《Lewis Acid Catalyzed Atom-Economic Synthesis of C2-Substituted Indoles from o-Amido Alkynols》 was written by Garkhedkar, Amol Milind; Gore, Babasaheb Sopan; Hu, Wan-Ping; Wang, Jeh-Jeng. Recommanded Product: 4-Chloro-2-iodoaniline And the article was included in Organic Letters in 2020. The article conveys some information:
Herein a Zn(OTf)2 catalyzed synthesis of C2-alkyl substituted indole derivatives I (R = H, 6-Me, 5-F, etc.; R1 = H, 3-OMe, 4-Cl, etc.; n = 1, 2, 3) via unprecedented carbonyl group migration from o-amido alkynols is reported. The key features of this protocol involve N,O-carbonyl group migration, broad substrate scope with varied functionality tolerance, moderate to good yields, and 100% atom economy. The crossover experiments proved that the migration is happening via an intramol. pathway. In the experiment, the researchers used 4-Chloro-2-iodoaniline(cas: 63069-48-7Recommanded Product: 4-Chloro-2-iodoaniline)
4-Chloro-2-iodoaniline(cas: 63069-48-7) belongs to anime. Examples of direct uses of amines and their salts are as corrosion inhibitors in boilers and in lubricating oils (morpholine), as antioxidants for rubber and roofing asphalt (diarylamines), as stabilizers for cellulose nitrate explosives (diphenylamine), as protectants against damage from gamma radiation (diarylamines), as developers in photography (aromatic diamines), as flotation agents in mining, as anticling and waterproofing agents for textiles, as fabric softeners, in paper coating, and for solubilizing herbicides.Recommanded Product: 4-Chloro-2-iodoaniline
Referemce:
Iodide – Wikipedia,
Iodide – an overview | ScienceDirect Topics – ScienceDirect.com