170112-66-0, name is 3,4,5-Trifluoroiodobenzene, belongs to iodides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. COA of Formula: C6H2F3I
1 mmol of cp-2-19 was dissolved in 10 ml of anhydrous acetonitrile and 0.05 mmol of Pd (OAc) 2,0.1 mmol of P (O-Tolyl) 3 and 3 mmol of Et3N, followed by addition of 1.5 mmol of 3,4,5-trifluoroiodobenzene and Ar gas for 12 h.After filtration, the filtrate was evaporated to dryness and the dichloromethane was dissolved, washed with water, washed with saturated NaCl and treated with anhydrous MgSO4. The silica gel column (PE: EA 50: 1)To the compound
The synthetic route of 170112-66-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Peking University; Fu, Hongzheng; Chen, Peng; (29 pag.)CN106543032; (2017); A;,
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com