Month: November 2022

Yu, Shuling published the artcileSynthesis of Cyclopentenones through Rhodium-Catalyzed C-H Annulation of Acrylic Acids with Formaldehyde and Malonates, Application In Synthesis of 638-45-9, the publication is Organic Letters (2021), 23(13), 5054-5059, database is CAplus and MEDLINE.

An efficient rhodium-catalyzed protocol for the synthesis of cyclopentenones I (R¹ = Et, Bn, c-hexyl, etc.; R² = H, Me, Et, Ph; -R¹R²– = -(CH₂)₃-, -(CH₂)₄-; R³ = Me, Et, n-Pr, i-Pr, n-Bu) based on a three-component reaction of acrylic acids, formaldehyde, and malonates via vinylic C-H activation is reported. Exploratory studies showed that 5-alkylation of as-prepared cyclopentenones could be realized smoothly by the treatment of a variety of alkyl halides with a Na₂CO₃/MeOH solution Excess formaldehyde and malonate led to a multicomponent reaction that afforded the multisubstituted cyclopentenones II (R¹ = n-Bu, 3-FC₆H₄, Ph(CH₂)₂, etc.; R² = H, Me, Et, etc.; R³ = Me, Et, n-Pr, i-Pr; -R¹R²– = -(CH₂)₄-) through a Michael addition

Organic Letters published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C7H10O4, Application In Synthesis of 638-45-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Chen, Zhiwei published the artcileConstruction of Polycyclic β-Ketoesters Using a Homoconjugate Addition/Decarboxylative Dieckmann Annulation Strategy, COA of Formula: C10H9IO4, the publication is Journal of Organic Chemistry (2018), 83(11), 6225-6234, database is CAplus and MEDLINE.

The construction of arene-fused cyclic β-ketoesters from 2-iodoaryl esters and 1,1-cyclopropane diesters is detailed. The synthetic method takes advantage of a CuI·SMe₂-mediated homoconjugate addition followed by a decarboxylative Dieckmann cyclization to afford valuable polycyclic building blocks. Various iodoaryl esters and 1,1-cyclopropane diesters were evaluated, and the limitations of both reactions are discussed. Several mechanistic probes are detailed and synthetic applications are described.

Journal of Organic Chemistry published new progress about 165534-79-2. 165534-79-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Benzene,Ester, name is Dimethyl 2-iodoterephthalate, and the molecular formula is C10H9IO4, COA of Formula: C10H9IO4.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Wynter, Clive I. published the artcileMoessbauer effect of iodine-129 in pyridine complexes of iodine monohalides, Safety of Pyridine Iodochloride complex, the publication is Journal of Chemical Physics (1969), 50(9), 3872-4, database is CAplus.

The values of isomer shift and quadrupole interaction at the 129I nucleus in IBr and ICl complexes with cyclic N bases have been measured. These have been used to estimate σ and π bondings in these complexes. All these complexes exhibit a linear N-I-X (X = Cl, Br) linkage. Although the Br complexes show a systematic dependence of the isomer shift on the basicity of the complexing cyclic amines, no such trend is observed in Cl complexes.

Journal of Chemical Physics published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C6H12F3NO5S, Safety of Pyridine Iodochloride complex.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Hammoud, Fatima published the artcileChemical engineering around the 5,12-dihydroindolo[3,2-a]carbazole scaffold: Fine tuning of the optical properties of visible light photoinitiators of polymerization, Quality Control of 638-45-9, the publication is European Polymer Journal (2022), 111218, database is CAplus.

5,12-Dihydroindolo[3,2-a]carbazole is a promising scaffold for the design of visible light photoinitiators of polymerization due to the simultaneous presence of two carbazole moieties that can be differently functionalized. Notably, red shift of the absorption spectra can be facilely obtained by nitration of one of the two carbazoles, the second carbazole group being functionalized with various groups. Dinitration of 5,12-dihydroindolo[3,2-a]carbazole is another efficient approach for designing dyes with strong absorptions extending over the visible range. In this work, a series of 36 compounds never reported in the literature and differing by the substitution pattern have been designed and synthesized. Notably, the possibility to design push-pull dyes by Knoevenagel and Claisen Schmidt reactions, to introduce electroactive groups such as thiophene by Suzuki cross-coupling reactions or to design water soluble chromophore has been explored. To evidence the interest of these structures, photopolymerization experiments have been carried out at 405 nm and the polymerization of acrylates has been examined in thick and thin films. To support the polymerization efficiency, mechanisms involved in the free radical polymerization of acrylates have been established by the combination of various techniques including UV-visible absorption and fluorescence spectroscopy, cyclic voltammetry and photolysis experiments

European Polymer Journal published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Quality Control of 638-45-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Cox, Philip J. published the artcile3,5-Diiodo-4-oxo-1,4-dihydropyridine-1-acetic acid, Related Products of iodides-buliding-blocks, the publication is Acta Crystallographica, Section E: Structure Reports Online (2001), 57(6), o495-o497, database is CAplus.

In the title compound, C₇H₅I₂NO₃, catemeric H bonding is present involving the carboxyl group of one mol. and the ketone group of a translationally related neighbor. Crystallog. data are given.

Acta Crystallographica, Section E: Structure Reports Online published new progress about 101-29-1. 101-29-1 belongs to iodides-buliding-blocks, auxiliary class Pyridine,Iodide,Carboxylic acid,Ketone, name is 2-(3,5-Diiodo-4-oxopyridin-1(4H)-yl)acetic acid, and the molecular formula is C7H5I2NO3, Related Products of iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Roychowdhury, Pritam published the artcileTraceless Benzylic C-H Amination via Bifunctional N-Aminopyridinium Intermediates, Synthetic Route of 638-45-9, the publication is Angewandte Chemie, International Edition (2022), 61(28), e202200665, database is CAplus and MEDLINE.

Here, traceless nitrogen activation for C-H amination-which enables application of selective C-H amination chem. to the preparation of diverse N-functionalized products-via sequential benzylic C-H N-aminopyridylation followed by Ni-catalyzed C-N cross-coupling with aryl boronic acids was introduced. Unlike many C-H amination reactions that provide access to protected amines, the current method installs an easily diversifiable synthetic handle that serves as a lynchpin for C-H amination, deaminative N-N functionalization sequences.

Angewandte Chemie, International Edition published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Synthetic Route of 638-45-9.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Pande, Gaurav K. published the artcileRGB-to-black multicolor electrochromic devices enabled with viologen functionalized polyhedral oligomeric silsesquioxanes, Product Details of C6H13I, the publication is Chemical Engineering Journal (Amsterdam, Netherlands) (2021), 420(Part_3), 130446, database is CAplus.

Here we demonstrate multicolor electrochromic transitions of viologen functionalized polyhedral oligomeric silsesquioxanes (POSS-viologens). Highly efficient RGB coverage, including black, was successfully achieved with POSS-viologen employed multi-stacked electrochromic devices (ECDs). We prepared octa-viologen functionalized POSS (OHV-POSS) with the insertion of thiophene (OTxHV-POSS) and Ph (OPhHV-POSS) moiety. The single-layer ion gel ECDs exhibited outstanding electrochromic performances. OTxHV-POSS and OHV-POSS showed red (R) and blue (B) transitions, resp., with high transmittance changes and superb coloration efficiency. Saturated green (G) was also obtained from the mixture of OPhHV-POSS and OHV-POSS. Furthermore, multi-stacked ECDs were implemented by combining the RGB coloration layers with multiple electrodes. The two-layer ECDs generated intermediate colors, which was fully translated into the color mixing theory. The three-layer device created real black with blackness L^* of 6.99, covering 12.9% of the NTSC color gamut. The unprecedented RGB-to-black multicolor coverage, not reported elsewhere, is attributable to the reversible color-switching at a low redox potential for extended cyclic operations. Current findings imply that carefully designed POSS-viologens offer a universal route to high-performance and stable multicolor ECDs, offering compatibility with various pixelized color-changing displays and smart windows.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Product Details of C6H13I.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Szczesniak, Pawel published the artcileExtracellular MIF, but not its homologue D-DT, promotes fibroblast motility independently of its receptor complex CD74/CD44, Category: iodides-buliding-blocks, the publication is Journal of Cell Science (2021), 134(3), jcs217356, database is CAplus and MEDLINE.

Macrophage migration inhibitory factor (MIF) and its homolog D-dopachrome tautomerase (D-DT) are widely expressed pro-inflammatory cytokines with chemokine-like functions that coordinate a wide spectrum of biol. activities, such as migration. Here, we biotin-tagged intracellular MIF/D-DT in vivo to identify important cytosolic interactors and found a plethora of actin cytoskeleton-associated proteins. Although the receptor complex between CD74 and CD44 (CD74/CD44) is essential for signalling transduction in fibroblasts via extracellular MIF/D-DT, our interactome data suggested direct effects. We, thus, investigated whether MIF/D-DT can modulate cell migration independently of CD74/CD44. To distinguish between receptor- and non-receptor-mediated motility, we used fibroblasts that are either deficient or that express CD74/CD44 proteins, and treated them with recombinant MIF/D-DT. Interestingly, only MIF could stimulate chemokinesis in the presence or absence of CD74/CD44. The pro-migratory effects of MIF depended on lipid raft/caveolae-mediated but not clathrin-mediated endocytosis, on its tautomerase activity and, probably, on its thiol protein oxidoreductase activity. As MIF treatment restrained actin polymerization in vitro, our findings establish a new intracellular role for MIF/D-DT in driving cell motility through modulation of the actin cytoskeleton.

Journal of Cell Science published new progress about 41270-96-6. 41270-96-6 belongs to iodides-buliding-blocks, auxiliary class Pyrimidine,Iodide,Benzene,Immunology/Inflammation,MIF, name is 4-Iodo-6-phenylpyrimidine, and the molecular formula is C5H8N2O, Category: iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Anil Kumar, G. N. published the artcileQuantitative Investigation of Halogen and Hydrogen Bonding in 2-Chloro, 4-X-Benzoic Acids, Application In Synthesis of 145343-76-6, the publication is ChemistrySelect (2022), 7(3), e202104338, database is CAplus.

The crystal structure, Hirshfeldsurface anal., topol. anal. of the electron d. and total interaction energies of four compounds, 2-Chloro, 4-X-Benzoic Acids (where X=I, Br, Cl and F) have been analyzed. The packing similarity was evaluated in all compounds using the XPac anal. The qual. information about intermol. interactions is derived from the crystal structure and Hirshfeld surface analyses whereas quant. information are determined by the QTAIM anal. as well as total interaction energies from CrystalExplorer. The topol. properties are estimated for all compounds in both crystal geometry and gas phase using TOPOND and AIMALL, resp. The carboxylic acid O-H···O HB dimers, C-H···O HBs and Cπ···Cπ aromatic stacking interactions are found to be common interactions in all compounds The topol. properties and bond paths demonstrate them as non-covalent stabilizing interactions in the crystalline state. The hierarchy of interactions concerning their strength is observed in the following order such that O-H···O HB dimers>C_π···C_π aromatic stacking interactions>C-H···O HBs>Type II X···Cl interactions and C-H···Cl HBs>Type I homo-halogen X···X interactions in all compounds Addnl., the strength of Type I homo-halogen X···X interactions vary in the order: I···I>Br···Br>Cl···Cl>F···F. The hierarchy of interactions is further supported by mol. electrostatic potential surfaces associated with both pos. and neg. potential regions.

ChemistrySelect published new progress about 145343-76-6. 145343-76-6 belongs to iodides-buliding-blocks, auxiliary class Chloride,Iodide,Carboxylic acid,Benzene, name is 2-Chloro-4-iodobenzoic acid, and the molecular formula is C7H4ClIO2, Application In Synthesis of 145343-76-6.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

El Maghraby, M. A. published the artcileStyryl and dicationic cyanine dyes incorporating pyrazole moiety, Application of 1-Ethyl-2-methylquinolin-1-ium iodide, the publication is Aswan Science & Technology Bulletin (1991), 24-38, database is CAplus.

I (R = H, Ph, Ac, Bz; X = 1-ethylquinolinium-2-yl iodide, 1-ethylpyridinium-2-yl iodide), II (R’ = H, Ph; Y = NO₂, NMe₂), and III (R’, X, Y as above) were obtained from 3,5-dimethylpyrazoles.

Aswan Science & Technology Bulletin published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Application of 1-Ethyl-2-methylquinolin-1-ium iodide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com