Fang, Mao-Ying; Chen, Li-Ping; Huang, Lin; Fang, Dong-Mei; Chen, Xiao-Zhen; Wang, Bi-Qin; Feng, Chun; Xiang, Shi-Kai published an article in 2021. The article was titled 《Synthesis of Tribenzo[b,d,f]azepines via Palladium-Catalyzed Annulation Reaction of 2-Iodobiphenyls with 2-Halogenoanilines》, and you may find the article in Journal of Organic Chemistry.Product Details of 63069-48-7 The information in the text is summarized as follows:
A palladium-catalyzed annulation reaction of 2-iodobiphenyls with 2-halogenoanilines has been developed. A variety of 2-iodobiphenyls and 2-halogenoanilines can undergo this transformation. Diversified tribenzo[b,d,f]azepine derivatives can be synthesized in moderate to excellent yields according to this method.4-Chloro-2-iodoaniline(cas: 63069-48-7Product Details of 63069-48-7) was used in this study.
4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.Product Details of 63069-48-7
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com