Highly Enantioselective Cross-Electrophile Aryl-Alkenylation of Unactivated Alkenes was written by Tian, Zhi-Xiong;Qiao, Jin-Bao;Xu, Guang-Li;Pang, Xiaobo;Qi, Liangliang;Ma, Wei-Yuan;Zhao, Zhen-Zhen;Duan, Jicheng;Du, Yun-Fei;Su, Peifeng;Liu, Xue-Yuan;Shu, Xing-Zhong. And the article was included in Journal of the American Chemical Society in 2019.Related Products of 877264-43-2 This article mentions the following:
Enantioselective cross-electrophile reactions remain a challenging subject in metal catalysis, and with respect to data, studies have mainly focused on stereoconvergent reactions of racemic alkyl electrophiles. Here, the authors report an enantioselective cross-electrophile aryl-alkenylation reaction of unactivated alkenes. This method provides access to a number of biol. important chiral mols. such as dihydrobenzofurans, indolines, and indanes. The incorporated alkenyl group is suitable for further reactions that can increases mol. diversity and complexity. The reaction proceeds under mild conditions at room temperature, and an easily accessible chiral pyrox ligand was used to afford products with high enantioselectivity. The synthetic utility of this method is demonstrated by enabling the modification of complex mols. such as peptides, indometacin, and steroids. In the experiment, the researchers used many compounds, for example, (5-Fluoro-2-iodophenyl)methanol (cas: 877264-43-2Related Products of 877264-43-2).
(5-Fluoro-2-iodophenyl)methanol (cas: 877264-43-2) belongs to iodide derivatives. Organic iodides are organic compounds containing a carbon-iodine (C-I) bond. The carbon-iodine bond is weaker than other carbon-halogen bonds due to the poor electronegative nature of the iodine atom. Iodo alkanes participate in a variety of organic synthesis reactions, which include the Simmons–Smith reaction (cyclopropanation using iodomethane), Williamson ether synthesis, Wittig reaction, Grignard reaction, alkyl coupling reactions, and Wurtz reaction.Related Products of 877264-43-2
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com