Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 127654-70-0, name is 1-Chloro-3-fluoro-2-iodobenzene, A new synthetic method of this compound is introduced below., Application In Synthesis of 1-Chloro-3-fluoro-2-iodobenzene
2-Chloro-6-fluoro-iodbenzene (10 g, 39 mmol) is dissolved in sulfuric acid (conc., 17 mL) at 0 C. A mixture of nitric acid (conc, 3.2 mL) and sulfuric acid (conc., 3.2 mL) is added at 0 C. and stirring is continued for 2 h at 25 C. The reaction mixture is poured onto ice. The resulting precipitate is collected, dried and used without further purification for the next step.
The synthetic route of 127654-70-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; Stadtmueller, Heinz; US2013/29993; (2013); A1;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com