Month: October 2022

In 2015,Fernandez Saez, Nerea; Garcia Lopez, Jesus; Iglesias, Maria Jose; Lopez Ortiz, Fernando published 《Derivatization of (quinolin-8-yl)phosphinimidic amides via ortho-lithiation revisited》.Dalton Transactions published the findings.Formula: C2H4I2 The information in the text is summarized as follows:

The direct ortho-lithiation of N-H containing (quinolin-8-yl)phosphinimidic amides by reaction with 1 equiv of BuLi described by Wang and co-workers was reexamined The multinuclear magnetic resonance (1H, 2H, 7Li, 13C, 15N and 31P) study of the species formed in the monolithiation of N-(tert-butyl)-P,P-diphenyl-N’-(quinolin-8-yl)phosphinimidic amide 5 with BuLi in THF showed that proton abstraction occurred exclusively and quant. at the NH. The combination of the NMR results with a DFT study made it possible to describe the structure of the N-lithiated species 9 as a dimer consisting of an eight-membered ring showing two lithium ions triply coordinated to nitrogen atoms corresponding to the deprotonated amine and aminoquinoline moieties of different monomers. The formation of a polymer featuring the same coordination mode couldn’t be excluded. Optimized conditions for the efficient derivatization of 5 via ortho-lithiation were realized. The reaction of 5 with 2.4 equiv of Me3CLi in THF at -80-25° for 3 h afforded a N,Cortho-dilithiated species that was trapped with electrophiles leading to new functionalized ortho derivatives of 5 in good yields. In addition to this study using 1,2-Diiodoethane, there are many other studies that have used 1,2-Diiodoethane(cas: 624-73-7Formula: C2H4I2) was used in this study.

1,2-Diiodoethane(cas: 624-73-7) is one of organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Formula: C2H4I2

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Advanced Synthesis & Catalysis included an article by Xie, Jialin; Guo, Zhonglin; Huang, Yuanqiong; Qu, Yi; Song, Hongjian; Song, Haibin; Liu, Yuxiu; Wang, Qingmin. Name: 1-Iodonaphthalene. The article was titled 《One-Pot Copper-Catalyzed Cascade Bicyclization Strategy for Synthesis of 2-(1H-Indol-1-yl)-4,5-dihydrothiazoles and 2-(1H-Indol-1-yl)thiazol-5-yl Aryl Ketones with Molecular Oxygen as an Oxygen Source》. The information in the text is summarized as follows:

An atom-economical method for synthesizing N-heterocyclic indoles from readily available o-alkynylphenyl isothiocyanates and propargylamine derivatives is reported. This method involves a copper-catalyzed cascade bicyclization process consisting of an intramol. 5-exo-dig hydrothiolation reaction and an intramol. hydroamination reaction and, depending on whether or not mol. oxygen is present, selectively affords Z-isomers of 2-(1H-indol-1-yl)-4,5-dihydrothiazoles, e.g., I (X-rays single crystal structure shown), or 2-(1H-indol-1-yl)thiazol-5-yl aryl ketones in satisfactory yields. Mechanistic studies indicate that mol. oxygen acts as the oxygen source for the ketone moiety in the products.1-Iodonaphthalene(cas: 90-14-2Name: 1-Iodonaphthalene) was used in this study.

1-Iodonaphthalene(cas: 90-14-2) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Name: 1-Iodonaphthalene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Chinese Journal of Chemistry included an article by Hong, Junting; Liu, Qianyi; Li, Feng; Bai, Guangcan; Liu, Guoquan; Li, Man; Nayal, Onkar S.; Fu, Xuefeng; Mo, Fanyang. Recommanded Product: 1-Iodonaphthalene. The article was titled 《Electrochemical Radical Borylation of Aryl Iodides》. The information in the text is summarized as follows:

Summary of main observation and conclusion : Herein, we report the first electrochem. strategy for the borylation of aryl iodides via a radical pathway using current as a driving force. A mild reaction condition allows an assorted range of readily available aryl iodides to be proficiently converted into synthetically valuable arylboronic esters under transition metal catalyst-free conditions. Moreover, this method also shows good functional group tolerance. Initial control mechanistic experiments reveal the formation of aryl radical as a key intermediate and the current plays an important role in the generation of radical intermediate. The results came from multiple reactions, including the reaction of 1-Iodonaphthalene(cas: 90-14-2Recommanded Product: 1-Iodonaphthalene)

1-Iodonaphthalene(cas: 90-14-2) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Recommanded Product: 1-Iodonaphthalene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

In 2019,Advanced Synthesis & Catalysis included an article by Yu, Dezhong; Xu, Fangning; Li, Dan; Han, Wei. Synthetic Route of C10H7I. The article was titled 《Transition-Metal-Free Carbonylative Suzuki-Miyaura Reactions of Aryl Iodides with Arylboronic Acids Using N-Formylsaccharin as CO Surrogate》. The information in the text is summarized as follows:

Unprecedented, high yielding, transition-metal-free carbonylative Suzuki-Miyaura reactions of aryl iodides with arylboronic acids using N-formylsaccharin as CO surrogate have been developed. Notably, this general protocol was adapted to the synthesis of the triglyceride and cholesterol regulator drug, fenofibrate, and carbon-13 labeled biaryl ketone. In addition to this study using 1-Iodonaphthalene, there are many other studies that have used 1-Iodonaphthalene(cas: 90-14-2Synthetic Route of C10H7I) was used in this study.

1-Iodonaphthalene(cas: 90-14-2) is one of organic iodides. Organic iodides are used in veterinary products (Organic Iodide Powder) as a nutritional source of iodine. In the chemical industry, alkyl iodides serve as excellent alkylating agents and, specifically, methyl iodide is used as a methylating agent in the synthesis of various pharmaceutical drugs. Oceanic alkyl iodides are believed to be the principal source of atmospheric iodine.Synthetic Route of C10H7I

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

The author of 《Quaternized poly(arylene perfluoroalkylene)s (QPAFs) for alkaline fuel cells – a perspective》 were Miyake, Junpei; Miyatake, Kenji. And the article was published in Sustainable Energy & Fuels in 2019. HPLC of Formula: 625-99-0 The author mentioned the following in the article:

The recent progress of our research on quaternized poly(arylene perfluoroalkylene)s (QPAFs) as anion exchange membranes (AEMs) for alk. fuel cell applications is reviewed. First, the effect of the perfluoroalkylene group in the polymer main chains on the AEM properties is discussed. We emphasize that the polymer main chains of QPAFs remain intact in harsh alk. environments, and QPAFs have desirable AEM properties, such as well-developed phase-separated morphol., good anion transport, mech. robustness, and gas barrier properties. We then discuss the effect of the mol. structures of the quaternary ammonium groups on the alk. stability of the QPAF membranes. A number of pendant ammonium head groups are much more alk.-stable than the classical benzyltrimethylammonium groups. A comparison of our QPAFs with other state-of-the-art AEMs implies that well-designed aromatic AEMs are potentially applicable for alk. fuel cells that use hydrogen or hydrazine as a fuel. The experimental part of the paper was very detailed, including the reaction process of 1-Chloro-3-iodobenzene(cas: 625-99-0HPLC of Formula: 625-99-0)

1-Chloro-3-iodobenzene(cas: 625-99-0) belongs to organic iodides. Alkyl iodides react at a faster rate than alkyl fluorides due to the weak C-I bond.Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.HPLC of Formula: 625-99-0

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Lewis Acid Catalyzed Atom-Economic Synthesis of C2-Substituted Indoles from o-Amido Alkynols》 was written by Garkhedkar, Amol Milind; Gore, Babasaheb Sopan; Hu, Wan-Ping; Wang, Jeh-Jeng. Recommanded Product: 4-Chloro-2-iodoaniline And the article was included in Organic Letters in 2020. The article conveys some information:

Herein a Zn(OTf)2 catalyzed synthesis of C2-alkyl substituted indole derivatives I (R = H, 6-Me, 5-F, etc.; R1 = H, 3-OMe, 4-Cl, etc.; n = 1, 2, 3) via unprecedented carbonyl group migration from o-amido alkynols is reported. The key features of this protocol involve N,O-carbonyl group migration, broad substrate scope with varied functionality tolerance, moderate to good yields, and 100% atom economy. The crossover experiments proved that the migration is happening via an intramol. pathway. In the experiment, the researchers used 4-Chloro-2-iodoaniline(cas: 63069-48-7Recommanded Product: 4-Chloro-2-iodoaniline)

4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Examples of direct uses of amines and their salts are as corrosion inhibitors in boilers and in lubricating oils (morpholine), as antioxidants for rubber and roofing asphalt (diarylamines), as stabilizers for cellulose nitrate explosives (diphenylamine), as protectants against damage from gamma radiation (diarylamines), as developers in photography (aromatic diamines), as flotation agents in mining, as anticling and waterproofing agents for textiles, as fabric softeners, in paper coating, and for solubilizing herbicides.Recommanded Product: 4-Chloro-2-iodoaniline

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Controllable Synthesis of NiS/rGO Hybrid Composite: An Excellent Counter Electrode for Dye Sensitized Solar Cell》 was written by Indhumathy, M.; Prakasam, A.. Product Details of 516-12-1 And the article was included in Journal of Cluster Science in 2020. The article conveys some information:

We have synthesized an efficient NiS anchored reduced graphene oxide (rGO) nanosheet composites were by a facile hydrothermal route and served as the efficient counter electrodes (CE) for dye-sensitized solar cells (DSSCs). XRD and FESEM results suggest that the electrodes were well crystalline with formation of individual spherical like with homogeneous nanoparticles sizes in the range of 40-30 nm, which is distributed throughout the rGO sheet. The UV-Vis DRS suggest that the absorption edge of all the electrodes were in the visible light region, further it was shifted in the longer wavelength side with the increase of rGO content. The separation, transfer and recombination behavior of the photogenerated charge carriers were analyzed by PL spectra. The NiS/rGO CE produces a power conversion efficiency of 9.25%, which is higher than that (5.21%) for the DSSC with the bare CE. The enhanced efficiency of NiS/rGO hybrid composite is due to reduction of the triiodide caused by the synergistic effects between the extremely catalytic NiS nanoparticles and high elec. conductive nature of rGO sheet. In the experiment, the researchers used 1-Iodopyrrolidine-2,5-dione(cas: 516-12-1Product Details of 516-12-1)

1-Iodopyrrolidine-2,5-dione(cas: 516-12-1) is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively. Product Details of 516-12-1

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

《Palladium fabricated on boehmite as an organic-inorganic hybrid nanocatalyst for C-C cross coupling and homoselective cycloaddition reactions》 was written by Tahmasbi, Bahman; Ghorbani-Choghamarani, Arash; Moradi, Parisa. Quality Control of 1-Iodo-4-methylbenzene And the article was included in New Journal of Chemistry in 2020. The article conveys some information:

Herein, boehmite nanoparticles were prepared using an aqueous solution of NaOH and Al(NO3)3·9H2O at room temperature After modification of the boehmite nanoparticle (BNP) surface by 3-choloropropyltrimtoxysilane (CPTMS), adenine was anchored on the surface. Finally, a complex of palladium was fabricated on the BNP surface (Pd-adenine@boehmite). The obtained nanoparticles were identified by TGA, FT-IR, BET, EDS, WDX, SEM, XRD and AAS techniques. In continuation, the Pd-adenine@boehmite was employed as an efficient, reusable and organic-inorganic hybrid catalyst in the C-C cross coupling reactions without a phosphine ligand or an inert atm. Moreover, the homoselective synthesis of tetrazoles was studied in the presence of Pd-adenine@boehmite as a heterogeneous and practical nanocatalyst which can be recovered and reused in the described organic reactions. Besides, organic products which were isolated in suitable TOF and TON numbers in the presence of Pd-adenine@boehmite as a catalyst revealed the practicality of this catalyst. The heterogeneous nature of this catalyst was confirmed by TEM, EDS, WDX, AAS, and FT-IR techniques and, then, compared to the fresh catalyst. In addition to this study using 1-Iodo-4-methylbenzene, there are many other studies that have used 1-Iodo-4-methylbenzene(cas: 624-31-7Quality Control of 1-Iodo-4-methylbenzene) was used in this study.

1-Iodo-4-methylbenzene(cas: 624-31-7) is used in wide range of medicals industrial applications as well as in pharmaceutical intermediates, polarizing films for Liquid Crystal Display (LCD) chemicals.Quality Control of 1-Iodo-4-methylbenzene

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Zhao, Haiwei; Lu, Changhui; Herbert, Simon; Zhang, Wei; Shen, Qilong published their research in Journal of Organic Chemistry in 2021. The article was titled 《Difluoromethylation of Alkyl Bromides and Iodides with TMSCF2H》.Application of 619-58-9 The article contains the following contents:

For the first time, two protocols for direct difluoromethylation of unactivated alkyl bromides and iodides RCH2X [R = 4-phenylbutyl, 3-[(5-methylthiophen-2-yl)carbonyloxy]propyl, dodecyl, etc.; X = Br, I, OTs] were described. Reactions of alkyl iodides with TMSCF2H were mediated by a copper catalyst using CsF as the activator, while reactions of less reactive alkyl bromides required a combination of palladium and a stoichiometric amount of CuI as the catalysts. Preliminary mechanistic studies of the synergistic Pd/Cu-catalyzed difluoromethylation of alkyl bromides suggest that it proceeds likely via a Pd(I)/Pd(III) catalytic cycle. In addition to this study using 4-Iodobenzoic acid, there are many other studies that have used 4-Iodobenzoic acid(cas: 619-58-9Application of 619-58-9) was used in this study.

4-Iodobenzoic acid(cas: 619-58-9) belongs to organic iodides. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics.Application of 619-58-9Halogenation of aromatic hydrocarbons is a very important reaction via an electrophilic aromatic substitution.

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chen, Su; Oliva, Monica; Van Meervelt, Luc; Van der Eycken, Erik V.; Sharma, Upendra K. published an article in 2021. The article was titled 《Palladium-Catalyzed Domino Synthesis of 2,3-Difunctionalized Indoles via Migratory Insertion of Isocyanides in Batch and Continuous Flow》, and you may find the article in Advanced Synthesis & Catalysis.Related Products of 63069-48-7 The information in the text is summarized as follows:

Authors report, herein, a palladium-catalyzed cascade comprising carbopalladation, migratory insertion of isocyanide and triple bond activation followed by a nucleophilic attack to construct difunctionalized acyl indoles e.g. I. The process involves multiple bond formations via key palladium-chem. steps, to construct these bis-heterocycles containing two privileged scaffolds (indole and oxindole) in a single operational step, along with attempts to generate enantioselectivity at a quaternary carbon center. The methodol. also demonstrates a continuous-flow process to synthesize aryl isocyanides within minutes and using them in a telescopic manner. In the experiment, the researchers used 4-Chloro-2-iodoaniline(cas: 63069-48-7Related Products of 63069-48-7)

4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Large quantities of aliphatic amines are made synthetically. The most widely used industrial method is the reaction of alcohols with ammonia at a high temperature, catalyzed by metals or metal oxide catalysts (e.g., nickel or copper). Mixtures of primary, secondary, and tertiary amines are thereby produced.Related Products of 63069-48-7

Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com