Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Safety of 2-Iodopyridine.
Tao, Xueqin;Long, Ran;Wu, Di;Hu, Yangguang;Qiu, Ganhua;Qi, Zeming;Li, Benxia;Jiang, Ruibin;Xiong, Yujie research published 《 Anchoring Positively Charged Pd Single Atoms in Ordered Porous Ceria to Boost Catalytic Activity and Stability in Suzuki Coupling Reactions》, the research content is summarized as follows. Single-atom (SA) catalysis bridging homogeneous and heterogeneous catalysis offers new opportunities for organic synthesis, but developing SA catalysts with high activity and stability is still a great challenge. A heterogeneous catalyst of Pd SAs anchored in 3D ordered macroporous ceria (Pd-SAs/3DOM-CeO2) was developed through a facile template-assisted pyrolysis method. The high sp. surface area of 3DOM CeO2 facilitates the heavily anchoring of Pd SAs, while the introduction of Pd atoms induces the generation of surface oxygen vacancies and prevents the grain growth of CeO2 support. The Pd-SAs/3DOM-CeO2 catalyst exhibits excellent activity toward Suzuki coupling reactions for a broad scope of substrates under ambient conditions, and the Pd SAs was stabilized in CeO2 in long-term catalytic cycles without leaching or aggregating. Theor. calculations indicate that the CeO2 supported Pd SAs can remarkably reduced the energy barriers of both transmetalation and reductive elimination steps for Suzuki coupling reactions. The strong metal-support interaction contributed to modulating the electronic state and maintaining the stability of Pd SA sites. The work demonstrated an effective strategy to design and synthesize stable single-atom catalysts as well as sheds new light on the origin for enhanced catalysis based on the strong metal-support interactions.
5029-67-4, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., Safety of 2-Iodopyridine
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com