Month: October 2022

The author of 《PdxCuy decorate hypercrosslinked network: Synthesis and application as efficient catalysts for the reduction of 4-nitrophenol and Suzuki-Miyaura coupling reaction》 were Bi, Jiajun; Dong, Yahao; Zhu, Dajian; Guo, Wen; Meng, Di; Li, Tao. And the article was published in Applied Surface Science in 2019. Application In Synthesis of 1-Iodo-4-methylbenzene The author mentioned the following in the article:

4-Nitrophenol may accumulate in the food chain and cause various fatal diseases. Hence, in order to meet the principle of safety, health and environmental protection, achieving high conversion of 4-nitrophenol with efficient and cheaper method is always in demand. In this aspect, a series of five PdxCuy/Ph-Sa-1 (4:0, 3:1, 2:2, 1:3 and 0:4) catalysts were designed and characterized by FT-IR, TEM, SEM, TGA, AAS, XPS and so on. Furthermore, the catalytic performance of several PdxCuy/Ph-Sa-1 were investigated via 4-nitrophenol reduction and kinetics, where Pd2Cu2/Ph-Sa-1 showed higher catalytic activity than Pd/Ph-Sa-1 with the same Pd content. In particular, Pd/Ph-Sa-1 also exhibited excellent catalytic performance in Suzuki-Miyaura coupling reaction. Linking salen-1 monomer and benzene through Scholl reaction was presented as an effective route to obtain polymeric substrate with low-cost and simple synthesis method. In addition, Pd/Ph-Sa-1 showed desirable recyclability with maintaining its catalytic activity even after five recycles, we also studied the morphol. and Pd state of Pd/Ph-Sa-1 after five recycles by TEM and XPS. This work is highly suggestive on the heterogeneous catalysts design and application. In the experiment, the researchers used 1-Iodo-4-methylbenzene(cas: 624-31-7Application In Synthesis of 1-Iodo-4-methylbenzene)

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Application In Synthesis of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Catalytic asymmetric acetalization of carboxylic acids for access to chiral phthalidyl ester prodrugs》 were Liu, Yingguo; Chen, Qiao; Mou, Chengli; Pan, Lutai; Duan, Xiaoyong; Chen, Xingkuan; Chen, Hongzhong; Zhao, Yanli; Lu, Yunpeng; Jin, Zhichao; Chi, Yonggui Robin. And the article was published in Nature Communications in 2019. Product Details of 619-58-9 The author mentioned the following in the article:

Carboxylic acids are common moieties in medicines. They can be converted to phthalidyl esters as prodrugs. Unfortunately, phthalidyl esters are now mostly prepared in racemic forms. This is not desirable because the two enantiomers of phthalidyl esters likely have different pharmacol. effects. Here, the authors address the synthetic challenges in enantioselective modification of carboxylic acids via asym. acetalizations. The key reaction step involves asym. addition of a carboxylic acid to the catalyst-bound intermediate. This addition step enantioselectively constructs a chiral acetal unit that leads to optically enriched phthalidyl esters. A broad range of carboxylic acids react effectively under mild and transition metal-free conditions. Preliminary bioactivity studies show that the two enantiomers of chlorambucil phthalidyl esters exhibit different anti-cancer activities to inhibit the growth of Hela cells. Our catalytic strategy of asym. acetalizations of carboxylic acids shall benefit future development of chiral phthalidyl ester prodrugs and related mols. In addition to this study using 4-Iodobenzoic acid, there are many other studies that have used 4-Iodobenzoic acid(cas: 619-58-9Product Details of 619-58-9) was used in this study.

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Product Details of 619-58-9 Organic iodides can be alkyl, alkenyl, or alkynyl, and all of them are very reactive toward with many kinds of nucleophiles.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Enhancing near-infrared photoluminescence from single-walled carbon nanotubes by defect-engineering using benzoyl peroxide》 was published in Scientific Reports in 2020. These research results belong to Przypis, Lukasz; Krzywiecki, Maciej; Niidome, Yoshiaki; Aoki, Haruka; Shiraki, Tomohiro; Janas, Dawid. Category: iodides-buliding-blocks The article mentions the following:

Single-walled carbon nanotubes (SWCNTs) have been modified with ester groups using typical organic radical chem. Consequently, traps for mobile excitons have been created, which enhanced the optical properties of the material. The proposed methodol. combines the benefits of mainstream approaches to create luminescent defects in SWCNTs while it simultaneously avoids their limitations. A step change was achieved when the aqueous medium was abandoned. The selection of an appropriate organic solvent enabled much more facile modification of SWCNTs. The presented technique is quick and versatile as it can engage numerous reactants to tune the light emission capabilities of SWCNTs. Importantly, it can also utilize SWCNTs sorted by chirality using conjugated polymers to enhance their light emission capabilities. Such differentiation is conducted in organic solvents, so monochiral SWCNT can be directly functionalized using the demonstrated concept in the same medium without the need to redisperse the material in water. In the part of experimental materials, we found many familiar compounds, such as 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Category: iodides-buliding-blocks)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Category: iodides-buliding-blocks

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Methoxy-Functionalized Triarylamine-Based Hole-Transporting Polymers for Highly Efficient and Stable Perovskite Solar Cells》 was written by Kim, Youngwoong; Kim, Geunjin; Jeon, Nam Joong; Lim, Chulhee; Seo, Jangwon; Kim, Bumjoon J.. Product Details of 589-87-7 And the article was included in ACS Energy Letters in 2020. The article conveys some information:

The hole-transporting layer is an essential component in a perovskite solar cell (PSC) and plays a key role in controlling both power conversion efficiency (PCE) and stability. Here, a new hole-transporting material (HTM), methoxy group-containing poly(triarylamine) (PTAA) (CH3O-PTAA) is reported for efficient PSCs with improved thermal stability. As compared to commonly used PTAA (CH3-PTAA), CH3O-PTAA exhibits enhanced doping ability and stability under thermal stress. With CH3O-PTAA, (FAPbI3)0.85(MAPbBr3)0.15-based PSCs show high PCEs > 20%, comparable to those of CH3-PTAA devices. More importantly, better long-term thermal stability with only 3% reduction from the initial PCE (6.1% reduction on average) has been achieved for encapsulated PSCs with CH3O-PTAA than that of PSCs with CH3-PTAA under dark storage conditions (ISOS-D-3) of 85° and 85% relative humidity (RH) over 1000 h. Detailed studies have been conducted to reveal the strong correlation between the doping behavior of HTMs and the performance of PSCs, which provide useful guidelines for the design of new HTMs for efficient and stable PSCs. In the experimental materials used by the author, we found 1-Bromo-4-iodobenzene(cas: 589-87-7Product Details of 589-87-7)

1-Bromo-4-iodobenzene(cas: 589-87-7) is mainly used as the OLED pharmaceutical intermediate, as reagent for in situ desilylation and coupling of silylated alkynes, as substrate in copper-free Sonogashira coupling in aqueous acetone..Product Details of 589-87-7 It is also used in synthesis of β,β,dibromostyrenes, as starting reagent in the total syntheses of ent-conduramine A and ent-7-deoxypancratistatin (alkaloids)

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《In situ decorated Pd NPs on chitosan-encapsulated Fe3O4/SiO2-NH2 as magnetic catalyst in Suzuki-Miyaura coupling and 4-nitrophenol reduction》 was written by Veisi, Hojat; Ozturk, Turan; Karmakar, Bikash; Tamoradi, Taiebeh; Hemmati, Saba. Quality Control of 1-Iodo-4-methylbenzene And the article was included in Carbohydrate Polymers in 2020. The article conveys some information:

Chitosan is a linear polysaccharide and non-toxic bioactive polymer with a wide variety of applications due to its functional properties such as ease of modification, and biodegradability. In this study, a green protocol for in situ fabrication of ultrafine Pd nanoparticles on chitosan-encapsulated Fe3O4/SiO2-NH2 nanoparticles, without the use of any toxic reducing agents, is described. The catalytic activity of Fe3O4/SiO2-NH2@CS/Pd nanocomposite was investigated through Suzuki-Miyaura coupling to synthesize biaryl derivatives, and reduction of 4-nitrophenol to 4-aminophenol. The core-shell nanoparticle modified with chitosan highly stabilizes the exterior Pd NPs. Leaching test was performed to assure heterogeneity of the catalyst. The magnetically retrievable catalyst was recycled up to eight times in both reactions without significant loss in its activity. In addition to this study using 1-Iodo-4-methylbenzene, there are many other studies that have used 1-Iodo-4-methylbenzene(cas: 624-31-7Quality Control of 1-Iodo-4-methylbenzene) was used in this study.

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Quality Control of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Tripathy, Alisha Rani; Yedase, Girish Suresh; Yatham, Veera Reddy published their research in RSC Advances in 2021. The article was titled 《Cerium photocatalyzed radical Smiles rearrangement of 2-aryloxybenzoic acids》.Application of 626-02-8 The article contains the following contents:

A cerium photocatalyzed aryl migration from an aryl ether to a carboxylic acid group through radical-Smiles rearrangement was reported. This operationally simple protocol utilized inexpensive CeCl3 as a photocatalyst and converted a variety of 2-aryloxybenzoic acids into aryl-2-hydroxybenzoates in good yields. The experimental process involved the reaction of 3-Iodophenol(cas: 626-02-8Application of 626-02-8)

3-Iodophenol(cas: 626-02-8) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Application of 626-02-8Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chen, Kun-Quan; Shen, Jie; Wang, Zhi-Xiang; Chen, Xiang-Yu published their research in Chemical Science in 2021. The article was titled 《A donor-acceptor complex enables the synthesis of E-olefins from alcohols, amines and carboxylic acids》.Computed Properties of C10H18INO2 The article contains the following contents:

Herein, a fundamentally distinct strategy enabled by electron donor-acceptor (EDA) complexes was presented for the selective synthesis of olefins from simple and easily available starting materials such as alcs., amines and carboxylic acids. The conversions took place via photoactivation of the EDA complexes of the activated substrates with alkali salts, followed by hydrogen atom elimination from in-situ generated alkyl radicals. This method was operationally simple and straightforward and free of photocatalysts and transition-metals, and showed high regio- and stereoselectivities. In the part of experimental materials, we found many familiar compounds, such as tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3Computed Properties of C10H18INO2)

tert-Butyl 4-iodopiperidine-1-carboxylate(cas: 301673-14-3) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Computed Properties of C10H18INO2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wong, Alice R.; Fastuca, Nicholas J.; Mak, Victor W.; Kerkovius, Jeffrey K.; Stevenson, Susan M.; Reisman, Sarah E. published their research in ACS Central Science in 2021. The article was titled 《Total Syntheses of the C19 Diterpenoid Alkaloids (-)-Talatisamine, (-)-Liljestrandisine, and (-)-Liljestrandinine by a Fragment Coupling Approach》.SDS of cas: 624-73-7 The article contains the following contents:

The C19 diterpenoid alkaloids (C19 DTAs) are a large family of natural products, many of which modulate the activity of ion channels in vivo and are therefore of interest for the study of neurol. and cardiovascular diseases. The complex architectures of these mols. continue to challenge the state-of-the-art in chem. synthesis, particularly with respect to efficient assembly of their polcyclic ring systems. Here, the authors report the total syntheses of (-)-talatisamine (I), (-)-liljestrandisine (II), and (-)-liljestrandinine (III), three aconitine-type C19 DTAs, using a fragment coupling strategy. Key to this approach is a 1,2-addition/semipinacol rearrangement sequence which efficiently joins two complex fragments and sets an all-carbon quaternary center. In the part of experimental materials, we found many familiar compounds, such as 1,2-Diiodoethane(cas: 624-73-7SDS of cas: 624-73-7)

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.SDS of cas: 624-73-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Faltracco, Matteo; Damian, Matteo; Ruijter, Eelco published an article in 2021. The article was titled 《Synthesis of Carbazoles and Dihydrocarbazoles by a Divergent Cascade Reaction of Donor-Acceptor Cyclopropanes》, and you may find the article in Organic Letters.Recommanded Product: Trimethylsulfoxonium iodide The information in the text is summarized as follows:

An alkylation/olefination cascade of indolecarboxaldehydes and phosphonate-functionalized donor-acceptor cyclopropanes affords functionalized dihydrocarbazoles and cyclohepta[cd]indoles in formal [3 + 3] and [4 + 3]-cycloadditions A minor modification to the reaction conditions also allowed access to the fully aromatic heterocyclic scaffolds by thermal loss of an electron-rich aryl moiety.Trimethylsulfoxonium iodide(cas: 1774-47-6Recommanded Product: Trimethylsulfoxonium iodide) was used in this study.

Trimethylsulfoxonium iodide(cas: 1774-47-6) is a sulfoxonium salt. It is used to generate dimethyloxosulfonium methylide by reaction with sodium hydride. The latter compound is used as a methylene-transfer reagent, and is used to prepare epoxides.Recommanded Product: Trimethylsulfoxonium iodide

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zubar, Viktoriia; Brzozowska, Aleksandra; Sklyaruk, Jan; Rueping, Magnus published an article in 2022. The article was titled 《Dehydrogenative and Redox-Neutral N-Heterocyclization of Aminoalcohols Catalyzed by Manganese Pincer Complexes》, and you may find the article in Organometallics.Recommanded Product: 4-Chloro-2-iodoaniline The information in the text is summarized as follows:

A new Mn catalyzed heterocyclization of aminoalcs. was accomplished. A wide range of heterocycles were synthesized including, 1,2,3,4-tetrahydroquinolines, dihydroquinolinones and 2,3,4,5-tetrahydro-1H-benzo[b]azepines. The reaction was performed under mild reaction conditions using air and moisture stable Mn catalysts. The desired heterocycles were obtained in good to excellent yields.4-Chloro-2-iodoaniline(cas: 63069-48-7Recommanded Product: 4-Chloro-2-iodoaniline) was used in this study.

4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Hydrogen peroxide (H2O2) and peroxy acids generally add an oxygen atom to the nitrogen of amines. With primary amines, this step is normally followed by further oxidation, leading to nitroso compounds, RNO, or nitro compounds, RNO2. Secondary amines are converted to hydroxylamines, R2NOH, and tertiary amines to amine oxides, R3NO.Recommanded Product: 4-Chloro-2-iodoaniline

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com