Synthesis of 1,2,4-Triazoles, N-Fused 1,2,4-Triazoles and 1,2,4-Oxadiazoles via Molybdenum Hexacarbonyl-Mediated Carbonylation of Aryl Iodides was written by Nakka, Mangarao;Tadikonda, Ramu;Nakka, Srinivas;Vidavalur, Siddaiah. And the article was included in Advanced Synthesis & Catalysis in 2016.Reference of 5460-32-2 This article mentions the following:
A convenient and efficient protocol was developed for the synthesis of 1,2,4-triazoles, N-fused 1,2,4-triazoles and 1,2,4-oxadiazoles from aryl iodides and amidrazones, 2-hydrazinylpyridine, 2-hydrazinylpyrazine or amidoximes using molybdenum hexacarbonyl which acts as a convenient and reliable solid source of carbon monoxide. This procedure provided an easy access to a library of 1,2,4-triazole, N-fused 1,2,4-triazole and 1,2,4-oxadiazole derivatives in fair to good yields without the need of gaseous carbon monoxide and palladium catalysts. In the experiment, the researchers used many compounds, for example, 4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2Reference of 5460-32-2).
4-Iodo-1,2-dimethoxybenzene (cas: 5460-32-2) belongs to iodide derivatives. Generally organic iodides can be divided into two classes of alkyl iodides and aryl iodides. Typical reactions of alkyl iodides include nucleophilic substitution, elimination, reduction, and the formation of organometallics. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Reference of 5460-32-2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com