Month: October 2022

Recommanded Product: 4-IodopyridineIn 2021 ,《Multitasking with Chemical Fuel: Dissipative Formation of a Pseudorotaxane Rotor from Five Distinct Components》 appeared in Journal of the American Chemical Society. The author of the article were Ghosh, Amit; Paul, Indrajit; Schmittel, Michael. The article conveys some information:

A 3-fold completive self-sorted library of dynamic motifs was integrated into the design of the pseudorotaxane-based rotor [Zn(2·H+)(3)(4)]2+ operating at k298 = 15.4 kHz. The rotational motion in the five-component device is based on association/dissociation of the pyridyl head of the pseudorotaxane rotator arm between two zinc(II) porphyrin stations. Addition of TFA or 2-cyano-2-phenylpropanoic acid as a chem. fuel to a zinc release system and the loose rotor components 2-4 enabled the liberated zinc(II) ions and protons to act in unison, setting up the rotor through the formation of a heteroleptic zinc complex and a pseudorotaxane linkage. With chem. fuel, the dissipative system was reproducibly pulsed three times without a problem. Due to the double role of the fuel acid, two kinetically distinct processes played a role in both the out-of-equilibrium assembly and disassembly of the rotor, highlighting the complex issues in multitasking of chem. fuels. In addition to this study using 4-Iodopyridine, there are many other studies that have used 4-Iodopyridine(cas: 15854-87-2Recommanded Product: 4-Iodopyridine) was used in this study.

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Recommanded Product: 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Name: 4-IodopyridineIn 2019 ,《Influence of Donor-Substituents on Triphenylamine Chromophores Bearing Pyridine Fragments》 appeared in European Journal of Organic Chemistry. The author of the article were Tydlitat, Jiri; Feckova, Michaela; le Poul, Pascal; Pytela, Oldrich; Klikar, Milan; Rodriguez-Lopez, Julian; Robin-le Guen, Francoise; Achelle, Sylvain. The article conveys some information:

Efficient synthetic routes that combine different palladium-catalyzed cross-coupling reactions were developed for the preparation of a new family of push-pull derivatives in which pyridine was used as the acceptor group and different para-substituted diphenylamines as the donor groups. All compounds showed absorption in the UV/visible region and blue-green emission with high quantum yields. Significant red shifts were observed in the absorption and fluorescence emission maxima on increasing the electron-donating ability of the substituents or on incorporating a π-conjugated linker. This finding can be explained on the basis of enhanced intramol. charge transfer (ICT). Strong emission solvatochromism confirmed the formation of an intramol. charge-separated emitting state. The HOMO-LUMO energy gaps were estimated by exptl. electrochem. measurements and the results were interpreted with the aid of DFT calculations The thermal behavior of all materials also was studied by DSC. In the experimental materials used by the author, we found 4-Iodopyridine(cas: 15854-87-2Name: 4-Iodopyridine)

4-Iodopyridine(cas: 15854-87-2) is a halogenated heterocycle that is a building block for proteomics research. 4-Iodopyridine is used as a reagent in the synthesis of indazolylamides as glucocorticoid receptor agonists.Name: 4-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Recommanded Product: 1-Iodo-4-methylbenzeneIn 2020 ,《Asymmetric Ni-Catalyzed Radical Relayed Reductive Coupling》 appeared in Journal of the American Chemical Society. The author of the article were Wei, Xiaofeng; Shu, Wei; Garcia-Dominguez, Andres; Merino, Estibaliz; Nevado, Cristina. The article conveys some information:

Alkene dicarbofunctionalizations enable the streamlined construction of aliphatic structures and have thus been the subject of intense research efforts. Despite significant progress, catalytic asym. variants remain scarce. Inspired by the advantages of reductive cross-coupling approaches, we present here a highly efficient asym. intermol. Ni-catalyzed reductive dicarbofunctionalization of alkenes. Two distinct readily available electrophiles, namely, Csp2- and Csp3-halides, are added simultaneously across a variety of olefins (vinyl amides, vinyl boranes, vinyl phosphonates) at room temperature in a highly regio- and enantioselective manner. The reaction, devoid of sensitive organometallic reagents, takes advantage of an in situ generated chiral alkyl Ni(III)-intermediate to ensure a stereodefined outcome in the Csp3-Csp2 bond-forming reaction. An (L)-(+)-isoleucine chiral bisoxazoline ligand and the presence of coordinating sites on the alkene are key for the successful outcome in these “”asym. radical relayed reductive couplings”” (ARRRCs). Further, multiple transformations of the chiral amides obtained in this process showcase the potential of this new methodol. for the straightforward assembly of chiral building blocks such as primary and secondary amines and oxazolines, highlighting its synthetic utility. In the part of experimental materials, we found many familiar compounds, such as 1-Iodo-4-methylbenzene(cas: 624-31-7Recommanded Product: 1-Iodo-4-methylbenzene)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Recommanded Product: 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Application of 591-18-4In 2021 ,《Single-Handed Double Helix and Spiral Platelet Formed by Racemate of Dissymmetric Cages》 was published in Angewandte Chemie, International Edition. The article was written by Liu, Xiaoning; Shi, Zheng; Xie, Mingchen; Xu, Jianping; Zhou, Zhifan; Jung, Sinyeong; Cui, Guijia; Zuo, Yong; Li, Tao; Yu, Chunyang; Liu, Zhiqiang; Zhang, Shaodong. The article contains the following contents:

Spontaneous deracemization has been used to sep. homochiral domains from the racemic system. However, homochirality can only be referred to when the scales of these domains and systems are specified. To clarify this, we report self-assembly of racemates of dissym. cages DC-1 (I) with a cone-shape propeller geometry, forming a centrosym. columnar crystalline phase (racemic at crystallog. level). Owing to their anisotropic geometry, the two enantiomers are packed in a frustrated fashion in this crystalline phase; single-handed double helixes are observed (single-handedness at supramol. level). The frustrated packing (layer continuity break-up) in turn facilitates screw dislocation during the crystal growth, forming left- or right-handed spiral platelets (symmetry-breaking at morphol. level), although each platelet is composed of DC-1 racemates. The symmetry correlation between DC-1 mols., the crystalline phase and spiral platelets, all exhibit C3 symmetry. In addition to this study using 1-Bromo-3-iodobenzene, there are many other studies that have used 1-Bromo-3-iodobenzene(cas: 591-18-4Application of 591-18-4) was used in this study.

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Application of 591-18-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Category: iodides-buliding-blocksIn 2019 ,《Molybdenumhexacarbonyl-Mediated Imino-Carbonylative Acylation of NH-Sulfoximines with Aryl Iodides》 was published in Asian Journal of Organic Chemistry. The article was written by Baranwal, Siddharth; Gupta, Surabhi; Sabiah, Shahulhameed; Kandasamy, Jeyakumar. The article contains the following contents:

Development of a catalyst-free, robust and straightforward iminocarbonylation protocol for the synthesis of N-acyl sulfoximines from sulfoximines and aryl iodides in the presence of Mo(CO)6 has been reported. Simple operation, broad substrate scope, wide functional group tolerance and excellent yields are the salient features of this work. The results came from multiple reactions, including the reaction of 1-Chloro-3-iodobenzene(cas: 625-99-0Category: iodides-buliding-blocks)

1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Electric Literature of C6H4BrIIn 2021 ,《Strong and Confined Acids Catalyze Asymmetric Intramolecular Hydroarylations of Unactivated Olefins with Indoles》 was published in Journal of the American Chemical Society. The article was written by Zhang, Pinglu; Tsuji, Nobuya; Ouyang, Jie; List, Benjamin. The article contains the following contents:

An efficient and highly enantioselective catalytic asym. intramol. hydroarylation of aliphatic and aromatic olefins with indoles e.g., 3-(4-methyleneoctyl)-1H-benzo[g]indole yielding tetrahydrocarbazoles e.g., I can be realized using strong and confined IDPi Bronsted acid catalysts. This unprecedented transformation is enabled by tertiary carbocation formation and establishes quaternary stereogenic centers in excellent enantioselectivity and with a broad substrate scope that includes an aliphatic iodide, an azide, and an alkyl boronate, which can be further elaborated into bioactive mols. The experimental part of the paper was very detailed, including the reaction process of 1-Bromo-3-iodobenzene(cas: 591-18-4Electric Literature of C6H4BrI)

1-Bromo-3-iodobenzene(cas: 591-18-4) has been used in the preparation of 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluorodec-1-ene and 1-(3′-bromophenyl)-3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooct-1-ene.Electric Literature of C6H4BrI

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Recommanded Product: 1-Iodopyrrolidine-2,5-dioneIn 2022 ,《N-Alkylated Analogues of Indolylthio Glycosides as Glycosyl Donors with Enhanced Activation Profile》 was published in European Journal of Organic Chemistry. The article was written by Shrestha, Ganesh; Panza, Matteo; Singh, Yashapal; Stine, Keith J.; Demchenko, Alexei V.. The article contains the following contents:

While studying indolylthio glycosides, previously we determined their activation profile that required large excess of activators. This drawback was partially addressed in the present study of N-alkylated indolylthio glycosides. Also investigated was orthogonality of the indolylthio leaving groups vs. thioglycosides and selective activation of thioimidates over oxindole glycosides. In the experimental materials used by the author, we found 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Recommanded Product: 1-Iodopyrrolidine-2,5-dione)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Recommanded Product: 1-Iodopyrrolidine-2,5-dione

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《An expedient route to tricyanovinylindoles and indolylmaleimides from o-alkynylanilines utilising DMSO as a one-carbon synthon》 was written by Chakraborty, Nikita; Dahiya, Anjali; Rakshit, Amitava; Modi, Anju; Patel, Bhisma K.. Electric Literature of C6H5ClINThis research focused ontricyanovinylindole preparation; alkynyl aniline malononitrile DMSO cascade palladium catalyst copper; indolylmaleimide preparation; phenyl indolyl ethene tricarbonitrile malononitrile cascade palladium catalyst copper. The article conveys some information:

A Pd(II)/Cu(II) catalyzed domino synthesis of tricyanovinylindoles I [R1 = H, 5-Me, 5-F, etc.; R2 = cyclopropyl, Ph, 2-naphthyl, etc.] was synthesized via reaction starting from o-alkynylanilines, malononitrile and utilizing DMSO as a one-carbon synthon. The reaction proceeded via the construction of 2-aryl-3-formyl indoles followed by sequential addition of malononitrile and a CN resulting in two C-C, one C=C and one C-N bonds in the final product. Furthermore, post-synthetic modification of some of the compounds I resulted in the unprecedented formation of 4-cyano-3-indolylmaleimides II [R3 = H, 5-Me, 5-Cl, etc.; R4 = H, 4-F, 4-tBu, etc.]. Photophys. studies of compoundsI [R1 = H, 5-CF3, 5-iPr; R2 = n-Bu, Ph, 4-MeC6H4, 4-F3CC6H4, 2-Br-5-FC6H3, 2-naphthyl] showed emission in the visible range. In the part of experimental materials, we found many familiar compounds, such as 4-Chloro-2-iodoaniline(cas: 63069-48-7Electric Literature of C6H5ClIN)

4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Halogenation, in which one or more hydrogen atoms of an amine is replaced by a halogen atom, occurs with chlorine, bromine, and iodine, as well as with some other reagents, notably hypochlorous acid (HClO). With primary amines the reaction proceeds in two stages, producing N-chloro- and N,N-dichloro-amines, RNHCl and RNCl2, respectively. With tertiary amines, an alkyl group may be displaced by a halogen.Electric Literature of C6H5ClIN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Ligand-Promoted meta-C-H Functionalization of Benzylamines》 was published in Angewandte Chemie, International Edition in 2017. These research results belong to Wang, Peng; Farmer, Marcus E.; Yu, Jin-Quan. Quality Control of 2-Chloro-5-iodo-3-(trifluoromethyl)pyridine The article mentions the following:

Meta-C-H functionalization of benzylamines has been developed using a PdII/transient mediator strategy. Using 2-pyridone ligands and 2-carbomethoxynorbornene (NBE-CO2Me) as the mediator, arylation, amination, and chlorination of benzylamines are realized. This protocol features a broad substrate scope and is compatible with heterocylic coupling partners. Moreover, the loading of the Pd can be lowered to 2.5 mol % by using the optimal ligand. In addition to this study using 2-Chloro-5-iodo-3-(trifluoromethyl)pyridine, there are many other studies that have used 2-Chloro-5-iodo-3-(trifluoromethyl)pyridine(cas: 887707-25-7Quality Control of 2-Chloro-5-iodo-3-(trifluoromethyl)pyridine) was used in this study.

2-Chloro-5-iodo-3-(trifluoromethyl)pyridine(cas: 887707-25-7) belongs to pyridine. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis.Quality Control of 2-Chloro-5-iodo-3-(trifluoromethyl)pyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Strong Visible-Light-Absorbing Cuprous Sensitizers for Dramatically Boosting Photocatalysis》 was written by Chen, Kai-Kai; Guo, Song; Liu, Heyuan; Li, Xiyou; Zhang, Zhi-Ming; Lu, Tong-Bu. Category: iodides-buliding-blocksThis research focused onvisible light absorbing cuprous sensitizer photocatalyst; copper; light harvesting; oxidation; photocatalysis; photosensitizers. The article conveys some information:

Developing strong visible-light-absorbing (SVLA) earth-abundant photosensitizers (PSs) for significantly improving the utilization of solar energy is highly desirable, yet it remains a great challenge. Herein, we adopt a through-bond energy transfer (TBET) strategy by bridging boron dipyrromethene (Bodipy) and a CuI complex with an electronically conjugated bridge, resulting in the first SVLA CuI PSs (Cu-2 and Cu-3). Cu-3 has an extremely high molar extinction coefficient of 162 260 M-1 cm-1 at 518 nm, over 62 times higher than that of traditional CuI PS (Cu-1). The photooxidation activity of Cu-3 is much greater than that of Cu-1 and noble-metal PSs (Ru(bpy)32+ and Ir(ppy)3+) for both energy- and electron-transfer reactions. Femto- and nanosecond transient absorption and theor. investigations demonstrate that a “”ping-pong”” energy-transfer process in Cu-3 involving a forward singlet TBET from Bodipy to the CuI complex and a backward triplet-triplet energy transfer greatly contribute to the long-lived and Bodipy-localized triplet excited state. The results came from multiple reactions, including the reaction of 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Category: iodides-buliding-blocks)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com