Ge Baoyin; Jing Fan; (7 pag.)CN108432776; (2018); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Electric Literature of 112671-42-8, The chemical industry reduces the impact on the environment during synthesis 112671-42-8, name is 4-Bromo-1-iodo-2-nitrobenzene, I believe this compound will play a more active role in future production and life.

Intermediate M1-a (3.7 g, 18.6 mmol) and 2-iodo-5-bromonitrobenzene (15.3 g, 46.7 mmol), sodium tert-butoxide (7.1 g, 74.4 mmol), toluene 100 mL, nitrogen, Pd2 (dba) 3 (0.3g), tri-tert-butylphosphine (20ml, 10% in toluene solution), start stirring, heat to 100 C reflux, reaction 12h, the reaction liquid is washed, the organic phase is concentrated, passed the silica gel column, eluent For petroleum ether: ethyl acetate = 50:1, the eluent was concentrated to give intermediate M1-b (9.2 g, yield 82.7%).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Bromo-1-iodo-2-nitrobenzene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Beijing Dingcai Technology Co., Ltd.; Gu’an Dingcai Technology Co., Ltd.; Fan Hongtao; Zhang Yaguang; Zhang Xianghui; Ren Xueyan; (40 pag.)CN108341825; (2018); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Electric Literature of 31827-94-8, A common heterocyclic compound, 31827-94-8, name is 2-Bromo-1-(4-iodophenyl)ethanone, molecular formula is C8H6BrIO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: The appropriate carbonyl compound (50 mmol) was dissolved in 50 mL of ethanol and magnetically stirred with an equimolar quantity of thiosemicarbazide for 24 h at room temperature with catalytic amounts of acetic acid. The desired thiosemicarbazone precipitated from reaction mixture, was filtered, crystallized from suitable solvent, and dried. Equimolar quantities of 4-iodo-acetophenone and bromine, both dissolved in chloroform, were stirred for 4 h at room temperature until the presence of HBr disappeared. The solution was evaporated under vacuum and the obtained pale yellow solid was washed with petroleum ether to give alpha-bromo-4-iodo-acetophenone in good yield (94%). Equimolar amounts of the prepared thiosemicarbazone (50 mmol) and alpha-bromo-4-iodo-acetophenone (50 mmol), both suspended in 50 mL of ethanol, were reacted at room temperature under magnetic stirring for 10 h. The precipitate was filtered and purified by chromatography to give compounds 1-25 in high yield.

The synthetic route of 31827-94-8 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Secci, Daniela; Bizzarri, Bruna; Bolasco, Adriana; Carradori, Simone; D’Ascenzio, Melissa; Rivanera, Daniela; Mari, Emanuela; Polletta, Lucia; Zicari, Alessandra; European Journal of Medicinal Chemistry; vol. 53; (2012); p. 246 – 253;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com