Karmakar, Swastik; Das, Prasanta; Kundu, Sandip published their research in New Journal of Chemistry in 2021. The article was titled 《Silver-catalyzed tandem 5- and 6-endo-cyclizations via concomitant yne-ol-imine activation: selective entry to 2-aryldihydrofuroquinolines》.Electric Literature of C6H5ClIN The article contains the following contents:
A silver(I) catalyzed domino imination-intramol. biheterocyclization-aromatization cascade has been developed to construct 2-aryl/-heteroaryl dihydrofuroquinolines in moderate to good yield using an aldehydes and unprotected 4-(2-aminophenyl)but-3-yn-1-ols as precursors. Sequential Ag-(I)-induced 5-endo-dig cyclization of the yne-ol part and 6-endo-trig cyclization of a proposed Ag-bound imine, followed by aromatization, furnish the furoquinoline derivatives In the part of experimental materials, we found many familiar compounds, such as 4-Chloro-2-iodoaniline(cas: 63069-48-7Electric Literature of C6H5ClIN)
4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Many important products require amines as part of their syntheses. Methylamine is utilized in the production of the analgesic meperidine (trade name Demerol) and the photographic developer Metol (trademark), and dimethylamine is used in the synthesis of the antihistamine diphenhydramine (trade name Benadryl), the solvent dimethylformamide (DMF), and the rocket propellant 1,1-dimethylhydrazine. The synthesis of the insect repellent N,N-diethyl-m-toluamide (DEET) incorporates diethylamine while that of the synthetic fibre Kevlar requires aromatic amines.Electric Literature of C6H5ClIN
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com