Month: October 2022

Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine.The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. COA of Formula: C5H4IN.

Pisacic, Mateja;Biljan, Ivana;Kodrin, Ivan;Popov, Nina;Soldin, Zeljka;Djakovic, Marijana research published 《 Elucidating the Origins of a Range of Diverse Flexible Responses in Crystalline Coordination Polymers》, the research content is summarized as follows. The mech. adaptability of a family of six 1-dimensional crystalline coordination polymers (CPs) of Cd ([CdX₂(3-X’py)₂]_n; 1: X = Br, X’ = Cl, 2: X = I, X’ = Cl, 3: X = I, X’ = Br, 4: X = Cl, X’ = I, 5: X = Br, X’ = I, and 6: X, X’ = I) to applied external force was examined, and a plethora of flexible responses was noticed. While two of the six CPs (4, 6) were slightly elastic, the remaining four CPs (1–3 and 5) presented variable plastic deformation; three of these (1–3) displayed exceptional crystal flow, and one (2) demonstrated unprecedented ductility of crystalline metal-organic material. The feature was examined by theory and custom-designed experiments, and specific and directional intermol. interactions are not only the most influential structural feature in determining the type of mech. responses (i.e., elastic vs. plastic), with interlocking of adjacent mols. playing only a supportive role, but also an unavoidable tool for dialing-in a diversity of plastic responses in Cd(II) coordination polymers.

1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., COA of Formula: C5H4IN

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 144-48-9, formula is C2H4INO, Name is 2-Iodoacetamide.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. Category: iodides-buliding-blocks.

Pinto, Gabriella;Illiano, Anna;Ferrucci, Veronica;Quarantelli, Fabrizio;Fontanarosa, Carolina;Siciliano, Roberto;Di Domenico, Carmela;Izzo, Barbara;Pucci, Piero;Marino, Gennaro;Zollo, Massimo;Amoresano, Angela research published 《 Identification of SARS-CoV-2 Proteins from Nasopharyngeal Swabs Probed by Multiple Reaction Monitoring Tandem Mass Spectrometry》, the research content is summarized as follows. Numerous reverse transcription polymerase chain reaction (RT-PCR) tests have emerged over the past year as the gold standard for detecting millions of cases of SARS-CoV-2 reported daily worldwide. However, problems with critical shortages of key reagents such as PCR primers and RNA extraction kits and unpredictable test reliability related to high viral replication cycles have triggered the need for alternative methodologies to PCR to detect specific COVID-19 proteins. Several authors have developed methods based on liquid chromatog. with tandem mass spectrometry (LC-MS/MS) to confirm the potential of the technique to detect two major proteins, the spike and the nucleoprotein, of COVID-19. In the present work, an S-Trap mini spin column digestion protocol was used for sample preparation prodromal to LC-MS/MS anal. in multiple reactions monitoring ion mode (MRM) to obtain a comprehensive method capable of detecting different viral proteins. The developed method was applied to n. 81 oro/nasopharyngeal swabs submitted in parallel to quant. reverse transcription PCR (RT-qPCR) assays to detect RdRP, the S and N genes specific for COVID-19, and the E gene for all Sarbecoviruses, including SARS-CoV-2 (with cycle negativity threshold set to 40). A total of 23 peptides representative of the six specific viral proteins were detected in the monitoring of 128 transitions found to have good ionic currents extracted in clin. samples that reacted differently to the PCR assay. The best instrumental response came from the FLPFQFGR sequence of spike [558-566] peptide used to test the anal. performance of the method that has good sensitivity with a low false-neg. rate. Transition monitoring using a targeted MS approach has the great potential to detect the fragmentation reactions of any peptide molecularly defined by a specific amino acid sequence, offering the extensibility of the approach to any viral sequence including derived variants and thus providing insights into the development of new types of clin. diagnostics.

Category: iodides-buliding-blocks, 2-Iodoacetamide is a synthetic retinoid that binds to the DNA of cells, altering transcription. It also has been found to be effective in treating bowel disease and has been shown to have dna binding activity. The compound was synthesized by attaching iodine molecules to acetamide. 2-Iodoacetamide targets the protein thiols on the surface of cells, which are responsible for oxidation and damage due to reactive oxygen species (ROS). This compound is metabolized by alcohol dehydrogenase and can be used as a biological sample or natural compound is a compound used as an electrophile for covalent modification of nucleophilic residues on proteins (cysteine, methionine, histidine). When modifying the active-site residues of cysteine proteases, α-Iodoacetamide acts as an irreversible inhibitor of these enzymes.

2-Iodoacetamide used in peptide mapping because it covalently binds with thiols in cysteine residues, thereby preventing disulfide bond formation. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. Also reacts with histidine residues though much more slowly, and this activity is responsible for inhibition of ribonuclease.
An alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate., 144-48-9.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. 626-01-7, formula is C6H6IN, Name is 3-Iodoaniline.The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Name: 3-Iodoaniline.

Pflegr, Vaclav;Horvath, Lilla;Stolarikova, Jirina;Pal, Adrian;Kordulakova, Jana;Bosze, Szilvia;Vinsova, Jarmila;Kratky, Martin research published 《 Design and synthesis of 2-(2-isonicotinoylhydrazineylidene)propanamides as InhA inhibitors with high antitubercular activity》, the research content is summarized as follows. Based on successful antitubercular isoniazid scaffold we have designed its “mee-too” analogs by a combination of this drug linked with substituted anilines through pyruvic acid as a bridge. Lipophilicity important for passive diffusion through impenetrable mycobacterial cell wall was increased by halogen substitution on the aniline. We prepared twenty new 2-(2-isonicotinoylhydrazineylidene)propanamides that were assayed against susceptible Mycobacterium tuberculosis H₃₇Rv, nontuberculous mycobacteria, and also multidrug-resistant tuberculous strains (MDR-TB). All the compounds showed excellent activity not only against Mtb. (min. inhibitory concentrations, MIC, from ≤0.03μM), but also against M. kansasii (MIC ≥2μM). The most active mols. have CF₃ and OCF₃ substituent in the position 4 on the aniline ring. MIC against MDR-TB were from 8μM. The most effective derivatives were used for the mechanism of action investigation. The treatment of Mtb. H₃₇Ra with tested compounds led to decreased production of mycolic acids and the strains overproducing InhA were more resistant to them. These results confirm that studied compounds inhibit the enoyl-acyl carrier protein reductase (InhA) in mycobacteria. The compounds did not show any cytotoxic and cytostatic activity for HepG2 cells. The amides can be considered as a promising scaffold for antitubercular drug discovery having better antimicrobial properties than original isoniazid together with a significantly improved pharmaco-toxicol. profile.

626-01-7, 3-Iodoaniline is a useful research compound. Its molecular formula is C6H6IN and its molecular weight is 219.02 g/mol. The purity is usually 95%.

3-Iodoaniline is a fatty acid that is used in analytical methods to measure the concentration of human serum in blood. It can be used to estimate the population growth rate, with a half-life of about 13 hours. 3-Iodoaniline reacts with hydrogen bond and proton to form a reaction solution, which can be catalyzed by palladium-catalyzed coupling and suzuki coupling reactions. The activation energies for these reactions are typically in the range of 4-8 kcal/mol. The chemical ionization technique is a type of mass spectrometry that is used to determine kinetic data for this compound. Hydrochloric acid can be added as an acid catalyst to increase the rate of reaction and generate more accurate kinetic data., Name: 3-Iodoaniline

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 144-48-9, formula is C2H4INO, Name is 2-Iodoacetamide.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. Synthetic Route of 144-48-9.

Peng, Zhihong;Nguyen, Trung T.;Song, Wei;Anderson, Bowen;Wolter, William R.;Schroeder, Valerie A.;Hesek, Dusan;Lee, Mijoon;Mobashery, Shahriar;Chang, Mayland research published 《 Selective MMP-9 Inhibitor (R)-ND-336 Alone or in Combination with Linezolid Accelerates Wound Healing in Infected Diabetic Mice》, the research content is summarized as follows. Diabetic foot ulcers (DFUs) are a common complication of diabetes that are recalcitrant to healing due to persistent inflammation. The majority of DFUs have bacterial biofilms, with Staphylococcus epidermidis as a predominant bacterium, requiring infection control with antibiotics before treatment of the wound. Matrix metalloproteinases (MMPs) play roles in the pathol. and repair of DFUs. However, defining the roles of the 24 human MMPs has been challenging due to the presence of three forms for each MMP, of which only one is catalytically competent, and the lack of convenient methods to distinguish among the three forms of MMPs. Using an affinity resin that binds only to the active forms of MMPs, with identification and quantification by mass spectrometry, we found that infected wounds in mice had increased levels of active MMP-9 compared to uninfected ones, paralleling infected human DFUs. MMP-9 activity prevents diabetic wounds from healing. We evaluated the efficacy of the selective small-mol. MMP-9 inhibitor, (R)-ND-336, in the infected diabetic mouse model of wound healing and showed that (R)-ND-336 alone or in combination with the antibiotic linezolid improves wound healing by inhibiting the detrimental MMP-9, mitigating macrophage infiltration to diminish inflammation, and increasing angiogenesis to restore the normal wound healing process. An advantage of this strategy is the ability to administer (R)-ND-336 concurrently with an antibiotic.

144-48-9, 2-Iodoacetamide is a synthetic retinoid that binds to the DNA of cells, altering transcription. It also has been found to be effective in treating bowel disease and has been shown to have dna binding activity. The compound was synthesized by attaching iodine molecules to acetamide. 2-Iodoacetamide targets the protein thiols on the surface of cells, which are responsible for oxidation and damage due to reactive oxygen species (ROS). This compound is metabolized by alcohol dehydrogenase and can be used as a biological sample or natural compound is a compound used as an electrophile for covalent modification of nucleophilic residues on proteins (cysteine, methionine, histidine). When modifying the active-site residues of cysteine proteases, α-Iodoacetamide acts as an irreversible inhibitor of these enzymes.

2-Iodoacetamide used in peptide mapping because it covalently binds with thiols in cysteine residues, thereby preventing disulfide bond formation. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. Also reacts with histidine residues though much more slowly, and this activity is responsible for inhibition of ribonuclease.
An alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate., Synthetic Route of 144-48-9

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine.Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Reference of 5029-67-4.

Peng, Dao;Zhang, Yu;Liu, Xiao-Qing;Shang, Hang;Lin, Gang;Jin, Hong-Ying;Liu, Xue-Fen;He, Ran;Shang, Ye-Han;Xu, Yin-Hua;Luo, Shu-Ping research published 《 Highly active and reusable copper phthalocyanine derivatives catalyzed the hydroxylation of (hetero)aryl halides》, the research content is summarized as follows. Authors have researched and developed a series of copper phthalocyanine derivatives as new highly active and reusable catalysts for the hydroxylation of (hetero)aryl halides. The perfluorinated copper phthalocyanine (CuPcF16) showed the highest activity for the hydroxylation of aryl iodide with an excellent yield (up to 98%) under low catalytic loading (0.5 mol% CuPcF₁₆). Similarly, the hydroxylation of aryl bromides and aryl chlorides catalyzed by CuPcF₁₆ also had high activity with 42-98% yield. Moreover, the recyclability of this catalyst can up to 6 times without significant loss in catalytic activity.

5029-67-4, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., Reference of 5029-67-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine.The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Safety of 3-Iodopyridine.

Peng, Dao;Zhang, Yu;Liu, Xiao-Qing;Shang, Hang;Lin, Gang;Jin, Hong-Ying;Liu, Xue-Fen;He, Ran;Shang, Ye-Han;Xu, Yin-Hua;Luo, Shu-Ping research published 《 Highly active and reusable copper phthalocyanine derivatives catalyzed the hydroxylation of (hetero)aryl halides》, the research content is summarized as follows. Authors have researched and developed a series of copper phthalocyanine derivatives as new highly active and reusable catalysts for the hydroxylation of (hetero)aryl halides. The perfluorinated copper phthalocyanine (CuPcF16) showed the highest activity for the hydroxylation of aryl iodide with an excellent yield (up to 98%) under low catalytic loading (0.5 mol% CuPcF₁₆). Similarly, the hydroxylation of aryl bromides and aryl chlorides catalyzed by CuPcF₁₆ also had high activity with 42-98% yield. Moreover, the recyclability of this catalyst can up to 6 times without significant loss in catalytic activity.

1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., Safety of 3-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine.Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Application In Synthesis of 5029-67-4.

Paul, Sudeep;Joy, Bony P.;Sasikala, Geethu;Raghuthaman, Advaya G.;Gudimetla, Vittal B. research published 《 Copper-NHC Based Ullmann Catalysis In Water For Selective N-Arylation Of 3-Aminophenols》, the research content is summarized as follows. This work elucidated synthesis of diarylamines RNHR¹ [R = 3-OH, 2-Me-3-OH, 4-Me-3-OH; R¹ = Ph, 4-OMe, pyridin-2-yl, etc.] via chemoselective N-arylation of 3-aminophenols and aryl iodides using 1,3-bis-[2-hydroxyphenyl] imidazolium chloride (IHPHCl) and copper iodide as catalyst (1 mol %) in aqueous medium. Presence of chelating group (-OH) on IHPHCl enhanced N-selectivity. Overall this was a simple and green method for selective N-arylation of 3-aminophenols with good substrate scope and yields (60-88%).

5029-67-4, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., Application In Synthesis of 5029-67-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. Name: 3-Iodopyridine.

Paul, Sudeep;Joy, Bony P.;Sasikala, Geethu;Raghuthaman, Advaya G.;Gudimetla, Vittal B. research published 《 Copper-NHC Based Ullmann Catalysis In Water For Selective N-Arylation Of 3-Aminophenols》, the research content is summarized as follows. This work elucidated synthesis of diarylamines RNHR¹ [R = 3-OH, 2-Me-3-OH, 4-Me-3-OH; R¹ = Ph, 4-OMe, pyridin-2-yl, etc.] via chemoselective N-arylation of 3-aminophenols and aryl iodides using 1,3-bis-[2-hydroxyphenyl] imidazolium chloride (IHPHCl) and copper iodide as catalyst (1 mol %) in aqueous medium. Presence of chelating group (-OH) on IHPHCl enhanced N-selectivity. Overall this was a simple and green method for selective N-arylation of 3-aminophenols with good substrate scope and yields (60-88%).

Name: 3-Iodopyridine, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. 626-01-7, formula is C6H6IN, Name is 3-Iodoaniline. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. SDS of cas: 626-01-7.

Pathak, Pratima;Sarycheva, Anastasia;Baird, Matthew A.;Shvartsburg, Alexandre A. research published 《 Delineation of Isomers by the ¹³C Shifts in Ion Mobility Spectra》, the research content is summarized as follows. Mass spectrometry (MS) and isotopes were intertwined for a century, with stable isotopes central to many MS identification and quantification protocols. In contrast, the anal. separations including ion mobility spectrometry (IMS) largely ignored isotopes, partly because of insufficient resolution We recently delineated various halogenated aniline isomers by structurally specific splitting in FAIMS spectra. While this capability hinges on the ¹³C shifts, all preceding studies leveraged ³⁷Cl or ⁸¹Br to enhance the differentiation. However, such abundant heavy isotopes are absent from typical organic compounds With single I isotope, iodinated organics generate similar isotopic envelopes dominated by the ¹³C atoms. Here, we distinguish the three monoiodoaniline isomers based on the shifts solely for one or two ¹³C atoms. The differentiation may be somewhat improved using multipoint peak position descriptions for more reproducible shifts. The interisomer order of shifts differs from those for chlorinated or brominated analogs, showcasing the specificity of approach. We also investigated the mass scaling of isotopic shifts, encountering divergent trends for different structural families.

SDS of cas: 626-01-7, 3-Iodoaniline is a useful research compound. Its molecular formula is C6H6IN and its molecular weight is 219.02 g/mol. The purity is usually 95%.

3-Iodoaniline is a fatty acid that is used in analytical methods to measure the concentration of human serum in blood. It can be used to estimate the population growth rate, with a half-life of about 13 hours. 3-Iodoaniline reacts with hydrogen bond and proton to form a reaction solution, which can be catalyzed by palladium-catalyzed coupling and suzuki coupling reactions. The activation energies for these reactions are typically in the range of 4-8 kcal/mol. The chemical ionization technique is a type of mass spectrometry that is used to determine kinetic data for this compound. Hydrochloric acid can be added as an acid catalyst to increase the rate of reaction and generate more accurate kinetic data., 626-01-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. Category: iodides-buliding-blocks.

Park, Byoung Yong;Lim, Taeho;Han, Min Su research published 《 A simple and efficient in situ generated copper nanocatalyst for stereoselective semihydrogenation of alkynes》, the research content is summarized as follows. (Z)-selective semihydrogenation of alkynes were achieved using a copper nanocatalyst which was generated in situ by adding ammonia borane to an ethanol solution of copper sulfate. Different types of alkynes including aryl-aryl, aryl-alkyl, and aliphatic alkynes were selectively reduced to (Z)-alkenes affording up to 99% isolated yield. The semihydrogenation of terminal alkynes to alkenes and gram-scale applications were also reported. In addition to eliminating catalyst preparation, the proposed approach were simple and practical and served as a suitable alternative method to the conventional Lindlar catalyst.

Category: iodides-buliding-blocks, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com