Related Products of 696-41-3, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 696-41-3, name is 3-Iodobenzaldehyde belongs to iodides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
DAST (27mL, 172.41 mmol) was added to a solution of 3-lodo benzaldehyde (lOg, 43.l0mmol) in DCM (l5OmL) at 0C over a period of 10 mm. The RM was warmed to RT and stirred for 19 h.The RM was carefully quenched into ice water and extracted with DCM (2×1 5OmL).The combined organic layer waswashed with sat. NaHCO3 solution, water(lOOmL), brine(lOOmL), dried over Na2SO4 and concentrated toget crude. The crude compound was purified by CC (0-5% EtOAc in PE) to obtain 9.Og (82.5%) of 1-(difluoromethyl)-3-iodobenzene as yellow oil.
The synthetic route of 3-Iodobenzaldehyde has been constantly updated, and we look forward to future research findings.
Reference:
Patent; GRUeNENTHAL GMBH; SCHUNK, Stefan; REICH, Melanie; JAKOB, Florian; DAMANN, Nils; HAURAND, Michael; KLESS, Achim; ROGERS, Marc; SUTTON, Kathy; WO2015/158427; (2015); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com