Month: October 2022

In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. Recommanded Product: 2-Iodopyridine.

Miller, Eric M.;Walczak, Maciej A. research published 《 Light-Mediated Cross-Coupling of Anomeric Trifluoroborates》, the research content is summarized as follows. Stereoselective reactions at the anomeric carbon constitute the cornerstone of preparative carbohydrate chem. Here, we report stereoselective C-arylation and etherification reactions of anomeric trifluoroborates derived from BMIDA esters. These reactions are characterized by high anomeric selectivities for 2-deoxysugars and broad substrate scope (24 examples), including disaccharides and trifluoroborates with free hydroxyl groups. Taken together, this new class of carbohydrate reagents adds the palette of anomeric nucleophile reagents suitable for efficient installation of C-C bonds.

Recommanded Product: 2-Iodopyridine, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., 5029-67-4.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons-Smith reaction (cyclopropanation using iodomethane), 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine. Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction. Computed Properties of 1120-90-7.

Milic, Mira;Targos, Karina;Tellez Chavez, Magda;Thompson, Madison A. M.;Jennings, Julia J.;Franz, Annaliese K. research published 《 NMR Quantification of Hydrogen-Bond-Accepting Ability for Organic Molecules》, the research content is summarized as follows. The hydrogen-bond-accepting abilities for more than 100 organic mols. are quantified using ¹⁹F and ³¹P NMR spectroscopy with pentafluorobenzoic acid (PFBA) and phenylphosphinic acid (PPA) as com. available, inexpensive probes. Anal. of pyridines and anilines with a variety of electronic modifications demonstrates that changes in NMR shifts can predict the secondary effects that contribute to H-bond-accepting ability, establishing the ability of PFBA and PPA binding to predict electronic trends. The H-bond-accepting abilities of various metal-chelating ligands and organocatalysts are also quantified. The measured Δδ(³¹P) and Δδ_p(¹⁹F) values correlate strongly with Hammett parameters, pK_a of the protonated HBA, and proton-transfer basicity (pK_BH+).

Computed Properties of 1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., 1120-90-7.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 626-01-7, formula is C6H6IN, Name is 3-Iodoaniline.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. Recommanded Product: 3-Iodoaniline.

Michalke, Jessica;Haas, Michael;Krisch, Dominik;Boegl, Thomas;Bartling, Stephan;Rockstroh, Nils;Schoefberger, Wolfgang;Topf, Christoph research published 《 Generation of Cobalt-Containing Nanoparticles on Carbon via Pyrolysis of a Cobalt Corrole and Its Application in the Hydrogenation of Nitroarenes》, the research content is summarized as follows. The manufacture of a state-of-the-art heterogeneous non-noble metal catalyst was reported, which was based on a molecularly well-defined phosphine-tagged cobalt corrole complex. This precursor compound was readily synthesized from convenient starting materials while the active material is obtained through wet-impregnation of the pertinent metalliferous macrocycle onto carbon black followed by controlled pyrolysis of the loaded carrier material under an inert gas atm. Thus, the obtained composite was then applied in the heterogeneous hydrogenation of various nitroarenes to yield a vast array of valuable aniline derivatives that were conveniently isolated as their hydrochloride salts. The introduced catalytic protocol was robust and user-friendly with the entire assembly of the reaction set-up enabling the conduction of the experiments on the laboratory bench without any protection from air.

626-01-7, 3-Iodoaniline is a useful research compound. Its molecular formula is C6H6IN and its molecular weight is 219.02 g/mol. The purity is usually 95%.

3-Iodoaniline is a fatty acid that is used in analytical methods to measure the concentration of human serum in blood. It can be used to estimate the population growth rate, with a half-life of about 13 hours. 3-Iodoaniline reacts with hydrogen bond and proton to form a reaction solution, which can be catalyzed by palladium-catalyzed coupling and suzuki coupling reactions. The activation energies for these reactions are typically in the range of 4-8 kcal/mol. The chemical ionization technique is a type of mass spectrometry that is used to determine kinetic data for this compound. Hydrochloric acid can be added as an acid catalyst to increase the rate of reaction and generate more accurate kinetic data., Recommanded Product: 3-Iodoaniline

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In everyday life, iodide is most commonly encountered as a component of iodized salt, which many governments mandate. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine. Worldwide, iodine deficiency affects two billion people and is the leading preventable cause of intellectual disability. Recommanded Product: 2-Iodopyridine.

Mhaldar, Pradeep M.;Patil, Mayuri V.;Rashinkar, Gajanan S.;Pore, Dattaprasad M. research published 《 Magnetically Recoverable Palladium Nanocatalyst [Pd(II)-Benz-Am-Fe₃O₄@SiO₂] for Ullmann Type Homocoupling of Aryl halides with N₂H₄ as an Efficient Reductant》, the research content is summarized as follows. A highly efficient and sustainable ferrite supported palladium nanocatalyst (Pd(II)-Benz-Am-Fe₃O₄@SiO₂) has been prepared and characterized by diverse microscopic and spectroscopic techniques. The Pd(II)-Benz-Am-Fe₃O₄@SiO₂ was employed as magnetically recoverable nanocatalyst in the synthesis of sym. biaryls by reductive homocoupling of haloarenes (I, Br and Cl) using hydrazine hydrate (N₂H₄) as reducing agent. The Pd-Benz-Am-Fe₃O₄@SiO₂ nanocatalyst exhibited high surface area and efficient magnetization as 45.25 m²/g and 34 emu/g, resp. The Electron Dispersive X-ray (EDX) anal. confirmed 3.9 mol % loading of Pd in Pd-Benz-Am-Fe₃O₄@SiO₂. Moverever, high turnover number (TON) and turnover frequency (TOF), operational simplicity and facial recyclability and reusability (up to eight runs) are the remarkable advantages of the nanocatalyst. The catalytic activity and stability of recycled Pd(II)-Benz-Am-Fe₃O₄@SiO₂ catalyst was comprehensively studied from X-ray diffraction (XRD), SEM (SEM), Transmission Electron Microscopic (TEM) and EDX anal.

Recommanded Product: 2-Iodopyridine, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., 5029-67-4.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. 144-48-9, formula is C2H4INO, Name is 2-Iodoacetamide.Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. COA of Formula: C2H4INO.

Mezger, Stephanie T. P.;Mingels, Alma M. A.;Bekers, Otto;Heeren, Ron M. A.;Cillero-Pastor, Berta research published 《 Mass Spectrometry Spatial-Omics on a Single Conductive Slide》, the research content is summarized as follows. Mass spectrometry imaging (MSI) can analyze the spatial distribution of hundreds of different mols. directly from tissue sections usually placed on conductive glass slides to provide conductivity on the sample surface. Addnl. experiments are often required for mol. identification using consecutive sections on membrane slides compatible with laser capture microdissection (LMD). In this work, we demonstrate for the first time the use of a single conductive slide for both matrix-assisted laser desorption ionization (MALDI)-MSI and direct proteomics. In this workflow, regions of interest can be directly ablated with LMD while preserving protein integrity. These results offer an alternative for MSI-based multimodal spatial-omics.

144-48-9, 2-Iodoacetamide is a synthetic retinoid that binds to the DNA of cells, altering transcription. It also has been found to be effective in treating bowel disease and has been shown to have dna binding activity. The compound was synthesized by attaching iodine molecules to acetamide. 2-Iodoacetamide targets the protein thiols on the surface of cells, which are responsible for oxidation and damage due to reactive oxygen species (ROS). This compound is metabolized by alcohol dehydrogenase and can be used as a biological sample or natural compound is a compound used as an electrophile for covalent modification of nucleophilic residues on proteins (cysteine, methionine, histidine). When modifying the active-site residues of cysteine proteases, α-Iodoacetamide acts as an irreversible inhibitor of these enzymes.

2-Iodoacetamide used in peptide mapping because it covalently binds with thiols in cysteine residues, thereby preventing disulfide bond formation. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. Also reacts with histidine residues though much more slowly, and this activity is responsible for inhibition of ribonuclease.
An alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate., COA of Formula: C2H4INO

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine.Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. HPLC of Formula: 5029-67-4.

Meng, Qi;Zhang, Lian;Zhu, Xinhui;Teng, Qiaoqiao research published 《 Synthesis of 9-O-Arylated Berberine with a Polystyrene Resin Supported Copper(II) Catalyst》, the research content is summarized as follows. A series of polyfluorobenzene, pyridine and aniline substituted berberine derivatives I (Ar = Ph, 4-H₂NC₆H₄, 3-pyridyl, etc.) were prepared via resin-supported Cu(II) catalyzed cross-coupling reactions of tetrahydroberberrubine with iodoarenes and subsequent I₂ oxidation The best catalyst, a polyethyleneimine functionalized polystyrene supported Cu²⁺ (PSAPA·Cu(II)), could be reused for at least 5 runs without significant loss of catalytic activity. Comparative studies on the morphol. and porous structures of the materials suggested a catalyst with a moderate sp. surface area and larger pore diameters was more active in catalyzing the cross-coupling reactions.

5029-67-4, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., HPLC of Formula: 5029-67-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In general, organic iodides are light-sensitive and turn yellow during storage, owing to the formation of iodine. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine.Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles. Application In Synthesis of 1120-90-7.

Meng, Qi;Zhang, Lian;Zhu, Xinhui;Teng, Qiaoqiao research published 《 Synthesis of 9-O-Arylated Berberine with a Polystyrene Resin Supported Copper(II) Catalyst》, the research content is summarized as follows. A series of polyfluorobenzene, pyridine and aniline substituted berberine derivatives I (Ar = Ph, 4-H₂NC₆H₄, 3-pyridyl, etc.) were prepared via resin-supported Cu(II) catalyzed cross-coupling reactions of tetrahydroberberrubine with iodoarenes and subsequent I₂ oxidation The best catalyst, a polyethyleneimine functionalized polystyrene supported Cu²⁺ (PSAPA·Cu(II)), could be reused for at least 5 runs without significant loss of catalytic activity. Comparative studies on the morphol. and porous structures of the materials suggested a catalyst with a moderate sp. surface area and larger pore diameters was more active in catalyzing the cross-coupling reactions.

1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., Application In Synthesis of 1120-90-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 144-48-9, formula is C2H4INO, Name is 2-Iodoacetamide.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. SDS of cas: 144-48-9.

Menfaatli, Esra;Zihnioglu, Figen research published 《 Egg white protein polymer: an affinity matrix for protease enrichment and isolation》, the research content is summarized as follows. Egg white was precipitated with acetone and crosslinked with glutaraldehyde. Protease specificity of the polymer was investigated with different types of proteases and non-protease proteins. Protein polymer effectively bound trypsin, papain and the different proteases from pancreatin. SDS-PAGE results and diffusion agar plate tests supported the protease-binding efficiency of the polymer. In conclusion, egg white protein polymer can specifically bind proteases and it is a convenient and cost-effective material for enrichment, isolation, and removal of proteases.

SDS of cas: 144-48-9, 2-Iodoacetamide is a synthetic retinoid that binds to the DNA of cells, altering transcription. It also has been found to be effective in treating bowel disease and has been shown to have dna binding activity. The compound was synthesized by attaching iodine molecules to acetamide. 2-Iodoacetamide targets the protein thiols on the surface of cells, which are responsible for oxidation and damage due to reactive oxygen species (ROS). This compound is metabolized by alcohol dehydrogenase and can be used as a biological sample or natural compound is a compound used as an electrophile for covalent modification of nucleophilic residues on proteins (cysteine, methionine, histidine). When modifying the active-site residues of cysteine proteases, α-Iodoacetamide acts as an irreversible inhibitor of these enzymes.

2-Iodoacetamide used in peptide mapping because it covalently binds with thiols in cysteine residues, thereby preventing disulfide bond formation. By virtue of reaction with cysteine, it is an irreversible inhibitor of enzymes with cysteine at the active site. Also reacts with histidine residues though much more slowly, and this activity is responsible for inhibition of ribonuclease.
An alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate., 144-48-9.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. 5029-67-4, formula is C5H4IN, Name is 2-Iodopyridine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Related Products of 5029-67-4.

Mcnamee, Ryan E.;Haugland, Marius M.;Nugent, Jeremy;Chan, Rachel;Christensen, Kirsten E.;Anderson, Edward A. research published 《 Synthesis of 1,3-disubstituted bicyclo[1.1.0]butanes via directed bridgehead functionalization》, the research content is summarized as follows. Bicyclo[1.1.0]butanes (BCBs) are increasingly valued as intermediates in ‘strain release’ chem. for the synthesis of substituted four membered rings and bicyclo[1.1.1]pentanes, with applications including bioconjugation processes. Variation of the BCB bridgehead substituents can be challenging due to the inherent strain of the bicyclic scaffold, often necessitating linear syntheses of specific BCB targets. Here authors report the first palladium catalyzed cross-coupling on pre-formed BCBs which enables a ‘late stage’ diversification of the bridgehead position, and the conversion of the resultant products into a range of useful small ring building blocks.

5029-67-4, 2-Iodopyridine can be synthesized from 2-chloropyridine or 2-bromopyridine via treatment with iodotrimethylsilane.
2-Iodopyridine, also known as 2-Iodopyridine, is a useful research compound. Its molecular formula is C5H4IN and its molecular weight is 205 g/mol. The purity is usually 95%.
2-Iodopyridine is a halogenated building block. It is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
2-Iodopyridine is a white crystalline solid that is soluble in water, alcohol, and ether. The molecule contains a methyl group and two iodine atoms. 2-Iodopyridine has several industrial uses. It acts as a precursor to various pharmaceuticals and agrochemicals. The compound also exhibits insulin resistance properties, which may be related to its ability to bind to the insulin receptor and inhibit insulin signaling. 2-Iodopyridine can also be used for treating cancer because it binds to the DNA of cancer cells, preventing replication and leading to cell death.
2-Iodopyridine is a reagent used in the preparation of human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors., Related Products of 5029-67-4

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Iodide is one of the largest monatomic anions. It is assigned a radius of around 206 picometers. 1120-90-7, formula is C5H4IN, Name is 3-Iodopyridine.For comparison, the lighter halides are considerably smaller: bromide (196 pm), chloride (181 pm), and fluoride (133 pm). In part because of its size, iodide forms relatively weak bonds with most elements. Recommanded Product: 3-Iodopyridine.

Mcnamee, Ryan E.;Haugland, Marius M.;Nugent, Jeremy;Chan, Rachel;Christensen, Kirsten E.;Anderson, Edward A. research published 《 Synthesis of 1,3-disubstituted bicyclo[1.1.0]butanes via directed bridgehead functionalization》, the research content is summarized as follows. Bicyclo[1.1.0]butanes (BCBs) are increasingly valued as intermediates in ‘strain release’ chem. for the synthesis of substituted four membered rings and bicyclo[1.1.1]pentanes, with applications including bioconjugation processes. Variation of the BCB bridgehead substituents can be challenging due to the inherent strain of the bicyclic scaffold, often necessitating linear syntheses of specific BCB targets. Here authors report the first palladium catalyzed cross-coupling on pre-formed BCBs which enables a ‘late stage’ diversification of the bridgehead position, and the conversion of the resultant products into a range of useful small ring building blocks.

1120-90-7, 3-Iodopyridine is a heteroaryl halide. It undergoes microwave-assisted coupling with heterocyclic compounds (pyrazole, imidazole, pyrrole and indole) to afford the corresponding N-3-pyridinyl-substituted heterocyclic compounds.

3-Iodopyridine is a useful research chemical used as a reactant in the copper-catalyzed coupling of alkylamines and aryl iodides.

3-Iodopyridine is an isomeric compound that can be synthesized by cross-coupling reactions. This compound has been shown to have nicotinic acetylcholine receptor binding properties and may be useful in the treatment of Alzheimer’s disease. 3-Iodopyridine is a primary amino acid that can be used for the synthesis of amines, which are nitrogen nucleophiles. It has been crystallized with halides and its x-ray structures have been determined. The nmr spectra of 3-iodopyridine show that it contains phosphorus and nitrogen atoms. 3-Iodopyridine is also able to take up nitrate ions from solution, which may be due to its uptake properties., Recommanded Product: 3-Iodopyridine

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com