In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called A Pseudomonas putida capable of stereoselective hydrolysis of nitriles, published in 1997-02-28, which mentions a compound: 4553-62-2, mainly applied to stereoselective nitrile hydratase amide Pseudomonas; nitrilase stereoselective Pseudomonas, Safety of 2-Methylglutaronitrile.
P. putida NRRL-18668 contains a nitrile hydratase capable of stereoselective hydrolysis of 2-(4-chlorophenyl)-3-methylbutyronitrile at >90% enantiomeric excess (ee) to the (S)-amide. This soil isolate was recovered from enrichments using (R,S)-2-methylglutaronitrile as the sole nitrogen source. Enzyme expression is constitutive and does not show a high level of catabolite repression. The organism is capable of growth on a wide variety of aliphatic mono- and dinitrile compounds The hydrolysis activity on propionitrile is ∼10.3 μmol/h-mg wet cells. The enzyme in cell-free preparations is inhibited by a number of heavy metals, phenylhydrazine, and cyanide. Substrate specificity is broad, with highest rates shown on C4 and C5 aliphatic mononitriles. The strain appears somewhat unusual in its dependence on Co supplementation for maximum enzyme activity and the ability to hydrolyze some aromatic nitriles. This strain is also capable of a 2-step hydrolysis of 2-(4-isobutylphenyl)-propionitrile and 2-(6-methoxy-2-naphthyl)-propionitrile to the (S, with stereoselectivity residing primarily in the aliphatic amidase. This appears to be the 1st description of a stereoselective nitrile hydratase from a gram-neg. organism.
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Reference:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com