Pelcman, Benjamin’s team published research in Bioorganic & Medicinal Chemistry Letters in 25 | CAS: 141998-77-8

Bioorganic & Medicinal Chemistry Letters published new progress about 141998-77-8. 141998-77-8 belongs to iodides-buliding-blocks, auxiliary class Pyrazole,Iodide,Ester,Pyrazole, name is Ethyl 5-iodo-1H-pyrazole-3-carboxylate, and the molecular formula is C6H7IN2O2, Computed Properties of 141998-77-8.

Pelcman, Benjamin published the artcile3-Substituted pyrazoles and 4-substituted triazoles as inhibitors of human 15-lipoxygenase-1, Computed Properties of 141998-77-8, the publication is Bioorganic & Medicinal Chemistry Letters (2015), 25(15), 3024-3029, database is CAplus and MEDLINE.

Investigation of 1N-substituted pyrazole-3-carboxanilides as 15-lipoxygenase-1 (15-LOX-1) inhibitors demonstrated that the 1N-substituent was not essential for activity or selectivity. Addnl. halogen substituents on the pyrazole ring, however, increased activity. Further development led to triazole-4-carboxanilides and 2-(3-pyrazolyl) benzoxazoles, which are potent and selective 15-LOX-1 inhibitors.

Bioorganic & Medicinal Chemistry Letters published new progress about 141998-77-8. 141998-77-8 belongs to iodides-buliding-blocks, auxiliary class Pyrazole,Iodide,Ester,Pyrazole, name is Ethyl 5-iodo-1H-pyrazole-3-carboxylate, and the molecular formula is C6H7IN2O2, Computed Properties of 141998-77-8.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Nagrimanov, Ruslan N.’s team published research in Thermochimica Acta in 710 | CAS: 638-45-9

Thermochimica Acta published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Safety of 1-Iodohexane.

Nagrimanov, Ruslan N. published the artcileAdditive scheme of solvation enthalpy for halogenated aliphatic hydrocarbons at 298.15 K., Safety of 1-Iodohexane, the publication is Thermochimica Acta (2022), 179155, database is CAplus.

In this work, an additive scheme for the estimation of solvation enthalpy of halogenated aliphatic hydrocarbons in n-heptane was developed. The proposed structural fragments for halogen group contributions are dependent on the nature of neighboring atoms. A linear relationship between solvation and vaporization enthalpy at 298.15 K for mono- and di-α,ω-halogen aliphatic compounds was found. These relationships can be used for the quick estimation of standard vaporization and solution enthalpies at 298.15 K. Proposed approaches for estimation of solvation, solution and vaporization enthalpies at 298.15 K were verified by conventional methods. In most cases, absolute deviations between exptl. and estimated values for halogenated aliphatic hydrocarbons do not exceed 1-2 kJ mol-1.

Thermochimica Acta published new progress about 638-45-9. 638-45-9 belongs to iodides-buliding-blocks, auxiliary class Iodide,Aliphatic hydrocarbon chain, name is 1-Iodohexane, and the molecular formula is C6H13I, Safety of 1-Iodohexane.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Andrade, Carolina Horta’s team published research in Letters in Drug Design & Discovery in 5 | CAS: 39115-95-2

Letters in Drug Design & Discovery published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Name: 4-Iodobenzohydrazide.

Andrade, Carolina Horta published the artcileThree-dimensional quantitative structure-activity relationships for a large series of potent antitubercular agents, Name: 4-Iodobenzohydrazide, the publication is Letters in Drug Design & Discovery (2008), 5(6), 377-387, database is CAplus.

Comparative mol. field anal. (CoMFA) studies were conducted on a series of 100 isoniazid derivatives as anti-tuberculosis agents using two receptor-independent structural data set alignment strategies: (1) rigid-body fit, and (2) pharmacophore-based. Significant cross-validated correlation coefficients were obtained (CoMFA(1), q2 = 0,75 and CoMFA(2), q2 = 0.74), indicating the potential of the models for untested compounds The models were then used to predict the inhibitory potency of 20 test set compounds that were not included in the training set, and the predicted values were in good agreement with the exptl. results.

Letters in Drug Design & Discovery published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Name: 4-Iodobenzohydrazide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Andrade, Carolina H.’s team published research in Molecular Diversity in 12 | CAS: 39115-95-2

Molecular Diversity published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Recommanded Product: 4-Iodobenzohydrazide.

Andrade, Carolina H. published the artcileFragment-based and classical quantitative structure-activity relationships for a series of hydrazides as antituberculosis agents, Recommanded Product: 4-Iodobenzohydrazide, the publication is Molecular Diversity (2008), 12(1), 47-59, database is CAplus and MEDLINE.

Worldwide, tuberculosis (TB) is the leading cause of death among curable infectious diseases. Multidrug-resistant Mycobacterium tuberculosis is an emerging problem of great importance to public health, and there is an urgent need for new anti-TB drugs. In the present work, classical 2D quant. structure-activity relationships (QSAR) and hologram QSAR (HQSAR) studies were performed on a training set of 91 isoniazid derivatives Significant statistical models (classical QSAR, q 2 = 0.68 and r 2 = 0.72; HQSAR, q 2 = 0.63 and r 2 = 0.86) were obtained, indicating their consistency for untested compounds The models were then used to evaluate an external test set containing 24 compounds which were not included in the training set, and the predicted values were in good agreement with the exptl. results (HQSAR,; classical QSAR).

Molecular Diversity published new progress about 39115-95-2. 39115-95-2 belongs to iodides-buliding-blocks, auxiliary class Iodide,Hydrazine,Amine,Benzene,Hydrazide,Amide, name is 4-Iodobenzohydrazide, and the molecular formula is C7H7IN2O, Recommanded Product: 4-Iodobenzohydrazide.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Patnaik, Lalit N.’s team published research in Journal of Solution Chemistry in 23 | CAS: 606-55-3

Journal of Solution Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, HPLC of Formula: 606-55-3.

Patnaik, Lalit N. published the artcileSolvent effects on the absorption spectra of merocyanine dyes, HPLC of Formula: 606-55-3, the publication is Journal of Solution Chemistry (1994), 23(12), 1317-30, database is CAplus.

Solvent effects on the lowest-energy electronic transitions of 2 merocyanines derived from quinoline were studied using 9 different solvent parameters reported in the literature. Relative merits and deficiencies of different parameters were assessed. From the correlation results, attempts were made to propose a solute-solvent interaction mechanism. For an assorted set of 19 solvents, as well as for a set of 9 hydroxylic solvents, excellent results are obtained with correlation equation involving ET(30) and Hilderbrand’s solubility parameter δH.

Journal of Solution Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, HPLC of Formula: 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Jouanno, Laurie-Anne’s team published research in Journal of Organic Chemistry in 77 | CAS: 31253-08-4

Journal of Organic Chemistry published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Safety of Ethyl 2-Iodopropionate.

Jouanno, Laurie-Anne published the artcileExpeditious Microwave-Assisted Synthesis of 5-Alkoxyoxazoles from α-Triflyloxy Esters and Nitriles, Safety of Ethyl 2-Iodopropionate, the publication is Journal of Organic Chemistry (2012), 77(19), 8549-8555, database is CAplus and MEDLINE.

A rapid and general access to diversely substituted 5-alkoxyoxazoles from easily accessible α-triflyloxy/hydroxy esters and nitriles with good yields (41-76%) is reported. The versatility of the cyclization is shown for a range of substrates with high selectivity toward triflates over tosylates and proved to be compatible with sensitive functional groups. As an illustration of this transformation, the first synthesis of the recently isolated hydroxypyridine Me multijuguinate (I) was achieved in four steps through a hetero Diels-Alder reaction of the 5-alkoxyoxazole II and acrylic acid, followed by a protodecarboxylation reaction.

Journal of Organic Chemistry published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Safety of Ethyl 2-Iodopropionate.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Abd El-Aal, R. M.’s team published research in Arabian Journal of Chemistry in 10 | CAS: 606-55-3

Arabian Journal of Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Quality Control of 606-55-3.

Abd El-Aal, R. M. published the artcileSynthesis and physicochemical studies of some new quinolinoxazine pentamethine cyanine dyes, Quality Control of 606-55-3, the publication is Arabian Journal of Chemistry (2017), 10(1), 82-90, database is CAplus.

Polymethine cyanine dyes belong to a well-known class of organic compounds, which have been used in photog. and as information storage in laser technol. A series of novel cyanine dyes were synthesized through the formylation of quinolinium[b,c]1,4-oxazine-chloride salt 1. Reaction of compound 2-chloro-3-formyl-quinolinium[b,c]1,4-oxazine-chloride salt 2 with different molar ratios of 2(4)-Me substituted heterocyclic in basic catalysis afforded the corresponding 2-chloroquinolinium[b,c]1,4-oxazine-chloride salt-3[2(4)]-dimethine (3a-c), quinolinium[b,c]-1,4-oxazinechloride salt-2,3[2(4)]-pentamethine (4a-c) and quinolino[b,c]1,4-oxazine-6yl[2(4)]-monomethine-/2,3[2(4)]-pentamethine cyanine dyes (5a-c) resp. The structure of the dyes was characterized by elemental anal., visible absorption, fluorescence emission, IR, 1H-NMR and mass spectroscopy. A comparison of the visible absorption maxima between compounds 3b, 4b and 5b showed that asym. mono-pentamethine cyanine dye 5b reveals a bathochromic shift than both dimethine 3b and pentamethine cyanine dyes 4b. The absorption spectra of dyes were investigated in organic solvents. The results indicated that the excitation for their color is a simple charge-transfer from oxygen atom of oxazine nucleus and/or nitrogen atom of pyridine (quinoline) nucleus to N-quaternary salts in di-, penta- and mono-/pentamethine cyanine dyes resp. These dyes showed pos. solvatochromism with increased solvent polarity.

Arabian Journal of Chemistry published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Quality Control of 606-55-3.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Popov, Alexander I.’s team published research in Journal of the American Chemical Society in 79 | CAS: 6443-90-9

Journal of the American Chemical Society published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, Recommanded Product: Pyridine Iodochloride complex.

Popov, Alexander I. published the artcileThe chemistry of halogens and of polyhalides. XI. Molecular complexes of pyridine, 2-picoline, and 2,6-lutidine with iodine and iodine halides, Recommanded Product: Pyridine Iodochloride complex, the publication is Journal of the American Chemical Society (1957), 4622-5, database is CAplus.

cf. C.A. 51, 7931a. Crystalline addition compounds of 2-picoline, 2,6-lutidine, and pyridine were prepared with ICI and IBr. The dissociation constants of these 6 compounds and of the 3 mol. complexes, amine-I2, were determined spectrophotometrically in CCl4 solutions The order of stability for the halogen series was ICI > IBr > I2, in agreement with the acidic strength of the halogens. The order of stability for the amine series was 2-picoline > pyridine > 2,6-lutidine. The low stability of 2,6-lutidine complexes is ascribed to steric effects. The absorption spectra of acetonitrile solutions of the 6 addition compounds had maximum at either the 227 mμ peak of ICl2, or the 256 mμ peak of IBr2, indicating an ionic dissociation in this polar solvent, as opposed to mol. dissociation in nonpolar CCl4.

Journal of the American Chemical Society published new progress about 6443-90-9. 6443-90-9 belongs to iodides-buliding-blocks, auxiliary class Pyridines, name is Pyridine Iodochloride complex, and the molecular formula is C5H5ClIN, Recommanded Product: Pyridine Iodochloride complex.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Landauer, S. R.’s team published research in Journal of the Chemical Society in | CAS: 31253-08-4

Journal of the Chemical Society published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Recommanded Product: Ethyl 2-Iodopropionate.

Landauer, S. R. published the artcileThe organic chemistry of phosphorus. I. Some new methods for the preparation of alkyl halides, Recommanded Product: Ethyl 2-Iodopropionate, the publication is Journal of the Chemical Society (1953), 2224-34, database is CAplus.

cf. C.A. 45, 9456e. (MeO)3P (I) (0.1 mol) refluxed 30 min. at 100° with MeI and the product distilled, gave MePO(OMe)2 (II); with molar ratios of I:MeI = 1:1, 2:1, 10:1, and 100:1, the yields of II were 90, 88, 93, and 80%, resp. I (6.2 g.) and 0.06 g. Me2SO4 refluxed 15 min. at 100° gave 8% recovered I and 81% II, b12 66°. (PhO)3P (III) (31 g.) and 21 g. MeI refluxed 36 h. with exclusion of H2O, the mixture treated with anhydrous ether, and the solid washed with anhydrous ether, dried, and weighed in vacuo, gave 42 g. (PhO)3PMeI (IV), which was stored under ether, dried, and weighed in vacuo before use; IV taken up in Me2CO and precipitated with anhydrous ether gave pure IV, m. 146°. IV (7.95 g.) in 30 mL. absolute EtOH and 150 mL. saturated alc. AgNO3 gave after 3, 6, 10, 20, 80, 150, and 1440 min. 67, 73, 76, 79, 86, 92, and 100%, resp., total yield of AgI (204.5 mg. IV gave 09.6% AgI after 3 min.). IV (21 g.) shaken several min. with 35 mL. absolute EtOH and the solution distilled, gave 62% EtI, b. 72° (PhNEtMe2I, m. 136-7°), PhOH, and 91% MePO(OPh)2 (V), m. 35-6°. In a 2nd experiment in which the mixture was distilled at 0.5 mm., 66% EtI was collected in a trap at -80°; the residue, washed with 2N NaOH gave 86% V; the alk. washings gave with acid 96% PhOH. Iodides were similarly prepared from IV and the appropriate alc., cooling being necessary with reactive alcs., warming with less reactive alcs.; the iodide was isolated by distillation of the reaction mixture in vacuo, with the iodide collected at -80° in a trap (when the b.p. was much lower that of PhOH), by distillation with PhOH in vacuo and separation of the PhOH with cold dilute NaOH, or by removal of the PhOH from the reaction mixture with dilute NaOH and distillation The method is satisfactory with primary, secondary, tertiary (76% yield of Me3CI), and unsaturated alcs. (83% yield of MeCH:CHCH2I, b40-5 55-6°), glycols (95% yield of CH2(CH2I)2, b0.5 50-1°, n21D 1.6420), and Et lactate (92% yield of MeCHICO2Et, b8 65-6°, n20.5D 1.5000), giving 60-95% yields. Cholesterol (9.5 g.) mixed with 12 g. IV, 10 mL. MeI added, the mixture refluxed 1 h. at 50-60°, kept overnight, extracted with 100 mL. petr. ether (b. 40-60°), the extract evaporated, the residue treated with 100 mL. H2O, the insoluble part washed with Me2CO, taken up in 200 mL. hot Me2CO, cooled, and the solution decanted from the oil and cooled at 2° gave 30% cholesteryl iodide, m. 105° (from EtOAc), [α]21.2D -12.7° (CHCl3). III (34 g.) and 13 g. PhCH2Cl heated 60 h. at 170-5° and the mixture washed with petr. ether (b. 40-60°), gave 25 g. oily (PhO)3P(CH2ph)Cl (VI). VI (10 g.) kept overnight at room temperature with 2 g. (+)-2-octanol, α21.4D 7.72°, and the mixture distilled gave 79% (-)-2-chloroöctane, b13 60°, n20D 1.4275, [α]22.4D -24.72°. PCl3 (23 g.) added (20 min.) to 54 g. stirred, cooled PhCH2OH, 61 g. PhNMe2, and 100 mL. absolute ether, the mixture filtered, and the filtrate distilled twice gave 8 g. (PhCH2O)2P(O)H, b0.05 145-60°, 10 g. mixture, b0.05 160-80°, and 18 g. (PhCH2O)3P (VII), b0.05 180-95°, m. 52° (from petr. ether). VII and MeI heated 30 h. at 100° gave no addition product; heated 3 h. at 150°, VII and MeI gave PhCH2I. Summaries are given for the preparation of 12 iodides, 4 bromides, and 5 chlorides directly from III, the halide (MeI, PhCH2Br, or PhCH2Cl), and the alc. III (68 g.), 40 g. BuI, and 6.4 g. absolute MeOH heated 24 h. at 165-85°, with the MeI fractionated off continuously, gave 16 g. MeI, b. 42-3°, n20D 1.5290. MeBr passed slowly (through a sintered glass plate) into a mixture of 50 g. III and 11 g. BuOH heated 12 h. (155-35°), the mixture distilled, and the product collected at -80°, gave 63% BuBr, b. 101.5°, n20D 1.4400. (EtO)3P (16.6 g.), 14.2 g. MeI, and 22.2 g. BuOH refluxed 1 h. gave 64% impure EtI and 36% BuI, b. 110-30°, n20D 1.4935. Dry HCl passed (1.5 h.) into equimol. amounts of III and BuOH gave 76% BuCl, b. 77-9°, n17D 1.4025; similarly (-)-2-octanol (kept overnight with III before HCl was added for 1 h.) gave 44% (+)-2-chloroöctane, b8-10 53-6°, [α]22.2D 18.8°; 2 g. cholesterol, 5 g. III, and HCl (30 min. addition), treated with 20 mL. Me2CO, gave 2.2 g. cholesteryl chloride, m. 95° (from EtOAc), [α]20D -33.3° (CHCl3). III (34 g.), 7.4 g. BuOH, and 6 g. NH4Cl refluxed 84 h. at 140° gave 63% BuCl, b. 77-8°, n22D 1.4015. Similarly III and BuOH with 6 g. NaCl (heated 120 h. at 170-80°) gave 16% BuCl; with 9.6 g. LiBr (heated 64 h. at 140°), 40% BuBr; with 16.5 g. NaI (heated 64 h. at 160-70°), 18.5% BuI. IV (7 g.), 1.5 g. absolute EtOH, and 3 g. PhNMe2 warmed 15 min. on a steam bath and diluted with ether gave 3.8 g. PhNMe2EtI, m. 131° (from EtOH). III (68 g.) and 14.8 g. BuOH heated 16 h. at 100° gave 18.5 g., b10 60-80° (mainly PhOH), 7.5 g., b10 80-120°, n25D 1.4580 [mainly (BuO)3P], 7.8 g. mixture, b10 120-40°, n25D -1.4840, of (BuO)3P and (BuO)2P(O)Ph, 9 g., b10 140-70°, n25D 1.5302, [mainly BuOP(OPh)2 (VIII)], 4.1 g., b10 170-80°, n25D 1.5819, (mixture of VIII and III), and 28 g. residue, n25D 1.5815. III (68 g.) and 14.8 g. BuOH kept 30 min. at room temperature and distilled gave 18 g. PhOH and a mixture of phosphites which, refluxed 3 h. with 13 g. MeI, gave 13 g. BuI, n23D 1.4990; the residue heated 24 h. with 28 g. MeI gave 15.1 g. addnl. BuI, b. 125-31°, n22D 1.4980. IV (23 g.) and 3 g. V refluxed 1 h. and distilled gave 5 g. MeI, b. 42-4°, n20D 1.5055. IV (5 g.) and 2.5 g. (BuO)3P mixed to give a solution and distilled gave 1.8 g. BuI, b. 125-32°, n23D 1.4970. Et(O)PCl2 (IX) (147 g., b. 117-18°) and 500 mL. absolute ether cooled in a freezing mixture and treated portion wise with NaOMe (from 46 g. powd. Na and 64 g. MeOH) in 500 mL. ether, the mixture kept 1 h. at room temperature, filtered, the filtrate distilled, and the product fractionated gave 56 g. EtOP(OMe)2 (X), b. 124-7°, equivalent 138.0 (equivalents were determined by hydrolysis of about 150 mg. alkyl phosphite 1 h. at 100° with 5 mL. 70% alc. NaOH, dilution with 0.1N HCl, and titration of the excess alkali with bromophenol blue; the authors found that equivalents gave a better criterion of purity than elemental anal.). X (27.6 g.) refluxed 1 h. with 28.4 g. MeI and fractionated gave 27.5 g. MeI and 27 g. EtO(MeO)P(O)Me, b15 74-5°, equivalent 137.8. X (13.8 g.), 2 g. H2O, and 10 mL. Me2CO kept 1 h. and distilled gave P-containing fractions, 1.3 g., b15-17 65-73°, 9 g. EtO(MeO)(HO)P, b15-17 73-5°, equivalent 124.0, and 1.3 g., b15-17 75-7°. Absolute MeOH (32 g.) and 121 g. PhNMe2 added (1 h.) to 137 g. PCl3 cooled, stirred in 1 l. absolute ether, 92 g. absolute EtOH, and 242 g. PhNMe2 then added (2 h.), the mixture diluted with 500 mL. ether, filtered, the filtrate distilled, and the fraction, b10-15 50-90°, fractionated gave 35 g. (EtO)2POMe (XI), b. 136-9°, equivalent 152.6. XI (10 g.) and 8.5 g. MeI refluxed 30 min. and distilled gave 6.8 g. MeI and 6 g. (EtO)2P(O)Me, b. 190-2°, n23D 1.4110, equivalent 152.0. XI (10 g.), 1.5 g. H2O, and 10 mL. Me2CO gave 5.3 g. (EtO)2POH, b8 65-6°, n21D 1.4070, equivalent 137.2. iso-PrOH (120 g.) and 242 g. PhNMe2 added (80 min.) to cold 130 g. IX in 500 mL. absolute ether, the mixture stirred 30 min. and filtered, and the filtrate fractionated gave 97 g. (iso-PrO)2POEt (XII), b10 69-71°, equivalent 192.1. XII (19.5 g.) and 14.2 g. MeI refluxed 30 min. at 100° and distilled gave 12 g. EtI, b. 71-3°, and 17 g. (iso-PrO)2P(O)Me, b5 7-5-6°, n20D 1.4158. XII (19.5 g.), 2 g. H2O, and 10 mL. Me2CO refluxed 14 h. and distilled gave 12.5 g. (iso-PrO)2P.OH, b10 89-90°, equivalent 159.3. The mechanism for the formation of alkyl halides is discussed. Halides included in tables: EtI, iso-PrI, n-BuI, sec-BuI, tert-BuI, (+)- and (-)-2-iodoöctane, cyclohexyl iodide, CH2:CHCH2I, MeCH:CHCH2Cl, PhCH2I, PhCH2CH2I, PhCHIMe, CH2(CH2I)2, MeCHICO2Et, Me2C(CH2I)2, and Me3CCH2I; BuBr, CH2:CHCH2Br, CH2(CH22Br)2, MeCHBrCO2Et; BuCl, CH2:CHCH2Cl, CH2(CH2Cl)2, MeCHClCO2Et, and n-C6H13Cl.

Journal of the Chemical Society published new progress about 31253-08-4. 31253-08-4 belongs to iodides-buliding-blocks, auxiliary class Iodide,Ester, name is Ethyl 2-Iodopropionate, and the molecular formula is C5H9IO2, Recommanded Product: Ethyl 2-Iodopropionate.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com

Druzhinin, S. I.’s team published research in Proceedings – Indian Academy of Sciences, Chemical Sciences in 107 | CAS: 606-55-3

Proceedings – Indian Academy of Sciences, Chemical Sciences published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Related Products of iodides-buliding-blocks.

Druzhinin, S. I. published the artcileExcited state relaxation processes of crowned styryl dyes and their metal complexes, Related Products of iodides-buliding-blocks, the publication is Proceedings – Indian Academy of Sciences, Chemical Sciences (1995), 107(6), 721-7, database is CAplus.

The fluorescence of novel crown ether styryl dyes and their complexes with sodium cation was studied. The fluorescence quantum yield of crown ether styryl dyes is higher than that of dyes not containing crown ethers. While absorption and fluorescence spectra of a styryl dye are shifted to high frequency regions, its fluorescence quantum yield in the absence of photoisomerization is practically unchanged, and the rate constant of its fluorescence quenching rises as it forms a complex with the metal ion. The relaxation processes of photoisomerization and recoordination are considered. The adiabatic change of metal ion coordination in the crown ether may proceed in the excited state. The trans-cis photoisomerization of styryl dyes and their metal complexes is a barrierless reaction.

Proceedings – Indian Academy of Sciences, Chemical Sciences published new progress about 606-55-3. 606-55-3 belongs to iodides-buliding-blocks, auxiliary class Quinoline,Salt, name is 1-Ethyl-2-methylquinolin-1-ium iodide, and the molecular formula is C12H14IN, Related Products of iodides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Iodide,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com