Most of the natural products isolated at present are heterocyclic compounds, so heterocyclic compounds occupy an important position in the research of organic chemistry. A compound: 4553-62-2, is researched, SMILESS is N#CC(C)CCC#N, Molecular C6H8N2Journal, Article, Applied Microbiology and Biotechnology called Purification, cloning, sequencing and over-expression in Escherichia coli of a regioselective aliphatic nitrilase from Acidovorax facilis 72W, Author is Chauhan, S.; Wu, S.; Blumerman, S.; Fallon, R. D.; Gavagan, J. E.; DiCosimo, R.; Payne, M. S., the main research direction is aliphatic nitrilase Acidovorax sequence regioselectivity.Name: 2-Methylglutaronitrile.
A regioselective aliphatic nitrilase from Acidovorax facilis 72W was purified and characterized, and the corresponding gene was cloned and sequenced. This nitrilase gene was over-expressed in Escherichia coli, generating a microorganism that efficiently and regioselectively catalyzes the conversion of aliphatic dinitriles to cyanocarboxylic acids. The high yields obtained, mild reaction conditions used, and robustness observed make this biocatalyst suitable for industrial applications.
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Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com